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1001por Dardente, Hugues, Mendoza, Jorge, Fustin, Jean-Michel, Challet, Etienne, Hazlerigg, David G.“…Our data show that Fbxl3 function is conserved and further reveal that its closest homologue, the F-Box protein Fbxl21, also binds to CRY1 which impairs its repressive action towards the transcriptional activators CLOCK/BMAL1. …”
Publicado 2008
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1002por Mollnes, Tom Eirik“…High mobility group box (HMGB)1, originally described as a nuclear protein that binds to and modifies DNA, is now regarded as a central mediator of inflammation by acting as a cytokine. …”
Publicado 2008
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1003
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1004por Cruz-Guilloty, Fernando, Pipkin, Matthew E., Djuretic, Ivana M., Levanon, Ditsa, Lotem, Joseph, Lichtenheld, Mathias G., Groner, Yoram, Rao, Anjana“…Our data point to the existence of an elaborate transcriptional network in which Runx3 initially induces and then cooperates with T-box transcription factors to regulate gene transcription in differentiating CTLs.…”
Publicado 2009
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1005por Scott, Michelle S., Avolio, Fabio, Ono, Motoharu, Lamond, Angus I., Barton, Geoffrey J.“…Here, we investigate a possible evolutionary relationship between miRNAs and box H/ACA snoRNAs. A comparison of the genomic locations of reported miRNAs and snoRNAs reveals an overlap of specific members of these classes. …”
Publicado 2009
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1006Cardiovascular development: towards biomedical applicability: T-box factors determine cardiac design“…Insight into the roles of T-box factors in these processes will enhance our understanding of heart formation and the underlying molecular regulatory pathways.…”
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1007por Broholm, Suvi K., Pöllänen, Eija, Ruokolainen, Satu, Tähtiharju, Sari, Kotilainen, Mika, Albert, Victor A., Elomaa, Paula, Teeri, Teemu H.“…Functional studies were performed for three gerbera (Gerbera hybrida) B class MADS-box genes—PI/GLO-like GGLO1, euAP3 class GDEF2, and TM6-like GDEF1—and data are shown for a second euAP3-like gene, GDEF3. …”
Publicado 2010
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1008por Abraham, Edward“…High mobility group box protein 1 (HMGB1) has been shown to participate in acute inflammatory reactions, including acute lung injury and sepsis. …”
Publicado 2009
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1009“…BACKGROUND: Quality improvement collaboratives are often labeled as black boxes because effect studies usually do not describe exactly how the results were obtained. …”
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1010
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1011por Martins, Jessica, Oliveira, Magda, Tapiço, Maria, Nascimento, Tânia, Grenha, Ana, Braz, Luis“…Therefore, tools such as multidose pill boxes have been designed to provide the means for higher therapeutic compliance. …”
Publicado 2010
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1012por Wang, Yugang, Kheir, Michael M., Chai, Yushuang, Hu, Jun, Xing, Dongming, Lei, Fan, Du, Lijun“…Based on results from this study, we hypothesize that berberine can suppress the transcription of DNA in living cell systems, especially suppressing the association between TBP and the TATA box by binding with DNA and, thus, inhibiting TATA box-dependent gene expression in a non-specific way. …”
Publicado 2011
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1013por da Silva, Marcos Vinícius Gualberto Barbosa, Van Tassell, Curtis P., Sonstegard, Tad S., Cobuci, Jaime Araujo, Gasbarre, Louis C.“…Original data were transformed using an extension of the Box–Cox transformation to approach normality and to estimate (co)variance components. …”
Publicado 2012
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1014“…The DEAD-box helicase DDX3 has suggested functions in innate immunity, mRNA translocation and translation, and it participates in the propagation of assorted viruses. …”
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1015“…Proteins that activate decapping, such as the DEAD-box RNA helicase Dhh1, have been postulated to function by limiting translation initiation, thereby promoting a ribosome-free mRNA that is targeted for decapping. …”
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1016“…High mobility group box 1 (HMGB1) is a molecular alarm signal that triggers an immune response when released. …”
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1017por van Empel, Pieter J., van Rijssen, Lennart B., Commandeur, Joris P., Verdam, Mathilde G. E., Huirne, Judith A., Scheele, Fedde, Jaap Bonjer, H., Jeroen Meijerink, W.“…The aim of this study was to establish the internal validity of the TrEndo, a motion-tracking device, for implementation on a laparoscopic box trainer. METHODS: Face validity and content validity were addressed through a structured questionnaire. …”
Publicado 2012
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1018por Cauchi, Ruben J“…BACKGROUND: DEAD-box RNA helicase Gemin3 is an essential protein since its deficiency is lethal in both vertebrates and invertebrates. …”
Publicado 2012
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1019“…Here we show that two SCF ubiquitin ligases, SCF(Cdc4) and SCF(Grr1), redundantly target Cln3 for degradation. While the F-box proteins (FBPs) Cdc4 and Grr1 were previously thought to target non-overlapping sets of substrates, we find that Cdc4 and Grr1 each bind to all 3 G1 cyclins in cell extracts, yet only Cln3 is redundantly targeted in vivo, due in part to its nuclear localization. …”
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