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1421por Laissue, Paul“…These changes are key determinants regarding tumour’s behaviour as they contribute to cell differentiation/proliferation, migration and metastasis, as well as resistance to chemotherapeutic agents. The forkhead box (FOX) transcription factor family consists of an evolutionarily conserved group of transcriptional regulators engaged in numerous functions during development and adult life. …”
Publicado 2019
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1422“…Recently, several new embryo-like human pluripotent stem cell (hPSC)–based platforms have emerged, which are beginning to illuminate the current black box state of early human post-implantation biology. …”
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1423por Türeli, Sina“…We show that an analogue of the ball-box theorem holds true for a class of corank 1, non-differentiable tangent subbundles that satisfy a geometric condition. …”
Publicado 2018
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1424“…BACKGROUND: The morphological diversity of flower organs is closely related to functional divergence within the MADS-box gene family. Bryophytes and seedless vascular plants have MADS-box genes but do not have ABCDE or AGAMOUS-LIKE6 (AGL6) genes. …”
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1425por Cheng, Xiankun, Zhao, Yanxiang, Jiang, Qingshan, Yang, Jun, Zhao, Wensheng, Taylor, Ian A, Peng, You-Liang, Wang, Dongli, Liu, Junfeng“…In rice, the critical regulator of the salicylic acid signalling pathway is OsWRKY45, a transcription factor (TF) of the WRKY TF family that functions by binding to the W-box of gene promoters, but the structural basis of OsWRKY45/W-box DNA recognition is unknown. …”
Publicado 2019
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1426“…A review of reviews following a scoping review study design was conducted in order to deconstruct the black box of interactions between the built environment and human behaviors pertaining to physical activity and/or diet. …”
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1427por Ribalta, Carla, Koivisto, Antti J., Salmatonidis, Apostolos, López-Lilao, Ana, Monfort, Eliseo, Viana, Mar“…An industrial scenario characterized by high emissions of unintentionally-generated nanoparticles (NP) was selected to assess the performance of a one-box model. Worker exposure to NPs due to thermal spraying was monitored, and two methods were used to calculate emission rates: the convolution theorem, and the cyclic steady state equation. …”
Publicado 2019
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1428por Ahmadi, Azam, Aghabozorgi, Reza, Anoushirvani, Ali Arash, Bayatiani, Mohamadreza, Arjomandzadegan, Mohammad, Eslah, Saeedeh, Sobhani, Yasaman“…This study examines alterations of pre-messenger ribonucleic acid (pre-mRNA) splicing in X-box binding protein (XBP) transcripts related to the ER stress pathway in CRC. …”
Publicado 2019
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1429“…DEAD-box helicases (DDXs) regulate RNA processing and metabolism by unwinding short double-stranded (ds) RNAs. …”
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1430por Wang, Xinying, Miyazaki, Yukiko, Inaoka, Daniel Ken, Hartuti, Endah Dwi, Watanabe, Yoh-Ichi, Shiba, Tomoo, Harada, Shigeharu, Saimoto, Hiroyuki, Burrows, Jeremy Nicholas, Benito, Francisco Javier Gamo, Nozaki, Tomoyoshi, Kita, Kiyoshi“…In this study, we used active recombinant protein rPfMQO overexpressed in bacterial membrane fractions to screen a total of 400 compounds from the Pathogen Box, released by Medicines for Malaria Venture. …”
Publicado 2019
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1431por Kongsema, Mesayamas, Wongkhieo, Sudtirak, Khongkow, Mattaka, Lam, Eric W.-F., Boonnoy, Phansiri, Vongsangnak, Wanwipa, Wong-Ekkabut, Jirasak“…However, >90% of patients with metastatic cancer are resistant to chemotherapy. The Forkhead box M1 (FOXM1) transcription factor plays a pivotal role in the resistance of breast cancer cells to chemotherapy by promoting DNA damage repair following genotoxic drug treatment. …”
Publicado 2019
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1432por Yoshitane, Hikari, Asano, Yoshimasa, Sagami, Aya, Sakai, Seinosuke, Suzuki, Yutaka, Okamura, Hitoshi, Iwasaki, Wataru, Ozaki, Haruka, Fukada, Yoshitaka“…In mammals, Albumin D-site-Binding Protein (DBP) rhythmically activates transcription of various genes through a DNA cis-element, D-box. The DBP-dependent transactivation is repressed by competitive binding of E4BP4 to the D-box. …”
Publicado 2019
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1433por Lari, Azra, Arul Nambi Rajan, Arvind, Sandhu, Rima, Reiter, Taylor, Montpetit, Rachel, Young, Barry P, Loewen, Chris JR, Montpetit, Ben“…Dbp5 is an essential DEAD-box protein that mediates nuclear mRNP export. Dbp5 also shuttles between nuclear and cytoplasmic compartments with reported roles in transcription, ribosomal subunit export, and translation; however, the mechanism(s) by which nucleocytoplasmic transport occurs and how Dbp5 specifically contributes to each of these processes remains unclear. …”
Publicado 2019
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1434por Wang, Ying, Zhan, Di-Feng, Li, Hui-Liang, Guo, Dong, Zhu, Jia-Hong, Peng, Shi-Qing“…MADS-box transcription factors possess many functions in plant reproduction and development. …”
Publicado 2019
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1435por Hu, Jiali, Li, Ke, Li, Zhanghuan, Gao, Chao, Guo, Fei, Wang, Yingmei, Xue, Fengxia“…Sex-determining region Y box-containing genes are transcription factors with roles in multiple biological processes, including cell differentiation, proliferation, and apoptosis. …”
Publicado 2019
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1436Oncogenic splicing abnormalities induced by DEAD ‐Box Helicase 56 amplification in colorectal cancerpor Kouyama, Yuta, Masuda, Takaaki, Fujii, Atsushi, Ogawa, Yushi, Sato, Kuniaki, Tobo, Taro, Wakiyama, Hiroaki, Yoshikawa, Yukihiro, Noda, Miwa, Tsuruda, Yusuke, Kuroda, Yousuke, Eguchi, Hidetoshi, Ishida, Fumio, Kudo, Shin‐ei, Mimori, Koshi“…Alternative splicing, regulated by DEAD‐Box Helicase (DDX) families, plays an important role in cancer. …”
Publicado 2019
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1437Multimedia Modeling of Engineered Nanoparticles with SimpleBox4nano: Model Definition and Evaluationpor Meesters, Johannes A. J., Koelmans, Albert A., Quik, Joris T. K., Hendriks, A. Jan, van de Meent, Dik“…Here, we present SimpleBox4Nano (SB4N) as the first model of this type, assess its validity, and evaluate it by comparisons with a known material flow model. …”
Publicado 2014
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1438“…Once ubiquitous, North American box turtles are experiencing reductions in abundance and range, but the magnitude of these losses is largely unknown. …”
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1439por Zhang, Shulin, Tian, Zailong, Li, Haipeng, Guo, Yutao, Zhang, Yanqi, Roberts, Jeremy A., Zhang, Xuebin, Miao, Yuchen“…BACKGROUND: F-box proteins are substrate-recognition components of the Skp1-Rbx1-Cul1-F-box protein (SCF) ubiquitin ligases. …”
Publicado 2019
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1440por Tang, Wen, Tu, Yayi, Cheng, Xiaojie, Zhang, Lili, Meng, Hengling, Zhao, Xin, Zhang, Wei, He, Bin“…The MADS-box gene family encodes transcription factors with many biological functions that extensively regulate plant growth, development and reproduction. …”
Publicado 2019
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