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1521
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1522
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1523
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1524por Mao, Xinguo, Yu, Chunmei, Li, Long, Wang, Min, Yang, Lili, Zhang, Yining, Zhang, Yanfei, Wang, Jingyi, Li, Chaonan, Reynolds, Matthew Paul, Jing, Ruilian“…Ubiquitination is a major type of post-translational modification of proteins in eukaryotes. The plant U-Box (PUB) E3 ligase is the smallest family in the E3 ligase superfamily, but plays a variety of essential roles in plant growth, development and response to diverse environmental stresses. …”
Publicado 2022
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1525“…OBJECTIVE: The aim of this study was to determine the correlation between manual dexterity evaluated with the Box and Block Test (BBT) and the performance of daily activities in children with bilateral cerebral palsy (CP). …”
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1526“…We showed that box C/D, but not box H/ACA, snoRNPs are required for the full function of UPR(mt) and ESRE upon stress. …”
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1527
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1528“…INTRODUCTION: Diabetic patients routinely have high levels of high mobility group box 1 (HMGB1) protein in their plasma, vitreous and ocular membranes, which is strongly correlated with subclinical chronic inflammation in the eye. …”
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1529por Whitman, Brendan T., Murray, Cameron R.A., Whitford, Denise S., Paul, Simanta S., Fahlman, Richard P., Glover, Mark J.N., Owttrim, George W.“…Here, we provide in vivo evidence that proteolytic degradation of the cyanobacterial DEAD-box RNA helicase CrhR is conditional, being initiated by a temperature upshift from 20 to 30 °C in the model cyanobacterium, Synechocystis sp. …”
Publicado 2022
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1530“…DEAD/H-box proteins are the largest family of RNA helicases in mammalian genomes, and they are present in all kingdoms of life. …”
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1531“…This paper proposes a learnable line encoding technique for bounding boxes commonly used in the object detection task. …”
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1532Application of QUBO solver using black-box optimization to structural design for resonance avoidance“…However, their applications are still limited due to the difficulty of transforming from the original optimization problem to QUBO. Recently, black-box optimization (BBO) methods have been proposed to tackle this issue using a machine learning technique and a Bayesian treatment for combinatorial optimization. …”
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1533“…The differential box-counting (DBC) method is useful for determining the fractal dimension of grayscale images. …”
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1534por Penty, Samuel E., Zwijnenburg, Martijn A., Orton, Georgia R. F., Stachelek, Patrycja, Pal, Robert, Xie, Yujie, Griffin, Sarah L., Barendt, Timothy A.“…By exploiting the new bay connectivity of twisted PDIs, a dynamic bis-PDI macrocycle (the “Pink Box”) is realized in which homochiral PDI–PDI π–π stacking interactions are switched on exclusively. …”
Publicado 2022
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1535
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1536por Xi, Xi, Li, Haochen, Chen, Shengquan, Lv, Tingting, Ma, Tianxing, Jiang, Rui, Zhang, Ping, Wong, Wing Hung, Zhang, Xuegong“…There could be many intermediate steps at epigenetic, transcriptomic, and cellular scales inside the black box of genotype-phenotype associations. In this article, we present a machine-learning-based cross-scale framework GRPath to decipher putative causal paths (pcPaths) from genetic variants to disease phenotypes by integrating multiple omics data. …”
Publicado 2022
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1537por Jiang, Yanhui, Yang, Lewei, Jiang, Ling, Yu, Wenyan, Jin, Zhongwen, Qiu, Yeqing, Liao, Yifeng, Liu, Jihong, Zhang, Hongyu“…Intriguingly, the genomic alteration of X-box binding protein 1 (XBP1), the important mediator of chemotherapy-induced cancer immunogenic cell death, was found to be a potential coregulator of immune checkpoints in ovarian cancer. …”
Publicado 2022
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1538
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1539por Tamilarasan, Neelakandan, Yasmin, Begum M., Anitha, Posina, Umme, Hani, Cheng, Wan Hee, Mohan, Sellapan, Ramkanth, Sundarapandian, Janakiraman, Ashok Kumar“…PAC-containing transferosomes were prepared using the film hydration method and then loaded into a 4% methylcellulose gel. A 2(3) Box–Behnken design was used to optimize the PAC-loaded transferosomal gel, where the effects of phospholipid 90 G (X1), Tween 80 (X2), and sonication time (X3) were evaluated. …”
Publicado 2022
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1540“…The changes included addition of information from large observational studies using real‐world evidence, removal of the boxed warning, and a revision of the 2‐year lifetime limitation. …”
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