“…About 10 hospitals collaborated with the Eye Bank under Human Cornea Retrieval Program (HCRP). Eye Bank recruited Eye Donation Counselors (EDCs) to approach family members of the deceased. …”
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“…Abx-induced gut dysbiosis has significant, long-term effects on the development of the cornea, and reversal of these suppressive effects takes a long time.…”
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“…SMG in 4.4% HPMC solution resulted in ΔT(m) of 6.3 ± 1.21, while other concentration showed no differences in T(m) shift on porcine cornea. In ex vivo rabbit cornea, there was a trend toward an increasing cross-linking effect with higher viscosity albeit mild differences. …”
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“…We found that the porcine cornea was composed of 6–8 epithelial cell layers, stroma, Descemet’s membrane, and an endothelial monolayer. …”
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“…As the cornea is one of the most transplanted tissues in the body it has placed a burden on the provision of corneas from cadaveric donors. …”
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“…The results of in vitro release suggested BN—NLC gel can prolong the release of baicalin comparing with BN eye drops and BN—NLC. Ex vivo cornea permeation study was evaluated using Franz diffusion cells. …”
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“…Ocular herpes simplex virus 1 (HSV-1) infection leads to an immunopathogenic disease called herpes stromal keratitis (HSK), in which CD4(+) T cell-driven inflammation contributes to irreversible damage to the cornea. Herpesvirus entry mediator (HVEM) is an immune modulator that activates stimulatory and inhibitory cosignals by interacting with its binding partners, LIGHT (TNFSF14), BTLA (B and T lymphocyte attenuator), and CD160. …”
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“…TRANSLATIONAL RELEVANCE: Integrating in vivo measurement of IOP and ocular pulse amplitude, the OPE method may lead to a new clinical tool for safe and quick biomechanical evaluations of the cornea.…”
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“…CONCLUSION: A relatively larger graft size compared to the host cornea and more donor ECD might help endothelial survival in patients with BK. …”
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“…Visible aerosol production was abolished when HPMC was used to coat the cornea. This effect lasted for an average of 67 ± 8 s in the static model. …”
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“…METHODS: The expression of PTEN on cornea was compared between normal and diabetic mice. …”
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“…PURPOSE: To determine the effect of smoking on tear stability and ocular surface of the cornea among students aged between 19 and 25 years. …”
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“…CONCLUSIONS: Topical rhHGF applied three times a day during the early postoperative period prior to epithelial closure did not significantly change the corneal epithelial healing rate, myofibroblast density, or opacity compared with vehicle after transepithelial −9.0 D PRK injury of the central cornea in rabbits. TRANSLATIONAL RELEVANCE: HGF has been reported to decrease myofibroblast generation and fibrosis in many organs, but topical HGF applied to the cornea until epithelial healing had no effect on scarring fibrosis in rabbit corneas.…”
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“…PURPOSE: Contact lenses, osmotic stressors, and chemical burns may trigger severe discomfort and vision loss by damaging the cornea, but the signaling mechanisms used by corneal epithelial cells (CECs) to sense extrinsic stressors are not well understood. …”
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“…Organ culture of treated corneas showed a normal corneal epithelium following FS machining while BAK-treated corneas showed extensive epithelial and stromal damage at 24 hours posttreatment. …”
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“…METHODS: Twenty-one postvitrectomy eyes of 21 patients with cataract between April 2017 and December 2019 were enrolled. PPCCC through the cornea incision was performed before in-the-bag intraocular lens implantation. …”
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“…The central cornea was scanned by optical coherence tomography (OCT). …”
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“…METHODS: MaFIA mice were infected with 500 plaque-forming units of HSV-1 in the cornea following scarification. From day 10 to day 13 post-infection (pi), mice were treated with 40 µg/day of AP20187 (macrophage ablation) or vehicle intraperitoneally. …”
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“…RATIONALE: Patients with bullous keratopathy (BK) treated by Descemet stripping automated endothelial keratoplasty (DSAEK) have a compromised cornea, due to the administration of topical steroid, postsurgical use of contact lenses, and impaired barrier function of the corneal epithelium by BK. …”
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“…PURPOSE: To assess the axial, radial and tangential limbus position misrepresentation when parametric models are used to represent the cornea and the sclera. METHODS: This retrospective study included 135 subjects aged 22 to 65 years (36.5 mean ±9.8 STD), 71 females and 64 males. …”
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