“…Immunohistochemistry on corneal endothelium using antibodies to intercellular adhesion molecule (ICAM-1), phalloidin, CD68 (anti-macrophage), MCA967 (anti-granulocyte), T cell receptor alpha/beta (TCR alpha/beta; anti-lymphocyte), zonula occludens-1 (ZO-1), and occludin was performed on flat-mount corneas and was analyzed using a three dimensional (3D) laser confocal microscope. …”
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“…Collagen type II was not detected in Y-27632 or vehicle-only corneas. With Y-27632 treatment, α-SMA expression increased and the collagen type III signal became in the weaker subepithelial area. …”
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“…Clinical sequelae of MGK appeared abruptly three weeks after exposure, and included profound anterior edema, recurring corneal erosions, basement membrane disorganization, basal cell necrosis and stromal degeneration. Unlike resolved corneas, MGK corneas exhibited frustrated corneal wound repair, with significantly elevated histopathology scores. …”
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“…CONCLUSIONS/SIGNIFICANCE: Hevin is transiently expressed in the IrrPTK-injured corneas and loss of hevin predisposes them to aberrant wound healing. …”
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“…All available tissues (corneas, heart valves, skin and bone marrow) from donors with IgG reactivity were tested for presence of Coxiella DNA by PCR. …”
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“…Compared with AK, TCRPs were more accurate in predicting postoperative residual astigmatism in highly irregular corneas.…”
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“…Digital photographs of the corneas were acquired and the area of NV was calculated. …”
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“…This study revealed that the enzymatic resistance was greater in CXL corneas than non-irradiated corneas (p < 0.0001). …”
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“…PURPOSE: To evaluate the effect of media composition and storage method on pre-prepared Descemet's membrane endothelial keratoplasty (DMEK) grafts. METHODS: 50 corneas were used. Endothelial wound healing and proliferation in different media were assessed using a standard injury model. …”
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“…Minor differences separate this new species from Pylopaguropsis teevana in the relative length of the antennal acicles (exceeding the corneas versus not exceeding the corneas in Pylopaguropsis teevana); dorsal armature of the right chela (smooth or with scattered minute tubercles versus with numerous small tubercles in Pylopaguropsis teevana); surface shape of the lateral face of the dactyl of right pereopod 3 (evenly convex versus flattened in Pylopaguropsis teevana); and coloration (red bright red stripes versus brown stripes in Pylopaguropsis teevana). …”
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“…The overall ECD loss was 56% (95% CI: 50–62%); the ECD loss was 51.3% and 61.2% in corneas from donors younger and older than 60 years respectively (p = 0.056); likewise, the ECD loss was 52.6% and 61.0% in corneas with PT shorter and longer than 10 days respectively (p = 0.289). …”
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“…These results suggest that the TopconTRK-2P is a reliable device for evaluating CCT in healthy corneas compared with Lenstar 900.…”
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“…DI treatment decreased the cytokine levels in infected corneas and in HCECs stimulated with A. fumigatus. …”
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“…PURPOSE: This study aimed to evaluate and compare the discriminating ability of corneal elevation maps generated using a swept-source optical coherence tomography (SS-OCT) (SS-OCT ANTERION, Heidelberg Engineering, Heidelberg, Germany), which was estimated with different reference surfaces, to distinguish normal corneas from those with keratoconus and keratoconus suspect. …”
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“…Here, we present a protocol for isolating BCAM-positive cells from human donor corneas by flow cytometry and cell sorting. We describe steps for cell dissection and dissociation, antibody staining, and flow cytometry. …”
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“…We will review the current knowledge on patient selection for CXL, its indications, and options in special cases (such as thin corneas).…”
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“…Since its first description by Ernst Fuchs in 1910, the only therapeutic choice has been corneal transplantation using donor corneas. However, accumulating evidence suggests that a change in this “rule” may be imminent. …”
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“…Furthermore, the NOX2 expression levels in the corneas of the diabetic rats treated with APX-115A were restored to the levels observed in normal rats. …”
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“…Sequences of PCR products from all four cases showed 100% identity with strains of Vittaforma corneae previously reported from an outbreak in Singapore. …”
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“…The study design and methodology complied with International Standard Organization (ISO) tonometer evaluation guidelines, except the inclusion of thin (<500 µm) and thick (>600 µm) corneas. All eyes were randomised to IOP measurement by one of five standard Goldmann prisms and five modified prisms. …”
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