“…In spite of the increased corneal thickness and steep corneas, lens thickness and endothelial cell counts were normal. …”
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“…We also find a significant increase in HPSE release in vivo during infection of murine corneas and that knockdown of HPSE in vivo inhibits virus shedding. …”
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“…However, because of the late presentation, the corneas could not be salvaged. Extensive surgical reconstruction of both eyelids and bilateral penetrating keratoplasty was ultimately performed successfully to protect the ocular surfaces while trying to maximize the visual potential. …”
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“…The impact of ultrastable gold nanoparticles on wound healing dynamics is assessed on tissue engineered corneas. These results highlight the potential of ultrastable gold nanoparticles as a drug delivery system in ocular therapy.…”
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“…PBA treatment caused viral inhibition in cultured human corneas and human skin grafts as well as murine models of ocular and genital HSV infection. …”
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“…Wilson disease (WD) (OMIM# 277900) is an autosomal recessive inherited disorder characterized by excess copper (Cu) storage in different human tissues, such as the brain, liver, and the corneas of the eyes. It is a rare disorder that occurs in approximately 1 in 30,000 individuals. …”
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“…On examination he had large corneas with horizontal diameter of 14 mm, increased axial length, faint corneal stromal opacity and Haab's striae of both eyes. …”
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“…In the developing world, manual dissection is still the primary technique of lamellar keratoplasty and many precious corneas get wasted because of intra-operative unintended errors of dissection and trephination. …”
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“…Fresh frozen sections of donor corneas at various ages (18, 33, 54, and 68 years) were immunostained in situ. …”
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“…Patients with hyperthyroidism had thicker corneas compared to euthyroid individuals. Corneal thickness was also negatively associated with plasma TSH levels. …”
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“…Although they nest on land, these animals spend a large part of their lives in the ocean, which entails a series of eye adaptations such as well-developed nictitating membranes, palpebral scales, highly sensitive corneas, or sclerotic rings to protect the eye. In our study, we performed a morphometric analysis of the loggerhead turtle (Caretta caretta) eyeball and its internal structures using advanced imaging techniques such as computed tomography (CT). …”
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“…Nowadays, treating corneal diseases arising from injury to the corneal endothelium necessitates donor tissue, but these corneas are extremely scarce. As a result, researchers are dedicating significant efforts to exploring alternative approaches that do not rely on donor tissues. …”
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“…Retinal action potentials were recorded at the corneas of light-adapted wolf spider eyes in response to large positive and negative step changes in background illumination. …”
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“…The culture of human corneal endothelial cells (CECs) is critical for the development of suitable graft alternative on biodegradable material, specifically for endothelial keratoplasty, which can potentially alleviate the global shortage of transplant-grade donor corneas available. However, the propagation of slow proliferative CECs in vitro can be hindered by rapid growing stromal corneal fibroblasts (CSFs) that may be coisolated in some cases. …”
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“…The pterygia extended onto the corneas for 4.69±1.2 (range 3 to 7) mm. Only one eye (2%) demonstrated recurrent pterygium growth which responded to subconjunctival mitomycin C injection. …”
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“…However, because the patients complained of foreign body sensation, fluorescein staining of the affected eye was performed. On examination, the corneas had epithelial defects and linear scratch marks. …”
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“…The need for tissue-engineered corneas is largely a response to the shortage of donor tissue and the lack of suitable alternative biological scaffolds preventing the treatment of millions of blind people worldwide. …”
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“…To restore the ocular surface in advanced stem cell deficient corneas, an autologous or allogenic limbal stem cell transplantation is performed. …”
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“…We now demonstrate feasibility, efficacy and safety of our targeted nanocarrier for delivery of bone marrow cells (BMC) to cutaneous wound tissues and grafted corneas and its advantages over conventional BMC transplantation in mouse models for wound healing and neovascularization. …”
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“…Two other transplant recipients received corneas but remained well after receiving timely rabies prophylaxis. …”
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