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Enfermedades
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1
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1
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Cornea
1
Crítica e interpretación
1
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1221“…Simultaneous corneal cross-linking (CXL) has been proposed as an adjunct therapy to corneal refractive procedures to prevent future ectasia, especially when performed in borderline corneas. This review analyses the currently available literature (minimum follow-up 6 months) on corneal refractive surgery and simultaneous CXL (PRK Xtra, LASIK Xtra, and SMILE Xtra) to evaluate the overall results including the safety, efficacy, and potential complications associated with these procedures. …”
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1222“…METHODS: An e-mail survey was conducted among cornea surgeons and eye bankers of India. Participants were asked to report their practice patterns for the management of corneal perforation during lockdown, different preservative media used during and before lockdown, and waiting time and waiting time before COVID-19 lockdown. …”
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1223“…Under physiological conditions, the cornea is exposed to various enzymes, some of them have digestive actions, such as amylase and collagenase that may change the ultrastructure (collagen morphology) and sequentially change the mechanical response of the cornea and distort vision, such as in keratoconus. …”
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1224por Zhang, Hui, Tian, Lei, Guo, Lili, Qin, Xiao, Zhang, Di, Li, Lin, Jie, Ying, Zhang, Haixia“…OBJECTIVE: To more comprehensively evaluate the ability of the parameters reflecting the morphological and biomechanical properties of the cornea to distinguish clinical keratoconus (CKC) and forme fruste keratoconus (FFKC) from normal. …”
Publicado 2021
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1225por Chandru, Arun, Agrawal, Parinita, Ojha, Sanjay Kumar, Selvakumar, Kamalnath, Shiva, Vaishnavi K., Gharat, Tanmay, Selvam, Shivaram, Thomas, Midhun Ben, Damala, Mukesh, Prasad, Deeksha, Basu, Sayan, Bhowmick, Tuhin, Sangwan, Virender Singh, Singh, Vivek“…Herein, we report the use of human cornea derived decellularized ECM (dECM) microparticles dispersed in human fibrin sealant as an accessible therapeutic alternative for corneal anterior stromal reconstruction. dECM microparticles had good particle size distribution (≤10 µm) and retained the majority of corneal ECM components found in native tissue. …”
Publicado 2021
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1226por Collin, Joseph, Queen, Rachel, Zerti, Darin, Bojic, Sanja, Dorgau, Birthe, Moyse, Nicky, Molina, Marina Moya, Yang, Chunbo, Dey, Sunanda, Reynolds, Gary, Hussain, Rafiqul, Coxhead, Jonathan M., Lisgo, Steven, Henderson, Deborah, Joseph, Agatha, Rooney, Paul, Ghosh, Saurabh, Clarke, Lucy, Connon, Che, Haniffa, Muzlifah, Figueiredo, Francisco, Armstrong, Lyle, Lako, Majlinda“…RESULTS: scRNA-Seq analysis of 21,343 cells from four adult human corneas and adjacent conjunctivas revealed the presence of 21 cell clusters, representing the progenitor and differentiated cells in all layers of cornea and conjunctiva as well as immune cells, melanocytes, fibroblasts, and blood/lymphatic vessels. …”
Publicado 2021
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1227por Di Prima, Giulia, Licciardi, Mariano, Bongiovì, Flavia, Pitarresi, Giovanna, Giammona, GaetanoEnlace del recurso
Publicado 2021
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1228
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1229por Alvarez, Bernardo V., Piché, Marilyse, Aizouki, Carolin, Rahman, Fariha, Derry, Jonathan M. J., Brunette, Isabelle, Casey, Joseph R.“…Cornea expressed 13,173 genes, which were rank-ordered for their abundance. …”
Publicado 2021
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1230“…Here we used a CRISPR/Cas9 system to study the effect of basigin loss in a human cornea model of squamous epithelial differentiation. …”
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1231por Almubrad, Turki, Mencucci, Rita, Smedowski, Adrian, Samivel, Ramachandran, Almutleb, Essam, Alkanaan, Aljoharah, Khan, Adnan Ali, Masmali, Ali, Akhtar, Saeed“…Three untreated corneas were used as controls (G0). After the CXL procedure, the corneas were processed for electron microscopy. …”
Publicado 2021
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1232“…One such therapy is the use of corneal implants derived from porcine corneas (Xenia(®), Gebauer Medizintechnik GmbH, Neuhausen, DE). …”
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1233por Phithakrotchanakoon, Chitwadee, Mayteeworakoon, Sermsiri, Siriarchawatana, Paopit, Kitikhun, Supattra, Harnpicharnchai, Piyanun, Wansom, Supaporn, Eurwilaichitr, Lily, Ingsriswang, Supawadee“…After co-cultivation of A. cornea TBRC 12900 and P. mangrovi TBRC-BCC 42794, 1,616 proteins were detected including 578 proteins of A. cornea origin and 1,038 proteins of P. mangrovi origin. …”
Publicado 2022
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1234por Jadidi, Khosrow, Mosavi, Seyed Aliasghar, Nejat, Farhad, Aghamolaei, Hosein, Pirhadi, Shiva“…Excellent structural support and stability of the cornea were observed immediately post-operatively and 12 months after surgery. …”
Publicado 2022
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1236por Wilson, Steven E.“…Mesenchymal cells (keratocytes, corneal fibroblasts, and myofibroblasts), as well as mesenchymal progenitor bone marrow-derived fibrocytes, are the major cellular contributors to stromal fibrosis after injury to the cornea. Corneal fibroblasts, in addition to being major progenitors to myofibroblasts, also have anti-fibrotic functions in (1) the production of non-basement membrane collagen type IV that binds activated transforming growth factor (TGF) beta-1 and TGF beta-2 to downregulate TGF beta effects on cells in the injured stroma, (2) the production of chemokines that modulate the entry of bone marrow-derived cells into the stroma, (3) the production of hepatocyte growth factor and keratinocyte growth factor to regulate corneal epithelial healing, (4) the cooperation with the epithelium or corneal endothelium in the regeneration of the epithelial basement membrane and Descemet’s membrane, and other functions. …”
Publicado 2022
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1238
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1239“…This research developed a robust bioinformatics annotation pipeline of HPs from Vittaforma corneae, a clinically important microsporidian that causes ocular infections in immunocompromised individuals. …”
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1240por Somayajulu, Mallika, McClellan, Sharon A., Wright, Robert, Pitchaikannu, Ahalya, Croniger, Bridget, Zhang, Kezhong, Hazlett, Linda D.“…In PM(10)-exposed corneas, SKQ1 restored GSH and Nrf2 levels and lowered MDA. …”
Publicado 2023
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