“…The breakthrough experiments demonstrate the good actual separation ability of NUM-14a for C(2)H(2)/CO(2) and C(2)H(2)/C(2)H(4) mixtures. Furthermore, Grand Canonical Monte Carlo simulations indicate that the pore surface of the NUM-14a has a stronger affinity to preferentially bind C(2)H(2) over CO(2) and C(2)H(4) via stronger C-H···O hydrogen bond interactions. …”
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“…Functional enrichment analysis revealed several canonical pathways to be enriched in CD, including the interleukin-17 signaling pathway, tumor necrosis factor signaling pathway, cytokine–cytokine receptor interaction, toll-like receptor signaling pathway, and nod-like receptor signaling pathway. …”
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“…We report the first in vivo analysis of a canonical CP12 regulatory protein, namely the unique CP12 of the model cyanobacterium Synechocystis PCC 6803, which has the advantage of being able to grow photoautotrophically, photomixotrophically, and photoheterotrophically. …”
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“…The GO biological processes enriched by DEGs mainly involved actin cytoskeleton organization, positive regulation of NF-κB signaling pathway, and positive regulation of canonical Wnt signaling pathway. The DEGs were significantly enriched in cytoplasm, nucleus and cytosol. …”
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“…The occurrence of autophagy was dominated by microtubule-associated protein 1A/1B-light chain 3- (LC3-) associated phagocytosis accompanied by canonical autophagy. A negative correlation exists between the clearance of RBCs by THP-1 cells and the degree of autophagy. …”
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“…In a very recent study, making full use of a zebrafish model in both high-throughput behavioral tracking and live neuroimaging, we explored the potential developmental neurotoxicity of Cd(2+) at environmentally relevant levels and identified multiple connections between Cd(2+) exposure and neurodevelopmental disorders as well as microglia-mediated neuroinflammation, whereas the underlying neurotoxic mechanisms remained unclear. The canonical Wnt/β-catenin signaling pathway plays crucial roles in many biological processes including neurodevelopment, cell survival, and cell cycle regulation, as well as microglial activation, thereby potentially presenting one of the key targets of Cd(2+) neurotoxicity. …”
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“…Our previous study found that T96 could inhibit TNBC invasion via suppressing the canonical and noncanonical TGF-β signaling pathways. …”
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“…This pathway replaces the canonical LS with two proteins, LipS1 and LipS2, which act together to catalyze formation of the lipoyl cofactor. …”
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“…This study investigates the relationship of CPB, consisting of four discrete practices (embodied somatic-observing, non-reactive mindfulness, self-compassion, and compassion for others), with multiple dimensions of well-being. As with other canonical lifestyle behaviors, multiple contemplative practices can be integrated into one’s daily routine. …”
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“…The subsequent functional assessment using a TOP-flash/FOP-flash luciferase reporter system demonstrated that KDF1 variants suppressed the activation of canonical Wnt signaling in 293T cells. To comprehensively investigate the KDF1-related oral morphological anomalies, we performed scanning electron microscopy and ground section of the lower right lateral deciduous incisor extracted from #285 proband, and histopathological assessment of the gingiva. …”
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“…In the present work, high-throughput screening of 2932 Computation-Ready Experimental MOFs (CoRE MOFs) was carried out for ammonia capture from H(2)/N(2)/NH(3) mixtures by Grand Canonical Monte Carlo (GCMC) simulations. It was found that the high-performing MOFs are characterized by tube-like channels, moderate LCD (largest cavity diameter) (4–7.5 Å), and high Q(st)(0)(NH(3)) (the isosteric heat of NH(3) adsorption) (>45 kJ/mol). …”
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“…Additionally, the contents of 5mdC and canonical nucleosides could be obtained at the same time. …”
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“…While crossovers preserve homolog conjunction until anaphase I during canonical meiosis, an alternative system is used in dipteran males. …”
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“…WES identified three novel heterozygous mutations in the TNFAIP3 gene, including a novel splicing mutation located in the canonical splicing site (c.634+2T>C) resulting in an intron 4 insertion containing a premature stop codon, a de novo novel copy number variation (exon 7–8 deletion) and a novel nonsense mutation c.1300_1301delinsTA causing a premature stop codon. …”
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“…Treatment with a short peptide that can shift the dynamic equilibrium favoring the WT conformation of P53, specifically eliminated preL-HSPC that had dysfunctional canonical P53 pathway activity as reflected by single cell RNA sequencing. …”
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“…A hierarchical cluster analysis and a canonical discriminant analysis were introduced to interpret the results of the multi-pattern fingerprint. …”
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“…A role for DDX3X in translational reprogramming during cellular stress is emerging, where it may be involved in the regulation of stress granule formation and in mediating non-canonical translation initiation. Finally, we also discuss the role of DDX3X-mediated translation regulation during viral infections. …”
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