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  1. 21761
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    Hematology and Blood Chemistry Reference Values of Captive Adult Black-Faced Ibis (Theristicus melanopis melanopis)
  2. 21762
    “…Using human PC-3 prostate cancer cells as a canonical model, free ASO and ASO encapsulated into either liposomes or anti-Her2 immunoliposomes were tested for efficacy in vitro using 2D and 3D spheroid models. …”
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    Enhanced Antisense Oligonucleotide Delivery Using Cationic Liposomes Grafted with Trastuzumab: A Proof-of-Concept Study in Prostate Cancer
  3. 21763
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    Quillaja saponaria (Molina) Extracts Inhibits In Vitro Piscirickettsia salmonis Infections
  4. 21764
    “…We demonstrate by single-cell RNASequencing analysis that a sub-fraction of surviving BMPR1B(+) leukemic stem cells are co-enriched in BMP signaling, quiescence and stem cell signatures, without modulation of the canonical BMP target genes, but enrichment in actors of the Jak2/Stat3 signaling pathway. …”
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    The quiescent fraction of chronic myeloid leukemic stem cells depends on BMPR1B, Stat3 and BMP4-niche signals to persist in patients in remission
  5. 21765
    “…Activation of inflammasomes by microbial or host ligands results in cleavage of caspase‐1 (canonical pathway) or caspase‐11 (noncanonical pathway), release of interleukin (IL)‐1β, IL‐18, high mobility group box 1 (HMGB1), and inflammatory cell death known as pyroptosis. …”
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    Interferon Type I Regulates Inflammasome Activation and High Mobility Group Box 1 Translocation in Hepatocytes During Ehrlichia‐Induced Acute Liver Injury
  6. 21766
    “…Subsequently, L(1)-norm regularized sparse canonical correlation analysis and sparse logistic regression are used to identify discriminative connections and Support Vector Machine is trained to realize three two-category classifications. …”
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    Less Is Better: Single-Digit Brain Functional Connections Predict T2DM and T2DM-Induced Cognitive Impairment
  7. 21767
    “…As a mechanism, we found increased levels of sphingomyelin and secretion of the sphingosine 1-phosphate, and the activation of the associated sphingolipid pathway and the non-canonical NF-ĸB pathway, respectively. Moreover, decreasing sphingosine 1-phosphate levels (S1P) by FTY720 (Fingolimod) impaired acid-induced tumor survival and migration. …”
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    Exploring Metabolic Adaptations to the Acidic Microenvironment of Osteosarcoma Cells Unveils Sphingosine 1-Phosphate as a Valuable Therapeutic Target
  8. 21768
    “…The diagnosis of impaired fasting glucose (IFG), condition of prediabetes, as well as that of T2DM was assessed according to canonical guidelines. The TyG Index predicted NAFLD presence in both groups (p = 0.000), but the BCa group showed a major percentage of NAFLD cases with respect to no Ca BD group (59% versus 40%). …”
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    Association of NAFLD and Insulin Resistance with Non Metastatic Bladder Cancer Patients: A Cross-Sectional Retrospective Study
  9. 21769
    “…Moreover, the DFCA classification systematically outperformed canonical connectivity approaches (including both static and linear dynamic connectivity). …”
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    Dynamic brain fluctuations outperform connectivity measures and mirror pathophysiological profiles across dementia subtypes: A multicenter study
  10. 21770
    “…From these results, we demonstrated that DKK3 might contribute to cellular proliferation, invasion, migration, and tumor cell survival in HNSCC cells through a mechanism other than the canonical Wnt signaling pathway, which might be attributed to PI3K–Akt signaling.…”
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    DKK3 Overexpression Increases the Malignant Properties of Head and Neck Squamous Cell Carcinoma Cells
  11. 21771
    “…Pathway analysis identified Nrf2-mediated response as the top canonical pathway. Conclusion: Our results provide key evidence on the therapeutic potential of isolated mitochondria - restoring both brain structure and function, their capability to enter brain meninges and parenchyma upon nasal delivery and undergo rapid cellular internalization and alter the hippocampal transcriptome. …”
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    Nasal administration of mitochondria reverses chemotherapy-induced cognitive deficits
  12. 21772
    “…This study identifies a novel role for ces-1 in regulating glutamatergic behavior that appears to be independent of its canonical role in regulating cell death in the NSM cell lineage.…”
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    The Snail transcription factor CES-1 regulates glutamatergic behavior in C. elegans
  13. 21773
    “…The phantom was scanned on four CT scanners (Philips, Canon, GE, and Siemens) to assess reproducibility. …”
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    Identification of robust and reproducible CT‐texture metrics using a customized 3D‐printed texture phantom
  14. 21774
    “…We strive for conclusions that are general for various DFT functionals, although for macrocycles with up to 20 π-electrons in their main conjugation paths we find that for their T(1) states single-point energies at both canonical UCCSD(T) and approximative DLPNO-UCCSD(T) levels are lowest when based on UB3LYP over UM06-2X and UCAM-B3LYP geometries. …”
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    Triplet State Baird Aromaticity in Macrocycles: Scope, Limitations, and Complications
  15. 21775
    “…β-Catenin is a key molecule of canonical Wnt/β-catenin pathway. Its roles and expression profiles in T cells of tuberculosis (TB) remain unclear. …”
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    The Role of β-Catenin in Th1 Immune Response against Tuberculosis and Profiles of Expression in Patients with Pulmonary Tuberculosis
  16. 21776
    “…Behavioral results showed greater accuracy for canonical SVO and SR sentence types than for noncanonical OR and PAS sentence types, which aligns with prior studies. …”
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    Use of Functional Near Infrared Spectroscopy to Assess Syntactic Processing by Monolingual and Bilingual Adults and Children
  17. 21777
    “…TP estimates were calculated based on stable isotope analysis of bulk (SIA) and compound-specific isotope analysis (CSIA-AA) of the canonical source and trophic amino acids. Mean TP based on SIA was 4.9 ± 1.0 and mean TP based on CSIA-A was 3.9 ± 0.2. …”
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    Yellowfin tuna (Thunnus albacares) foraging habitat and trophic position in the Gulf of Mexico based on intrinsic isotope tracers
  18. 21778
    “…In this study, we present a patient harboring three tumor foci with distinct genetic alterations (AGK-BRAF, RET/PTC3 and an absence of canonical alterations) that were investigated for DNA structure and telomere-related genomic instability. …”
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    A Multifocal Pediatric Papillary Thyroid Carcinoma (PTC) Harboring the AGK-BRAF and RET/PTC3 Fusion in a Mutually Exclusive Pattern Reveals Distinct Levels of Genomic Instability and Nuclear Organization
  19. 21779
    “…Consequently, environmental variables can be used as reference points to classify the Iberian farms according to the type of fattening. Furthermore, canonical correlation analysis allowed to study the relationships between both sets of variables, showing that environmental values had a strong correlation with technical-economic variables. …”
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    Analysis of the Sustainability of Fattening Systems for Iberian Traditional Pig Production through a Technical and Environmental Approach
  20. 21780
    “…A lower diversity index was observed in pyrene-spiked soils. Canonical correspondence analysis (CCA) showed a possible linkage with plant growth attributes and available nitrogen content that influences diversity and abundance of the bacterial community.…”
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    Rhizodegradation of Pyrene by a Non-pathogenic Klebsiella pneumoniae Isolate Applied With Tagetes erecta L. and Changes in the Rhizobacterial Community
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