Mostrando 2,161 - 2,180 Resultados de 23,561 Para Buscar '"canonization"', tiempo de consulta: 0.20s Limitar resultados
  1. 2161
    “…BACKGROUND: The canonical and non-canonical nuclear factor-kappaB (NF-κB) signaling pathways have key roles in cancer, but studies have previously evaluated only the association of canonical transcription factors and ovarian cancer survival. …”
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  2. 2162
    “…Importantly, we show that TOP2-induced genome instability is mediated by mutagenic canonical non-homologous end joining whereas homologous recombination protects cells against these insults. …”
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  3. 2163
    “…BACKGROUND/AIMS: To investigate an effect of ML204 (an inhibitor of transient receptor potential canonical 4 and 5 [TRPC4/5] channels) on interstitial cells of Cajal (ICCs) and therefore determine whether TRPC4/5 channels act on ICC-generated pacemaker activity. …”
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  4. 2164
  5. 2165
    “…Therefore, these newly identified asparagine residues within non-canonical motifs add to those previously reported in canonical sites and suggest that N-glycosylation of Ca(v)3.2 may also occur at non-canonical motifs to control expression of the channel in the plasma membrane. …”
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  6. 2166
    “…Using GD-induced pluripotent stem cell (iPSC)-derived neuronal progenitor cells (NPCs), we have previously reported that neuronal cells have neurodevelopmental defects associated with the downregulation of canonical Wnt signaling. In this study, we report that GD NPCs display elevated levels of Dkk1, which is a secreted Wnt antagonist that prevents receptor activation. …”
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  7. 2167
  8. 2168
    “…Here, we show that Ror2-mediated non-canonical Wnt signaling in the dental mesenchyme plays a crucial role in cell proliferation, and thereby regulates root development size in mouse molars. …”
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  9. 2169
    “…Interestingly, CD10 regulates ASC’s adipogenic maturation non-canonically by modulating endogenous lipolysis without affecting the classical peroxisome proliferator-activated receptor gamma (PPARγ)-dependent adipogenic pathways. …”
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  10. 2170
  11. 2171
    “…Compared to the previously reported bile-cholangiocyte organoids cultured in canonical Wnt-stimulation conditions, ncBCOs have superior function of cholangiocyte ion channels and are able to respond to secretin and somatostatin. …”
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  12. 2172
  13. 2173
  14. 2174
    “…These data do not support the hypothesis about IFNL4-specific non-canonical signaling and point out that functional studies conducted with tagged interferons should be interpreted with caution.…”
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  15. 2175
  16. 2176
    “…Our data also revealed a type of non-canonical Group II introns, with a deviant secondary structure and intronic ORFs lacking known splicing or mobility domains. …”
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  17. 2177
    por Grossberg, Stephen
    Publicado 2021
    “…Specializations of a canonical laminar network of bottom-up, horizontal, and top-down pathways carry out multiple kinds of biological intelligence across different neocortical areas. …”
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  18. 2178
  19. 2179
  20. 2180
    “…GPR133 (ADGRD1), an adhesion G protein–coupled receptor (GPCR) whose canonical signaling activates G(αS)-mediated generation of cytosolic cAMP, has been shown to be necessary for the growth of glioblastoma (GBM), a brain malignancy. …”
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