“…However, RBPJL can bind to canonical RBPJ DNA elements and shows migration dynamics comparable to that of RBPJ in the nuclei of living cells. …”
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“…Nevertheless, patients did not show any apparent disruption of functional connectivity within canonical functional networks. Understanding how tumour infiltration and coupling are related to patients’ recovery represents a major step forward in prognostic development.…”
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“…Using the TCGA-STAD dataset, we performed a differential gene expression analysis between GC samples in upper and lower tertiles of TRPV2 expression, and then through a gene set analysis, we highlighted the enriched ontology and canonical pathways. We used qRT-PCR to assess TRPV2 expression in three GC cell lines and flow cytometry to evaluate cisplatin-induced cell death rates. …”
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“…Next, the presence of any genetic sub-populations was examined using multivariate analytical methods, including canonical discriminant analysis (CDA) and ascending hierarchical clustering (AHC). …”
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“…We first address this by performing direct numerical simulations of the complex interactions between turbulent blood flow in a canonical ascending aorta model and dynamic valve motion in 29 cases with healthy and stenotic valves. …”
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“…Although the participants were aware of the negative effects on their own health and on the environment caused by the application of pesticides in use, the protection measures by individual equipment were insufficient. A canonical analysis indicates that these behaviors were influenced by the farming experience, the benefit of the agricultural council services, the follow-up of training, and the education level. …”
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“…Standard economic indicators provide an incomplete picture of what we value both as individuals and as a society. Furthermore, canonical macroeconomic measures, such as GDP, do not account for non-market activities (e.g., cooking, childcare) that nevertheless impact well-being. …”
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“…Further analysis of these DEGs, including core analysis, upstream analysis, and interaction network analysis, was performed by Ingenuity Pathway Analysis (IPA). The main canonical pathways involved were SPINK1 Pancreatic Cancer Pathway (−log (P value) = 4.45, ratio = 0.0667) and Circadian Rhythm Signaling (−log (P value) = 2.33, ratio = 0.0606). …”
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“…The classification accuracies for all the possible cases of electrode location shifts for various channel configurations (1–3 channels) were calculated using five training-free SSVEP classification algorithms, i.e., the canonical correlation analysis (CCA), extended CCA, filter bank CCA, multivariate synchronization index (MSI), and extended MSI (EMSI). …”
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“…In post-stroke aphasia, language tasks recruit a combination of residual regions within the canonical language network, as well as regions outside of it in the left and right hemispheres. …”
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“…These hesitations are based on current canonical concepts developed for non-physiological application of miRNAs alone, or artificial non-quantitative genetic expression. …”
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“…These effects, together with the concomitant reduction of canonical WNT signaling induced by miR-181a mimic, were in accordance with the effects expected by the loss of RSPO2, thus indicating the causative link between miR-181a and RSPO2. …”
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“…Protein sequence and phylogenetic analyses indicated that LIMLP_05620 displayed all the canonical PerR amino acid residues and is restricted to pathogenic Leptospira clades. …”
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“…CONCLUSION: Even in the presence of systemic immunosuppression and regardless of presence/absence of cystic fibrosis, core canonical components of the host response to infection and rejection are seen. …”
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“…The adsorption capacities of different pore parameters and functional groups were calculated by Grand Canonical Monte Carlo simulation and density functional theory. …”
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“…Here, we used multiset canonical correlation and joint independent component analysis (mCCA + jICA) to fuse MRI data to examine the shared and specific multimodal features between the patients and healthy controls (HCs) and between the responders and non-responders. …”
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“…The alpha subtype of Sonic hedgehog-driven MB is resistant to therapy (including smoothened inhibitors) due to activation of genes from the non-canonical SHH pathway, such as MYCN, YAP1, or TP53. …”
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“…Conversely, Posiphen did not bind the IRP1/IRE complex of mRNAs with canonical IREs, and the translation of these mRNAs was not affected by Posiphen. …”
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“…In order to analyze the thermodynamic and phase formation properties, we construct a composition–temperature phase diagram using a computational sampling by density functional theory, cluster expansion, and semi-grand canonical Monte Carlo methods. The results indicate finite thermodynamic limits of possible Mn concentrations in this system, which are primarily determined by the phase separation into stoichiometric Na(3)MnTi(PO(4))(3) (x = 1.0) and NaTi(2)(PO(4))(3) for x < 1.0 or NaMnPO(4) for x > 1.0. …”
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“…Though PKS systems often act in a predictable co-linear sequence, this BGC includes multiple trans-acting enzymatic domains, a non-canonical condensation termination domain, a bacterial luciferase-like monooxygenase (LLM), and is found in multiple copies within the metagenome-assembled genome (MAG). …”
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