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  1. 22541
    “…Six of the eight TTs contained the putative polyadenylation signals that were overlaps of either canonical AAUAAA or AAUAAA-like polyadenylation signals and AUGAAU, a top-ranking-hexamer of rice and Arabidopsis gene near-upstream regions. …”
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    Transcription Terminator-Mediated Enhancement in Transgene Expression in Maize: Preponderance of the AUGAAU Motif Overlapping With Poly(A) Signals
  2. 22542
    “…ADAMTS-7 reduced the inhibitory capacity of TIMP-1 at its canonical target matrix metalloprotease 9 (MMP-9). …”
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    ADAMTS-7 modulates atherosclerotic plaque formation by degradation of TIMP-1
  3. 22543
    “…Although the original and canonical member of this family is FcγRIIB, more recent studies defined PD1 as an inhibitory receptor that constrains T cell immunity to tumors. …”
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    Inhibitory Receptor Trap: A Platform for Discovery of Inhibitory Receptors That Utilize Inositol Lipid and Phosphotyrosine Phosphatase Effectors
  4. 22544
    “…These mutations include an unusual pattern of uracil-to-cytosine hypermutations and other mutations resulting in the generation of premature stop codons or disruption of the canonical stop codon. The mumps virus SH protein may serve as a virulence factor, based on evidence that it inhibits apoptosis and innate immune signaling in vitro and that recombinant viruses that do not express the SH protein are attenuated in an animal model. …”
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    Functional Characterization of Circulating Mumps Viruses with Stop Codon Mutations in the Small Hydrophobic Protein
  5. 22545
    “…Somatostatin (SRIH) had no effects on both tshβ paralogs, while it exerted a canonical inhibitory effect on gh transcript levels. …”
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    Differential Regulation of the Expression of the Two Thyrotropin Beta Subunit Paralogs by Salmon Pituitary Cells In Vitro
  6. 22546
    “…Thus, despite the apparent maintenance of its barrier function, canonical metabolite transporters are missing in this membrane. …”
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    The Puzzle of Metabolite Exchange and Identification of Putative Octotrico Peptide Repeat Expression Regulators in the Nascent Photosynthetic Organelles of Paulinella chromatophora
  7. 22547
    “…Taken together, this suggests that cortex features a canonical functional microcircuit that supports region-specific information processing. …”
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    Stimulus Feature-Specific Information Flow Along the Columnar Cortical Microcircuit Revealed by Multivariate Laminar Spiking Analysis
  8. 22548
    “…Replicating prior work, sustained effects associated with autobiographical recall periods (which are insensitive to the moment-to-moment content of retrieval) fell primarily within canonical default network regions. Spoken descriptions were rich in episodic details, frequently focusing on physical entities, their ongoing activities, and their appearances. …”
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    Dynamic Content Reactivation Supports Naturalistic Autobiographical Recall in Humans
  9. 22549
    “…Our results showed: (i) a high activity on RNA splicing that can lead to subsequent platelets education; (ii) enrichment of specific modified forms (isomiRs) of canonical miRNAs; and (iii) inhibition of SPARC transcription by specific class of isomiRs. …”
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    Omics Analysis of Educated Platelets in Cancer and Benign Disease of the Pancreas
  10. 22550
    “…RESULTS: The complete circular mitogenome of O. rhinoceros is 20,898 bp in length, with a gene content canonical for insects (13 PCGs, two rRNA genes, and 22 tRNA genes), as well as one structural variation (rearrangement of trnQ and trnI) and a long control region (6,204 bp). …”
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    The complete mitochondrial genome sequence of Oryctes rhinoceros (Coleoptera: Scarabaeidae) based on long-read nanopore sequencing
  11. 22551
    “…For this purpose, a reduced pool of VOCs was selected by 3 multivariate statistical techniques (stepwise discriminant analysis, canonical discriminant analysis and discriminant analysis) to classify hams according to ripening (<12 months) or seasoning (≥12 months) periods and also to seasoning length (S12, S14, S16, or S18 months). …”
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    Characterization of Subcutaneous Fat of Toscano Dry-Cured Ham and Identification of Processing Stage by Multivariate Analysis Approach Based on Volatile Profile
  12. 22552
    “…The results indicated that the variation range of root traits in pot environment was larger than that in hydroponic environment, and canonical coefficients were the greatest between OHC and OPC (0.86) than those in other two groups, namely, IHC vs. …”
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    Genome-Wide Association Study on Seminal and Nodal Roots of Wheat Under Different Growth Environments
  13. 22553
    “…Here, we demonstrate that both the shorter transcript (Tet1(S)) encoding an N-terminally truncated TET1 protein and a full-length Tet1 (Tet1(FL)) transcript encoding canonical TET1 are co-expressed in the adult mouse brain. …”
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    Tet1 Isoforms Differentially Regulate Gene Expression, Synaptic Transmission, and Memory in the Mammalian Brain
  14. 22554
    “…A dendrogram based on unweighted neighbor-joining method clustered all the A. retroflexus L. and C. album L. into two main clusters and four sub-clusters. Canonical correlation analysis (CCA) was used to evaluate relationships between climate classification of origin and traits. …”
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    Redroot Pigweed (Amaranthus retroflexus L.) and Lamb’s Quarters (Chenopodium album L.) Populations Exhibit a High Degree of Morphological and Biochemical Diversity
  15. 22555
    “…We also acquired physical variables measuring objective fitness levels, 7 d physical activity, body mass index, heart rate, and blood pressure. Using canonical correlation analysis, we unravel a latent mode of brain–physical covariation, independent of demographics, school, or socioeconomic status. …”
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    Multimodal Imaging Brain Markers in Early Adolescence Are Linked with a Physically Active Lifestyle
  16. 22556
    “…The aim of this investigation was to immunohistochemically localize the distribution of canonical cannabinoid receptor type 1 (CB1R) and type 2 (CB2R) and the cannabinoid-related receptors transient potential vanilloid receptor 1 (TRPV1), transient potential ankyrin receptor 1 (TRPA1), and serotonin receptor 5-HT1a (5-HT1aR) in the myenteric plexus (MP) of pig ileum. …”
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    Cannabinoid and Cannabinoid-Related Receptors in the Myenteric Plexus of the Porcine Ileum
  17. 22557
    por Stefanich, Sara, Cabrelli, Jennifer
    Publicado 2021
    “…This crosslinguistic disparity presents potential difficulty for L1 English speakers due to L1 segmental and phonotactic constraints; the closest English approximation is the heterosyllabic sequence /nj/ (e.g., “canyon” /kænjn/ ['k(h)æn.jn], cf. Spanish cañón “canyon” /kaɲon/ [ka.'ɲon]). With these crosslinguistic differences in mind, we ask: (1a) Do L1 English learners of L2 Spanish produce acoustically distinct Spanish /n/ and /ɲ/ and (1b) Does the distinction of /n/ and /ɲ/ vary by proficiency? …”
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    The Effects of L1 English Constraints on the Acquisition of the L2 Spanish Alveopalatal Nasal
  18. 22558
    por Qin, Xu-ke, Du, Yang, Liu, Xiu-heng, Wang, Lei
    Publicado 2021
    “…Hence, we hope to investigate the impact of non-canonical function of LSD1 on PCa cell survival. We over-expressed FBXW7 gene through plasmid vector in LNCaP and PC3 cell lines and the result shows that up-regulated FBXW7 can suppress the viability of PC cell through suppressing oncoproteins, such as c-MYC, NOTCH-1. …”
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    LSD1 Promotes Prostate Cancer Cell Survival by Destabilizing FBXW7 at Post-Translational Level
  19. 22559
    “…Data were analysed using canonical correlation, hierarchical clustering and factor analysis techniques to produce five groups of men. …”
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    Targeting interventions for HIV testing and treatment uptake: An attitudinal and behavioural segmentation of men aged 20–34 in KwaZulu-Natal and Mpumalanga, South Africa
  20. 22560
    “…Our data show the extent of carbapenem-resistance far beyond the canonical species Acetinobacter baumannii, Klebsiella pneumoniae or Pseudomonas aeruginosa. …”
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    The extent of carbapenemase-encoding genes in public genome sequences
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