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  1. 2481
    “…CD20(hi) areas lacked canonical germinal centers, as defined by staining for IgD(-)Ki67(+)cells. …”
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    HIV-1 infected humanized DRAGA mice develop HIV-specific antibodies despite lack of canonical germinal centers in secondary lymphoid tissues
  2. 2482
    por Bloom, Harold
    Publicado 2009
    Libro
    Cuentos y cuentistas : el canon del cuento /
  3. 2483
    por Bloom, Harold
    Publicado 2010
    Libro
    Ensayistas y profetas : el canon del ensayo
  4. 2484
    por Baribaud, G, Burla, P
    Publicado 1984
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    Compte rendu de la réunion du 17/9/1984 sur le contrôle des canons V et W du LPI
  5. 2485
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    Wire coating analysis using Phan–Thien–Tanner fluid subject to Lorentz force as a polymer coating material in a canonical covering die
  6. 2486
    “…Between-treatment results showed a 12% increase in interleukin-1 receptor agonist (IL-1Ra) in the treatment group, whereas within-treatment results showed 23% and 7% increases in interleukin-6 (IL-6) and total antioxidant status (TAS), respectively. The first canonical correlation coefficient (r = 0.72) between inflammation markers and blood lipids indicated a positive association between high-sensitivity C-reactive protein (hsCRP) and IL-1Ra with LDL-C and a negative association with HDL-C that explained 62% of the variability in the biomarkers. …”
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    Effect of the Fermented Soy Q-CAN(®) Product on Biomarkers of Inflammation and Oxidation in Adults with Cardiovascular Risk, and Canonical Correlations between the Inflammation Biomarkers and Blood Lipids
  7. 2487
    “…RNA sequencing and Ingenuity Pathway Software Analysis (IPA) of the transcriptomic data revealed several upregulated and downregulated gene expressions along with novel core canonical pathways including Sirtuin signaling, Oxidative Phosphorylation and Mitochondrial dysfunction events involved in EMT changes of the TNBC cells.…”
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    Analysis of Differential Gene Expression and Core Canonical Pathways Involved in the Epithelial to Mesenchymal Transition of Triple Negative Breast Cancer Cells by Ingenuity Pathway Analysis
  8. 2488
    “…While most of the spacers present in bacterial populations that survive phage infection target protospacers flanked by NGG sequences, there is a small fraction that target non-canonical PAMs. Whether these spacers originate through accidental acquisition of phage sequences and/or provide efficient defense is unknown. …”
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    Rarely acquired type II-A CRISPR-Cas spacers mediate anti-viral immunity through the targeting of a non-canonical PAM sequence
  9. 2489
    “…Analysis of genomic and expression data combined with evolutionary information suggested that the human HELZ2 protein is produced from an unforeseen non-canonical initiation codon in Hominidae. This unusual property was confirmed experimentally, extending the human protein by 247 residues. …”
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    HELZ2: a new, interferon-regulated, human 3′-5′ exoribonuclease of the RNB family is expressed from a non-canonical initiation codon
  10. 2490
    “…ALSV has a multi-segmented genome organization and is evolutionarily distant from canonical mono-segmented flaviviruses. The virus-encoded methyltransferase (MTase) plays an important role in viral replication. …”
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    Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses
  11. 2491
    “…Here, we revealed new potential roles of RIP1 in controlling WNT/β-catenin canonical signaling to enhance metastasis of colorectal cancer (CRC). …”
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    A novel RIP1-mediated canonical WNT signaling pathway that promotes colorectal cancer metastasis via β -catenin stabilization-induced EMT
  12. 2492
    “…MA-T treatment in odontoblasts decreased sulfation of HSPG and upregulated the expression of dentin sialophosphoprotein (Dspp) and Dentin Matrix Protein 1 (Dmp1) via activation of canonical Wnt signaling in vitro. Ex vivo application of MA-T also enhanced dentin matrix formation in developing tooth explants. …”
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    On-demand chlorine dioxide solution enhances odontoblast differentiation through desulfation of cell surface heparan sulfate proteoglycan and subsequent activation of canonical Wnt signaling
  13. 2493
    por Zhao, Meng, Li, Xiao-Dong, Chen, Zhijian
    Publicado 2010
    “…These results suggest that CC2D1A activates NF-κB through the canonical IKK pathway.…”
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    CC2D1A, a DM14 and C2 Domain Protein, Activates NF-κB through the Canonical Pathway
  14. 2494
    “…Canonical but not non-canonical activation depended on MALT1 paracaspase activity, and expression of E3-inactive c-IAP2 activated non-canonical NF-κB. …”
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    Non-Canonical NF-κB Activation and Abnormal B Cell Accumulation in Mice Expressing Ubiquitin Protein Ligase-Inactive c-IAP2
  15. 2495
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    Expressed Sequence Tags from Cephalic Chemosensory Organs of the Northern Walnut Husk Fly, Rhagoletis suavis, Including a Putative Canonical Odorant Receptor
  16. 2496
    por Kubiak, Jacek Z., El Dika, Mohammed
    Publicado 2011
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    Canonical and Alternative Pathways in Cyclin-Dependent Kinase 1/Cyclin B Inactivation upon M-Phase Exit in Xenopus laevis Cell-Free Extracts
  17. 2497
    “…Wnt5a is one of the so-called non-canonical Wnt ligands which do not act through β-catenin. …”
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    Wnt5a Is Strongly Expressed at the Leading Edge in Non-Melanoma Skin Cancer, Forming Active Gradients, while Canonical Wnt Signalling Is Repressed
  18. 2498
    “…We conclude that signaling via ERK/LRP6 pathway and direct β-catenin phosphorylation at Tyr142 represent two mechanisms used by various receptor tyrosine kinase systems to activate canonical WNT signaling.…”
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    Receptor Tyrosine Kinases Activate Canonical WNT/β-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct β-Catenin Phosphorylation
  19. 2499
    “…Notably, the pool of DsiRNAs caused lower immunostimulation than the pool of canonical siRNAs, whereas the immunostimulation effect was in relation to the length with the single-site siRNAs. …”
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    Enzymatically Produced Pools of Canonical and Dicer-Substrate siRNA Molecules Display Comparable Gene Silencing and Antiviral Activities against Herpes Simplex Virus
  20. 2500
    por Zhu, Y, Casey, P J, Kumar, A P, Pervaiz, S
    Publicado 2013
    “…Taken together, our data highlight the critical role of non-canonical regulation of Rho GTPases and involvement of downstream superoxide-mediated activation of JNK pathway in the anticancer activity of simvastatin, which would have potential clinical implications.…”
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    Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases
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