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“…Genomic imprinting is the monoallelic expression of a gene based on parent of origin and is a consequence of differential epigenetic marking between the male and female germlines. Canonically, genomic imprinting is mediated by allelic DNA methylation. …”
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“…However, almost all canonical shapes found in the world are also highly symmetrical; therefore, it is unclear whether previously reported facilitative effect of canonical organization is really due to canonicality, or simply driven by spatial symmetry. …”
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“…These findings suggest that the progress of large scientific fields may be slowed, trapped in existing canon. Policy measures shifting how scientific work is produced, disseminated, consumed, and rewarded may be called for to push fields into new, more fertile areas of study.…”
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“…This work considers a class of canonical neural networks comprising rate coding models, wherein neural activity and plasticity minimise a common cost function—and plasticity is modulated with a certain delay. …”
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“…Several non-canonical, methylated terpenes have been described as products of genetically modified Escherichia coli recently, and the aroma properties of 28 odor-active methylated derivatives of prenol, isoprenol, bornane, camphene, carene, citronellol, fenchol, geraniol, limonene, linalool, terpineol, and farnesol were characterized for the first time in the current study. …”
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“…We show how a behavioral form of capital theory can be derived using canonical quantization. In particular, we introduce quantum cognition into capital theory by applying Dirac’s canonical quantization approach to Weitzman’s Hamiltonian formulation of capital theory, the justification for the use of quantum cognition being the incompatibility of questions encountered in the investment decision-making process. …”
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“…Canonical strigolactones (SLs), such as orobanchol, consist of a tricyclic lactone ring (ABC-ring) connected to a methylbutenolide (D-ring). …”
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“…An increase in β-catenin and cytosolic DVL-1 levels, indicating a switch from non-canonical to canonical Wnt signaling, is found in the postnatal kidney of yotari mice. …”
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“…These findings reveal that the HSM extract has anti-inflammatory properties attributed to its ability to inhibit both canonical and non-canonical inflammasomes.…”
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“…They are characterized by specific maturation processes defined by canonical and non-canonical biogenic pathways. Analysis of ∼0.5 billion sequences from mouse data sets derived from different tissues, developmental stages and cell types, partly characterized by either ablation or mutation of the main proteins belonging to miRNA processor complexes, reveals 66 high-confidence new genomic loci coding for miRNAs that could be processed in a canonical or non-canonical manner. …”
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“…Furthermore, DYRK1B exerts positive and negative feedback regulation on the Hh pathway itself: It negatively interferes with SMO-elicited canonical Hh signaling, while at the same time it provides positive feed-forward functions by promoting AKT-mediated GLI stability. …”
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“…Here, we report that let-7g reduces macrophage transformation and alleviates foam cell apoptosis by suppressing both canonical and non-canonical NF-κB pathways. In the canonical pathway, let-7g inhibits phosphorylation of IKKβ and IκB, down-regulates SREBF2 and miR-33a, and up-regulates ABCA1. …”
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“…Search for variants in non-canonical and canonical exons 6 was performed by Sanger sequencing. …”
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