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  1. 3061
    por Gong, Tao, Shuai, Lan, Wu, Yicheng
    Publicado 2019
    “…This paper investigates a particular type of non-canonical construction in Mandarin Chinese displaying an apparent semantics-syntax mismatch. …”
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    The acceptability judgment of Chinese pseudo-modifiers with and without a sentential context
  2. 3062
    “…Van Gogh-like (Vangl) and Prickle (Pk) are core components of the non-canonical Wnt planar cell polarity pathway that controls epithelial polarity and cell migration. …”
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    The planar cell polarity protein VANG-1/Vangl negatively regulates Wnt/β-catenin signaling through a Dvl dependent mechanism
  3. 3063
    “…However, some mRNAs are not punctuated by tRNAs, and it remains largely unknown how these non-canonical junctions are resolved. The FASTK family proteins are emerging as key players in non-canonical RNA processing. …”
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    The FASTK family proteins fine-tune mitochondrial RNA processing
  4. 3064
    “…An aggressive subtype of breast cancer, known as triple-negative breast cancer (TNBC), demonstrates dysregulation in canonical and non-canonical Wnt signaling. In this review, we summarize regulators of canonical and non-canonical Wnt signaling, as well as Wnt signaling dysfunction that mediates the progression of TNBC. …”
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    Wnt signaling in triple-negative breast cancer
  5. 3065
    “…A < 0.05 significance level was adopted to select the interpreted canonical functions (CF) and ± 0.40 as canonical load value of the analyzed variables. …”
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    Factors associated with the nutritional status of children less than 5 years of age
  6. 3066
    por Bagby, Grover
    Publicado 2018
    “…Dysfunctions of the canonical and non-canonical pathways that drive stem cell exhaustion and neoplastic clonal selection are reviewed, and the potential therapeutic importance of fully investigating the scope and interdependences of the canonical and non-canonical pathways is emphasized.…”
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    Recent advances in understanding hematopoiesis in Fanconi Anemia
  7. 3067
    “…For each month, we (1) calculated the infants’ canonical babbling ratios with CBR(UTTER), i.e., the ratio of number of utterances containing canonical syllables to total number of utterances, and (2) classified their pre-linguistic vocalisations in three non-canonical and four canonical vocalisation subtypes. …”
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    Vocalisation Repertoire at the End of the First Year of Life: An Exploratory Comparison of Rett Syndrome and Typical Development
  8. 3068
    “…Early-stage cancers exhibit higher canonical MED19 expression than alternative MED19, consistent with canonical MED19’s ability to promote cell proliferation under androgen deprivation. …”
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    MED19 encodes two unique protein isoforms that confer prostate cancer growth under low androgen through distinct gene expression programs
  9. 3069
    “…METHODS: Using combined ChIP-sequencing and microarray analyses, we determined the cistromes and target gene signatures of canonical and non-canonical NF-κB species in Hodgkin lymphoma (HL) cells. …”
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    A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses
  10. 3070
    “…Next, we evaluated the canonical correlations (comparable to an eigenvalue) for each canonical dimension to determine the required number of significant canonical dimensions (or latent constructs) that were necessary to understand the association between the two variable sets. …”
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    4286 The Relationship Between Tinnitus-Related Distress and PTSD Symptoms Among Post 9/11 Veterans with Posttraumatic Headache
  11. 3071
    “…Ischemic pre (IPC)- and post-conditioning (IPO) induce upregulation of the canonical and non-canonical inflammasome regulators. …”
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    Liver Ischemia Reperfusion Injury, Enhanced by Trained Immunity, Is Attenuated in Caspase 1/Caspase 11 Double Gene Knockout Mice
  12. 3072
    “…More importantly, transposed words elicited a more negative N400 amplitude and a less positive LPC amplitude compared with the amplitudes elicited by canonical words for CVF and RVF presentations. For LVF presentations, transposed words elicited a less negative N250 amplitude compared with canonical words, and there was no significant difference between canonical words and transposed words in the N400 effect. …”
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    Electrophysiological Correlates of Character Transposition in the Left and Right Visual Fields
  13. 3073
    “…Chronic inflammation of the colon causes genomic and/or transcriptomic events, which can lead to expression of non-canonical protein sequences contributing to oncogenesis. …”
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    Quantitative Proteogenomic Characterization of Inflamed Murine Colon Tissue Using an Integrated Discovery, Verification, and Validation Proteogenomic Workflow
  14. 3074
    “…MicroRNA targets are often recognized through pairing between the miRNA seed region and complementary sites within target mRNAs, but not all of these canonical sites are equally effective, and both computational and in vivo UV-crosslinking approaches suggest that many mRNAs are targeted through non-canonical interactions. …”
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    Predicting effective microRNA target sites in mammalian mRNAs
  15. 3075
    “…Mechanistically, stabilization of NIK activates NF-κB non-canonical signaling and represses NF-κB canonical signaling. …”
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    Stabilization of NF-κB-Inducing Kinase Suppresses MLL-AF9-Induced Acute Myeloid Leukemia
  16. 3076
    “…This recruitment decreases CUL3-KLHL12-mediated polyubiquitination of Dishevelled, a central intermediate in canonical and non-canonical Wnt signaling. Knock down of PLEKHA4 in mammalian cells demonstrates that PLEKHA4 positively regulates canonical and non-canonical Wnt signaling via these effects on the Dishevelled polyubiquitination machinery. …”
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    PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling
  17. 3077
    “…Many signaling pathways are dysregulated in OC and can activate NF-κB signaling through canonical or non-canonical pathways which have both overlapping and distinct roles in tumor progression. …”
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    NF-κB Signaling in Ovarian Cancer
  18. 3078
    por Nguyen, Ngoc Minh, Cho, Jungsook
    Publicado 2022
    “…In this review, we briefly overview canonical and non-canonical Hh pathways and their inhibitors as targeted cancer therapy. …”
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    Hedgehog Pathway Inhibitors as Targeted Cancer Therapy and Strategies to Overcome Drug Resistance
  19. 3079
    por Law, Samuel M., Zheng, Jie J.
    Publicado 2022
    “…Therefore, caution is required when micromolar levels of CHIR-99021 are used for the purpose of activating the canonical Wnt signaling pathway.…”
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    Premise and peril of Wnt signaling activation through GSK-3β inhibition
  20. 3080
    “…During regeneration, canonical Wnt signalling is activated and has been implicated in regulating myogenic lineage progression and terminal differentiation. …”
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    Wnt/β-catenin controls follistatin signalling to regulate satellite cell myogenic potential
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