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  1. 3101
    “…Autophagy is a cellular innate-immune defence mechanism against intracellular microorganisms, including Mycobacterium tuberculosis (Mtb). How canonical and non-canonical autophagy function to control Mtb infection in phagosomes and the cytosol remains unresolved. …”
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    ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages
  2. 3102
    “…YGJ suppressed the activation of macrophages and then inhibited non-canonical Wnt signaling and promoted canonical Wnt signaling. …”
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    Yiguanjian decoction enhances fetal liver stem/progenitor cell-mediated repair of liver cirrhosis through regulation of macrophage activation state
  3. 3103
    “…To sustain prostate tumorigenicity, EZH2 establishes non-canonical biochemical interaction with AR for mediating oncogene activation, in addition to its canonical role as a transcriptional repressor and enzymatic subunit of Polycomb Repressive Complex 2 (PRC2). …”
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    A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant, promoting oncogene activation and tumorous transformation
  4. 3104
    “…Here, we demonstrate that variant histone H3.3 is essential for Drosophila development only when canonical histone gene copy number is reduced, suggesting that coordination between canonical H3.2 and variant H3.3 expression is necessary to provide sufficient H3 protein for normal genome function. …”
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    Reduced histone gene copy number disrupts Drosophila Polycomb function
  5. 3105
    “…Based on DNA sequence analysis, along with canonical Sarcocystis species present in their respective hosts, non-canonical (atypical) species, such as S. capracanis and S. morae, were detected in sheep, while S. arieticanis and S. tenella were found in goats. …”
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    Sarcocystis Species Richness in Sheep and Goats from Lithuania
  6. 3106
    “…The first canonical axis captured a gradient from crowded, low-income communities with corrugated roof housing to higher-income communities. …”
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    Urban slum structure: integrating socioeconomic and land cover data to model slum evolution in Salvador, Brazil
  7. 3107
    “…In this study, we show that the lymphotoxin β receptor (LTβR) is upregulated in BCa via activation of the canonical and non-canonical nuclear factor-κB (NF-κB) pathways. …”
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    Lymphotoxin β receptor activation promotes bladder cancer in a nuclear factor-κB-dependent manner
  8. 3108
    “…The canonical set of amino acids leads to an exceptionally wide range of protein functionality. …”
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    Residue-specific Incorporation of Noncanonical Amino Acids into Model Proteins Using an Escherichia coli Cell-free Transcription-translation System
  9. 3109
    “…Experimental evidence indicates that about 60% of miRNA-binding activity does not follow the canonical rule about the seed matching between miRNA and target mRNAs, but rather a non-canonical miRNA targeting activity outside the seed or with a seed-like motifs. …”
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    From benchmarking HITS-CLIP peak detection programs to a new method for identification of miRNA-binding sites from Ago2-CLIP data
  10. 3110
    “…We found a cluster of tightly co-occurring antibodies (canonical serologies, containing CCP2), along with several independently expressed antibodies (non-canonical serologies). …”
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    Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype
  11. 3111
    “…Loss-of-function mutation of BLI results in chronic up-regulation of a set of both canonical UPR genes and non-canonical UPR downstream genes, leading to cell death and growth retardation. …”
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    BLISTER-regulated vegetative growth is dependent on the protein kinase domain of ER stress modulator IRE1A in Arabidopsis thaliana
  12. 3112
    “…While preferentially dependent on canonical STING, we demonstrate that genotoxic DNA damage induced by camptothecin (CPT) also drove IL-6 production through non-canonical STING signaling in selected cancer cells. …”
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    Pharmacological Targeting of STING-Dependent IL-6 Production in Cancer Cells
  13. 3113
    por Griffin, Michael J.
    Publicado 2022
    “…This review will focus on the research that has examined canonical and non-canonical NF-κB signaling in adipocytes, focusing on genetic studies that examine loss-of-function of NF-κB specifically in fat cells. …”
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    On the Immunometabolic Role of NF-κB in Adipocytes
  14. 3114
    por Crainic, Marius, Mestre, João Nuno
    Publicado 2017
    “…We present some features of the smooth structure and of the canonical stratification on the orbit space of a proper Lie groupoid. …”
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    Orbispaces as differentiable stratified spaces
  15. 3115
    por Cheltsov, Ivan
    Publicado 2017
    “…We prove that [Formula: see text] and [Formula: see text] are the smallest log canonical thresholds of reduced plane curves of degree [Formula: see text] , and we describe reduced plane curves of degree d whose log canonical thresholds are these numbers. …”
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    Worst Singularities of Plane Curves of Given Degree
  16. 3116
    “…In contrast, it is argued that canonical templates and sequence rules may have reached their peak.…”
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    Disjoint combinations profiling (DCP): a new method for the prediction of antibody CDR conformation from sequence
  17. 3117
    “…We therefore adapted a canonical (repeatable) microcircuit model used in dynamic causal modelling (DCM) previously used to model induced responses in visual cortex. …”
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    Computational modelling of movement-related beta-oscillatory dynamics in human motor cortex()
  18. 3118
    “…Using ultra-deep sequencing the frequency of aberrant and non-canonical splicing events for three splice junctions flanking exon 7 of SMN1 were determined at single nucleotide resolution. …”
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    Ultra-deep sequencing reveals pre-mRNA splicing as a sequence driven high-fidelity process
  19. 3119
    por Lele, Subhash R.
    Publicado 2023
    “…In scientific problems, an appropriate statistical model often involves a large number of canonical parameters. Often times, the quantities of scientific interest are real-valued functions of these canonical parameters. …”
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    Profile Likelihood for Hierarchical Models Using Data Doubling
  20. 3120
    “…We also review the contributions of non-canonical Wnt signaling and other distinct pathways in the tumor micro environment that cross-talk to the canonical Wnt pathway and thereby influence colon cancer progression. …”
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    Wnt signaling and colon carcinogenesis: Beyond APC
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