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3201por Popat, Hashmat, Richmond, Stephen, Zhurov, Alexei I., Rosin, Paul L., Marshall, David“…The first canonical variate was significant in discriminating between the utterances and accounted for 72.8% of the total variance of the model. …”
Publicado 2013
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3202“…In our results, the canonical potential sentences showed a scrambling cost at the second argument position (the nominative argument). …”
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3203“…Canonical Wnt signaling pathway, also known as Wnt/β-catenin signaling pathway, is a crucial mechanism for cellular maintenance and development. …”
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3204por Hughes, Stacie E., Hemenway, Elizabeth, Guo, Fengli, Yi, Kexi, Yu, Zulin, Hawley, R. Scott“…Although the components that comprise the SC are predominantly studied in this canonical ribbon-like structure, they can also polymerize into repeated structures known as polycomplexes. …”
Publicado 2019
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3205“…Lokiretroviruses and canonical retroviruses did not form a monophyletic group, indicating that lokiretroviruses and canonical retroviruses might represent two distinct virus families. …”
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3206“…Furthermore, we demonstrate that the linker region in the C-terminus of WNT7A binds to the FZD7 receptor while it does not activate non-canonical Wnt signaling. However, the hairpin and the linker region of WNT7A can activate canonical Wnt signaling independent of each other suggesting that specificity of downstream signaling might be depending on those specific regions in the C-terminus.…”
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3207“…MicroRNA (miRNA/miR) 5′-isoforms (5′-isomiRs) differ from canonical sequences registered in the microRNA database in the length of their 5′ ends. …”
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3208por Hiraga, Toru, Horibe, Kanji, Koide, Masanori, Yamashita, Teruhito, Kobayashi, Yasuhiro“…Canonical Wnt signaling is also involved in the progression of several types of cancers including breast cancer. …”
Publicado 2023
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3209por Kasurinen, Jussi Herman, Hagström, Jaana, Kaprio, Tuomas, Jalkanen, Sirpa, Salmi, Marko, Böckelman, Camilla, Haglund, Caj“…A high serum bFGF concentration is associated with a favorable prognostic factor among patients with a canonical tumor phenotype. A high PDGF-bb tissue expression is associated with non-metastasized disease and with the immune, canonical, and metabolic subtypes. …”
Publicado 2023
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3210por Joechner, Ann-Kathrin, Hahn, Michael A, Gruber, Georg, Hoedlmoser, Kerstin, Werkle-Bergner, Markus“…The synchronization of canonical fast sleep spindle activity (12.5–16 Hz, adult-like) precisely during the slow oscillation (0.5–1 Hz) up peak is considered an essential feature of adult non-rapid eye movement sleep. …”
Publicado 2023
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3211por Vucic, Domagoj“…Binding of TNF-related weak inducer of apoptosis (TWEAK) to its cognate receptor, FN14, triggers the assembly of receptor-associated signaling complex, which allows the activation of canonical and non-canonical nuclear factor kappa B (NF-κB) as well as mitogen-activated protein kinase signaling pathways. …”
Publicado 2013
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3212por Heilmann, Aline, Schinke, Thorsten, Bindl, Ronny, Wehner, Tim, Rapp, Anna, Haffner-Luntzer, Melanie, Nemitz, Claudia, Liedert, Astrid, Amling, Michael, Ignatius, Anita“…In contrast, little is known about the role of non-canonical Wnt signaling in bone. Recently, it was demonstrated that the serpentine receptor Fzd9, a Wnt receptor of the Frizzled family, is essential for osteoblast function and positively regulates bone remodeling via the non-canonical Wnt pathway without involving β-catenin-dependent signaling. …”
Publicado 2013
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3213por Noort, Ae R, van Zoest, Katinka PM, Weijers, Ester M, Koolwijk, Pieter, Maracle, Chrissta X, Novack, Deborah V, Siemerink, Martin J, Schlingemann, Reinier O, Tak, Paul P, Tas, Sander W“…In endothelial cells (ECs), expression of the pro-angiogenic chemokine CXCL12 is regulated by non-canonical nuclear factor (NF)-κB signalling. Here, we report that NF-κB-inducing kinase (NIK) and subsequent non-canonical NF-κB signalling regulate both inflammation-induced and tumour-associated angiogenesis. …”
Publicado 2014
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3214por Zouein, Fouad A., Altara, Raffaele, Chen, Qun, Lesnefsky, Edward J., Kurdi, Mazen, Booz, George W.“…Our understanding of how the non-canonical genomic and mitochondrial actions of STAT3 in the heart are regulated and coordinated with the canonical actions of STAT3 is rudimentary. …”
Publicado 2015
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3215“…High expression in NC of genes transmitting the signal of Wnt non-canonical signaling cascades leading to activation of AP-1 transcription factor, points to predominant role of non-canonical Wnt signaling in a long term maintenance of NC biological functions. …”
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3216por Carstensen-Kirberg, Maren, Röhrig, Karin, Niersmann, Corinna, Ouwens, D. Margriet, Belgardt, Bengt F., Roden, Michael, Herder, Christian“…This study examined effects of Sfrp5 on (i) beta cell viability and proliferation, (ii) basal and glucose-stimulated insulin secretion and (iii) canonical and non-canonical Wnt signalling pathways. …”
Publicado 2019
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3217por Del Giovane, Alice, Russo, Mariagiovanna, Tirou, Linda, Faure, Hélène, Ruat, Martial, Balestri, Sonia, Sposato, Carola, Basoli, Francesco, Rainer, Alberto, Kassoussi, Abdelmoumen, Traiffort, Elisabeth, Ragnini-Wilson, Antonella“…Since Smo is also able to transduce Shh signals via various non-canonical pathways such as the blockade of Gli1, we addressed the potential of non-canonical Smo signaling to contribute to oligodendroglial cell maturation in myelinating cells using the non-canonical Smo agonist GSA-10, which downregulates Gli1. …”
Publicado 2022
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3218por Maeda, Kazuhiro, Kobayashi, Yasuhiro, Koide, Masanori, Uehara, Shunsuke, Okamoto, Masanori, Ishihara, Akihiro, Kayama, Tomohiro, Saito, Mitsuru, Marumo, Keishi“…The Wnt signaling pathway can be classified into two main pathways: canonical and non-canonical. Of these, the canonical Wnt signaling pathway promotes osteogenesis. …”
Publicado 2019
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3219“…The phosphoprotein Dishevelled (Dsh) is an essential component of Wnt signaling pathways and transduces signals into three separate branches, the canonical, non-canonical and Ca(2+ )pathways. How Dsh focuses signaling into these branches remains mysterious, but a new study reveals the importance of nuclear localization of Dsh for pathway-specific activation.…”
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3220“…In canonical Wnt signaling, Dishevelled (Dvl) is a critical cytoplasmic regulator that releases β-catenin from degradation. …”
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