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3261“…This corresponds to about 20 individuals per variable and is considered sufficient to accurately interpret the largest (i.e., first) canonical correlation. RESULTS: The analysis between the health variables and housing variables set yielded two significant pairs of variates with the canonical correlations 0.68 (p < 0.0001) and 0.33 (p = 0.0112), respectively. …”
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3262por Wang, Weiguang, Song, Buer, Anbarchian, Teni, Shirazyan, Anna, Sadik, Joshua E., Lyons, Karen M.“…TGFβs act through canonical and non-canonical pathways, and canonical signals are transduced via Smad2 and Smad3. …”
Publicado 2016
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3263por Kang, Hee Eun, Seo, Yoojeong, Yun, Jun Seop, Song, Sang Hyun, Han, Dawool, Cho, Eunae Sandra, Cho, Sue Bean, Jeon, Yoon, Lee, Ho, Kim, Hyun Sil, Kang, Joyeon, Yook, Jong In, Kim, Nam Hee, Kim, Tae Il“…We found that Axin2, an authentic target gene of canonical Wnt, acts as aYAP phosphorylation activator in APC-mutated CRC. …”
Publicado 2021
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3264“…Cells presenting peptides with mutated or other non-canonical sequences can be utilized for both targeted therapies and diagnostics. …”
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3265por Distefano, Rosario, Nigita, Giovanni, Le, Patricia, Romano, Giulia, Acunzo, Mario, Nana-Sinkam, Patrick“…Here, we concurrently profiled canonical and non-canonical miRNA molecules in White American (W) and Black or African American (B/AA) lung adenocarcinoma (LUAD) patients from The Cancer Genome Atlas (TCGA) cohort. …”
Publicado 2022
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3266“…Classical theorems are discussed further by applying the Jordan canonical form, the Rayleigh quotient, and simple matrix pencils with late…”
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3267por Buchdahl, H A“…The book covers many areas in thermodynamics such as states and transition; adiabatic isolation; irreversibility; the first, second, third and Zeroth laws of thermodynamics; entropy and entropy law; the idea of the application of thermodynamics; pseudo-states; the quantum-static al canonical and grand canonical ensembles; and semi-classical gaseous systems. …”
Publicado 2013
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3268por O'Hara, Jun“…Energy of knots is a theory that was introduced to create a "canonical configuration" of a knot - a beautiful knot which represents its knot type. …”
Publicado 2003
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3269
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3270“…The Pontocerebellar Hypoplasia 7 (PCH7)-associated 3’ exonuclease TOE1 promotes maturation of canonical small nuclear RNAs (snRNAs). Here, we demonstrate that TOE1 achieves specificity towards canonical snRNAs by recognizing Sm complex assembly and cap trimethylation, two features that distinguish snRNAs undergoing correct biogenesis from other small non-coding RNAs. …”
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3271por Schleussner, Nikolai, Cauchy, Pierre, Franke, Vedran, Giefing, Maciej, Fornes, Oriol, Vankadari, Naveen, Assi, Salam A., Costanza, Mariantonia, Weniger, Marc A., Akalin, Altuna, Anagnostopoulos, Ioannis, Bukur, Thomas, Casarotto, Marco G., Damm, Frederik, Daumke, Oliver, Edginton-White, Benjamin, Gebhardt, J. Christof M., Grau, Michael, Grunwald, Stephan, Hansmann, Martin-Leo, Hartmann, Sylvia, Huber, Lionel, Kärgel, Eva, Lusatis, Simone, Noerenberg, Daniel, Obier, Nadine, Pannicke, Ulrich, Fischer, Anja, Reisser, Anja, Rosenwald, Andreas, Schwarz, Klaus, Sundararaj, Srinivasan, Weilemann, Andre, Winkler, Wiebke, Xu, Wendan, Lenz, Georg, Rajewsky, Klaus, Wasserman, Wyeth W., Cockerill, Peter N., Scheidereit, Claus, Siebert, Reiner, Küppers, Ralf, Grosschedl, Rudolf, Janz, Martin, Bonifer, Constanze, Mathas, Stephan“…IRF4-C99R fundamentally alters IRF4 DNA-binding, with loss-of-binding to canonical IRF motifs and neomorphic gain-of-binding to canonical and non-canonical IRF CEs. …”
Publicado 2023
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3272por Osborn, Daniel P. S., Roccasecca, Rosa Maria, McMurray, Fiona, Hernandez-Hernandez, Victor, Mukherjee, Sriparna, Barroso, Inês, Stemple, Derek, Cox, Roger, Beales, Philip L., Christou-Savina, Sonia“…These data identify FTO as a protein-regulator of the balanced activation between canonical and non-canonical branches of the Wnt pathway. …”
Publicado 2014
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3273“…The accuracy of ClaRNA is 0.997 for canonical base pairs, 0.983 for non-canonical pairs and 0.961 for stacking interactions. …”
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3274por Das, Anish, Banday, Mahrukh, Fisher, Michael A., Chang, Yun-Juan, Rosenfeld, Jeffrey, Bellofatto, Vivian“…The well-studied eukaryotes possess a tandemly repeated 7-amino-acid sequence, called the canonical CTD, which orchestrates various steps in mRNA synthesis. …”
Publicado 2017
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3275por Lee, Ha Neul, Mitra, Mithun, Bosompra, Oye, Corney, David C., Johnson, Elizabeth L., Rashed, Nadine, Ho, Linda D., Coller, Hilary A.“…We show that the short RECK protein competes with matrix metalloprotease 9 (MMP9) for binding to the Kazal motifs of canonical RECK, thus liberating MMP9 from an inactivating interaction with canonical RECK. …”
Publicado 2018
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3276por Vethe, Heidrun, Ghila, Luiza, Berle, Magnus, Hoareau, Laurence, Haaland, Øystein A., Scholz, Hanne, Paulo, Joao A., Chera, Simona, Ræder, Helge“…In this study, we stimulated canonical and non-canonical Wnt signaling in hiPSC-derived S7 cells using syntetic proteins including WNT3A, WNT4, WNT5A and WNT5B, and we inhibited endogenous Wnt signaling with the Tankyrase inhibitor G007-LK (TKi). …”
Publicado 2019
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3277por Conedera, Federica Maria, Quintela Pousa, Ana Maria, Presby, David Mikal, Mercader, Nadia, Enzmann, Volker, Tschopp, Markus“…Our transcriptome analysis showed a different activation of canonical and non-canonical signaling pathways and how they shaped the injury response. …”
Publicado 2020
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3278por Garcia-Rodriguez, Gabriela, Charlier, Daniel, Wilmaerts, Dorien, Michiels, Jan, Loris, Remy“…The antitoxin RnlB binds the canonical HEPN dimer conformation, inhibiting RnlA by blocking access to its active site. …”
Publicado 2021
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3279por Nie, Xiaobo, Liu, Huiyang, Ye, Wenling, Wei, Xiaoyun, Fan, Lili, Ma, Han, Li, Lanqing, Xue, Wanting, Qi, Wenting, Wang, Yan‐Dong, Chen, Wei‐Dong“…The overactivation of canonical Wnt/β‐catenin pathway and the maintenance of cancer stem cells (CSCs) are essential for the onset and malignant progression of most human cancers. …”
Publicado 2022
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3280“…The present study investigated the canonical position of instrumental and locative adverbial phrases in both Japanese sentences and noun phrases to determine whether the canonical positions are parallel. …”
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