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  1. 3421
    “…Overexpression of canonical miR‐34/449 or 5′‐isomiR‐34/449 induces distinct gene expression profiles and biological effects. …”
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    Characterizing isomiR variants within the microRNA‐34/449 family
  2. 3422
    por Cao, Hong-Wen, Yang, Ke-Yu, Yan, Hong-Mei
    Publicado 2017
    “…The results indicate that Chinese readers can identify words with character transpositions in rapid succession; however, a transposition cost is involved in identifying transposed words compared to canonical words. In RSVP reading, character order of words is more likely to be reversed during the period from 30 to 180 ms for canonical and reversible words, but the period from 30 to 240 ms for transposed words. …”
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    Character Decomposition and Transposition Processes of Chinese Compound Words in Rapid Serial Visual Presentation
  3. 3423
    “…Canonical processing of miRNA begins in the nucleus with the Microprocessor complex, which is minimally composed of the RNase III enzyme Drosha and two copies of its cofactor protein DGCR8. …”
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    Engineering double-stranded RNA binding activity into the Drosha double-stranded RNA binding domain results in a loss of microRNA processing function
  4. 3424
    “…[Image: see text] IKKβ plays a central role in the canonical NF-kB pathway, which has been extensively characterized. …”
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    Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related Biomarkers
  5. 3425
    “…Here we report an in vivo Drosophila assay that can be used to distinguish between activation, de-repression and repression of transcriptional responses, separating upstream and downstream pathway activation and canonical/non-canonical Wnt signals in embryos. We find specific sets of genes downstream of both β-catenin and TCF with an additional group of genes regulated by Wnt, while the non-canonical Wnt4 regulates a separate cohort of genes. …”
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    An embryonic system to assess direct and indirect Wnt transcriptional targets
  6. 3426
    “…Inhibition of HIP by lentiviral knockdown activated canonical hedgehog signaling in LEPCs, while it activated non-canonical hedgehog signaling in ECs. …”
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    Hedgehog-Interacting Protein (HIP) Regulates Apoptosis Evasion and Angiogenic Function of Late Endothelial Progenitor Cells
  7. 3427
    “…This results in a representation able to describe planar canonical and non-canonical base pairs and base–phosphate interactions and to distinguish sugar puckers and glycosidic torsion conformations. …”
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    A nucleobase-centered coarse-grained representation for structure prediction of RNA motifs
  8. 3428
    “…For at least 18–47% RS introns, we detected RS junction reads only after detecting canonical splicing junction reads, supporting the notion that these introns were removed by both recursive splicing and canonical splicing. …”
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    The temporal landscape of recursive splicing during Pol II transcription elongation in human cells
  9. 3429
    “…The eigenvalue statistics of the resulting grand canonical matrix models (of random size) corresponds exactly to the grand canonical measure of free fermions with classical boundary conditions.…”
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    Free Fermions and the Classical Compact Groups
  10. 3430
    “…This review will summarize literature available on the role of CAV1 in cancer, highlighting particularly our understanding of the canonical (CAV1 in the plasma membrane) and non-canonical pathways (CAV1 in organelles and exosomes) linked to the dual role of the protein as a tumor suppressor and promoter of metastasis. …”
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    Caveolin-1 function at the plasma membrane and in intracellular compartments in cancer
  11. 3431
    “…The human non-canonical inflammasome controls caspase-4 activation and gasdermin-D-dependent pyroptosis in response to cytosolic bacterial lipopolysaccharide (LPS). …”
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    Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria
  12. 3432
    “…WNT5B signals through the non-canonical β-catenin-independent signaling pathway and often functions as an antagonist of canonical WNT signaling. …”
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    WNT5B in Physiology and Disease
  13. 3433
    “…Thus, RCOR1 represses transcription in two ways—first, via a canonical mechanism by erasing transcriptionally permissive histone modifications through associating with HDACs and, second, via a non-canonical mechanism that deacetylates RNA POL-II’s CTD to inhibit productive elongation. …”
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    Unveiling RCOR1 as a rheostat at transcriptionally permissive chromatin
  14. 3434
    “…Previously, we have shown that the translocation of Grainyhead-like 3 (GRHL3) transcription factor from the nucleus to the cytoplasm triggers the switch from canonical Wnt signaling for epidermal differentiation to non-canonical Wnt signaling for epithelial morphogenesis. …”
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    USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components
  15. 3435
    “…While most isomiRs are functionally redundant compared to their canonical counterparts, the so-called 5’isomiRs exhibit a shifted 5’ end and therefore a shifted seed sequence resulting in a different target spectrum. …”
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    The highly expressed 5’isomiR of hsa-miR-140-3p contributes to the tumor-suppressive effects of miR-140 by reducing breast cancer proliferation and migration
  16. 3436
    por Hauer, M., Wheaton, S.
    Publicado 2009
    “…The system under consideration is sampled grand canonically in the Boltzmann approximation. A re-weighting scheme is then introduced to account for conservation of charges (baryon number, strangeness, electric charge) and energy and momentum, effectively allowing for extrapolation of grand canonical results to the microcanonical limit. …”
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    Statistical Ensembles With Finite Bath: A Description for an Event Generator
  17. 3437
    “…Early work on minimal models relied on detailed study of terminal and canonical singularities but many later results on log terminal singularities were obtained as consequences of the minimal model program. …”
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    Singularities of the minimal model program
  18. 3438
    por Tao, Renji
    Publicado 2009
    “…In addition, autonomous finite automata and Latin arrays, which are relative to the canonical form for one-key cryptosystems based on finite automata, are also discussed. …”
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    Finite automata and application to cryptography
  19. 3439
    “…We argue that GAP($\rho_\beta$) corresponds to the canonical ensemble.…”
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    On the Distribution of the Wave Function for Systems in Thermal Equilibrium
  20. 3440
    “…Using different cellular and molecular readouts, we generated a comprehensive picture of how ADAM17 and IR influence the EphA2 canonical and non-canonical pathway in NSCLC cells.…”
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    The role of EphA2 in ADAM17- and ionizing radiation-enhanced lung cancer cell migration
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