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3561“…The canonical nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway regulates central processes in mammalian cells and plays a fundamental role in the regulation of inflammation and immunity. …”
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3562“…DENR-MCT-1 heterodimer then participates in regulation of non-canonical translation initiation and ribosomal recycling. …”
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3563“…These findings suggested that PIISVYWK and FSVVPSPK promoted the canonical Wnt/β-catenin signaling pathway in osteogenesis of hBMMSCs. …”
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3564“…We study the implications of restricting the latter to four spacetime dimensions and give a direct link between its canonical form and the canonical form for the momentum amplituhedron. …”
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3565“…Excessive pyroptosis, however, leads to several inflammatory diseases, including sepsis and autoimmune disorders. Pyroptosis can be canonical or noncanonical. Upon microbe infection, the canonical pathway responds to pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), while the noncanonical pathway responds to intracellular lipopolysaccharides (LPS) of Gram-negative bacteria. …”
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3566por Zelli, Veronica, Compagnoni, Chiara, Capelli, Roberta, Corrente, Alessandra, Cornice, Jessica, Vecchiotti, Davide, Di Padova, Monica, Zazzeroni, Francesca, Alesse, Edoardo, Tessitore, Alessandra“…Initially ascribed to sequencing errors/artifacts, these isoforms, named isomiRs, are now considered non-canonical variants that originate from physiological processes affecting the canonical miRNA biogenesis. …”
Publicado 2021
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3567Progress toward SHAPE Constrained Computational Prediction of Tertiary Interactions in RNA Structurepor De Bisschop, Grégoire, Allouche, Delphine, Frezza, Elisa, Masquida, Benoît, Ponty, Yann, Will, Sebastian, Sargueil, Bruno“…Moreover, computationally, the problem is aggravated by the relevance of pseudoknots and non-canonical base pairs, which are hardly predicted efficiently. …”
Publicado 2021
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3568por Agarwal, Nitin K, Kim, Chae-Hwa, Kunkalla, Kranthi, Vaghefi, Amineh, Sanchez, Sandra, Manuel, Samantha, Bilbao, Daniel, Vega, Francisco, Landgraf, Ralf“…The oncoprotein Smoothened (SMO), a Frizzled-class-G-protein-coupled receptor, is the central transducer of Hedgehog (Hh) signaling. While canonical SMO signaling is best understood in the context of cilia, evidence suggests that SMO has other functions in cancer biology that are unrelated to canonical Hh signaling. …”
Publicado 2022
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3569por Mieszczanek, Juliusz, Strutt, Helen, Rutherford, Trevor J., Strutt, David, Bienz, Mariann, Gammons, Melissa V.“…Dishevelled is a cytoplasmic hub that transduces Wnt signals to cytoplasmic effectors, which can be broadly characterised as canonical (β-catenin dependent) and noncanonical, to specify cell fates and behaviours during development. …”
Publicado 2022
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3570“…NF-κB is the only signaling molecule that governs both pro- and anti-apoptotic, and pro- and anti-inflammatory responses. This is due to the canonical and non-canonical components of the NF-κB signaling pathway. …”
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3571“…Despite the fundamental role of canonical histones in nucleosome structure, there is no experimental system for higher eukaryotes in which basic questions about histone function can be directly addressed. …”
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3572“…This review will describe the canonical and newly identified functions of Dicer.…”
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3573“…We explore information flow in finite active matter flocks by simulating the canonical Vicsek model and estimating the flow of information as a function of noise (the variability in the extent to which each animal aligns with its neighbours). …”
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3574por Aguilar Troyano, Francisco José, Merkens, Kay, Anwar, Khadijah, Gómez‐Suárez, Adrián“…In this Minireview, we provide a broad overview of the advancements made in this field during the last decade, focusing on methods for the de novo synthesis of α‐, β‐, and γ‐AAs, as well as for the selective derivatisation of canonical and non‐canonical α‐AAs.…”
Publicado 2020
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3575por Brammer, Jan C., Blanke, Gerd, Kellner, Claudia, Hoffmann, Alexander, Herres-Pawlis, Sonja, Schatzschneider, Ulrich“…TUCAN is a canonical serialization format that is independent of domain-specific concepts of structure and bonding. …”
Publicado 2022
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3576por Maharana, Jnanadeva“…We introduce a set of generators of canonical transformations to exhibit the target space symmetries such as the general coordinate transformation and the gauge transformation of antisymmetric tensor field. …”
Publicado 1998
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3577por Ferrara, Sergio, Kallosh, Renata, Linde, Andrei, Marrani, Alessio, Van Proeyen, Antoine“…We find that the conditions for canonical kinetic terms are satisfied for the NMSSM scalars in the Jordan frame, which leads to a simple action. …”
Publicado 2010
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3578“…For a particular solution L_G^{ab}, the unified system reduces to the canonical stress tensors and conventional Einstein equations of the sigma model, and the system reduces to the general affine-Virasoro construction and the VME when the sigma model is taken to be the WZW action. …”
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3579por Wertman, Ronit Schwartz, Go, Christina K., Saller, Benedikt S., Groß, Olaf, Scott, Phillip, Brodsky, Igor E.“…Critically, activation of caspase-8 and activation of the canonical inflammasome are kinetically and spatially separable events, as rapid capase-8 activation occurs within multiple foci throughout the cell, followed by delayed subsequent assembly of a single canonical inflammasome. …”
Publicado 2023
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3580por Schwab, Kristopher R, Patterson, Larry T, Hartman, Heather A, Song, Ni, Lang, Richard A, Lin, Xinhua, Potter, S Steven“…BACKGROUND: The pygopus gene of Drosophila encodes an essential component of the Armadillo (β-catenin) transcription factor complex of canonical Wnt signaling. To better understand the functions of Pygopus-mediated canonical Wnt signaling in kidney development, targeted mutations were made in the two mammalian orthologs, Pygo1 and Pygo2. …”
Publicado 2007
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