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341
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342por Lomin, Sergey N, Myakushina, Yulia A, Kolachevskaya, Oksana O, Getman, Irina A, Arkhipov, Dmitry V, Savelieva, Ekaterina M, Osolodkin, Dmitry I, Romanov, Georgy AEnlace del recurso
Publicado 2018
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343“…Recent studies focusing on the localization and functions of Eg5 in plants have demonstrated that in addition to spindle organization, this motor protein has non‐canonical functions, such as chromosome segregation and cytokinesis, that have not been observed in animals. …”
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344“…Using a set of basic fitness landscapes, the so‐called canonical equation for the evolution of genetic instability on a minimal scenario associated with a population of unstable cells is derived. …”
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345por Liu, Yajun, Luo, Xia, Shan, Hao, Fu, Yuanyuan, Gu, Qianqian, Zheng, Xueping, Dai, Qi, Xia, Fan, Zheng, Zhihua, Liu, Peiqing, Yin, Xiao-Ming, Hong, Liang, Li, Min“…Moreover, mounting evidence has indicated that non-canonical LC3 lipidation (NCLL) may reflect NCA. We and others have reported that niclosamide (Nic), an anti-helminthic drug approved by the Food and Drug Administration, could induce canonical autophagy via a feedback downregulation of mTOR complex 1. …”
Publicado 2019
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346“…Here, we report that the glycosidic bond in canonical pyrimidine and purine ribonucleotides can be formed by direct coupling of cyclic carbohydrate phosphates with free nucleobases, all reported to be available by experimentally supported pathways that might have operated on early Earth.…”
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347por Saleh, Aya M., Wilding, Kristen M., Calve, Sarah, Bundy, Bradley C., Kinzer-Ursem, Tamara L.“…Metabolic labeling of proteins with non-canonical amino acids (ncAAs) provides unique bioorthogonal chemical groups during de novo synthesis by taking advantage of both endogenous and heterologous protein synthesis machineries. …”
Publicado 2019
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348“…This is evident in the high degree of instability displayed by N-glycosidic bonds of canonical purine ribonucleotides under the same geothermal conditions that otherwise readily favors polymerization. …”
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349por Inoue, Daichi, Chew, Guo-Liang, Liu, Bo, Michel, Brittany C., Pangallo, Joseph, D’Avino, Andrew R., Hitchman, Tyler, North, Khrystyna, Lee, Stanley Chun-Wei, Bitner, Lillian, Block, Ariele, Moore, Amanda R., Yoshimi, Akihide, Escobar-Hoyos, Luisa, Cho, Hana, Penson, Alex, Lu, Sydney X., Taylor, Justin, Chen, Yu, Kadoch, Cigall, Abdel-Wahab, Omar, Bradley, Robert K.“…We report that diverse SF3B1 mutations converge on repression of BRD9, a core component of the recently described GLTSCR1/1L-containing non-canonical BAF (ncBAF) chromatin remodeling complex(5–7). …”
Publicado 2019
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350“…We then explore Gregor Mendel’s story to demonstrate the culturally laden nature of the history of science as well as the nature of our current curricular canon. The article concludes with a postulated alternative method to genetics education in a general biology course that reflects the culturally laden nature of our genetics knowledge, as well as our current understanding of inheritance.…”
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351por Bello-Perez, Melissa, Sola, Isabel, Novoa, Beatriz, Klionsky, Daniel J., Falco, Alberto“…Thus, the combinatory treatment of COVID-19 with drugs affecting both canonical and noncanonical autophagy pathways may be a turning point in the fight against this and other viral infections, which may also imply beneficial prospects of long-term protection.…”
Publicado 2020
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352“…To overcome this challenge, we propose to apply non-canonical redox cofactors (NRCs) in metabolic networks: cofactors that channel electrons exclusively from substrate to product, forming orthogonal circuits for electron transfer.…”
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353“…In this case as well, we obtain that the recent canonical divergence is the quantum [Formula: see text]-divergence.…”
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354por Chen, Xingjuan, Sooch, Gagandeep, Demaree, Isaac S., White, Fletcher A., Obukhov, Alexander G.“…Twenty-five years ago, the first mammalian Transient Receptor Potential Canonical (TRPC) channel was cloned, opening the vast horizon of the TRPC field. …”
Publicado 2020
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355“…Later research discovered naturally occurring, active tRNAs that did not fit the established ‘canonical’ tRNA structure. This review discusses the non-canonical structures of some well-characterized natural tRNA species and describes how these structures relate to their role in translation. …”
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357por Liu, Fei, Li, Ji-Peng, Li, Lu-Shen, Liu, Qi, Li, Shan-Wei, Song, Ming-Lei, Li, Sha, Zhang, Yan“…We report here that the canonical α-SNAP in Arabidopsis is essential for male and female gametophytic development. …”
Publicado 2021
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358“…Here we study the details of the replication elongation process in the non-canonical RdRP of the Thosea asigna virus (TaV), an insect virus from the Permutatetraviridae family. …”
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359“…These non-canonical motifs occur independently of the TFs’ canonical motifs. …”
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