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  1. 3601
    por Huang, Ju, Brumell, John H.
    Publicado 2014
    “…In this Review, we discuss canonical and non-canonical autophagy pathways and our current knowledge of antibacterial autophagy, with a focus on the interplay between bacterial factors and autophagy components. …”
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    Bacteria–autophagy interplay: a battle for survival
  2. 3602
    “…As a downstream effector of adipocytokines and cytokines, its canonical and non-canonical activities affect mitochondrial functioning and cancer metabolism. …”
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    A STAT3 of Addiction: Adipose Tissue, Adipocytokine Signalling and STAT3 as Mediators of Metabolic Remodelling in the Tumour Microenvironment
  3. 3603
    “…In recent years, new bacterial ENR types were discovered, some of them with structures and mechanisms that differ from the canonical bacterial FabI enzymes. Here, we briefly review the diversity of structural and catalytic properties of the canonical FabI and the new FabK, FabV, FabL, and novel ENRs identified in a soil metagenome study. …”
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    Bacterial Enoyl-Reductases: The Ever-Growing List of Fabs, Their Mechanisms and Inhibition
  4. 3604
    por Klauder, John R.
    Publicado 2022
    “…Canonical quantization has created many valid quantizations that require infinite-line coordinate variables. …”
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    How to Secure Valid Quantizations
  5. 3605
    “…If this is true, then the origins of canonical microRNA biogenesis and microRNA-mediated gene regulation may postdate the last common metazoan ancestor. …”
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    MicroRNAs and essential components of the microRNA processing machinery are not encoded in the genome of the ctenophore Mnemiopsis leidyi
  6. 3606
    “…In this study, we demonstrate that FZDRs activate G proteins and trigger non-canonical Wnt signaling via the Dishevelled-binding protein, Daple. …”
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    Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling
  7. 3607
    “…Binding of both substrates, the canonical nucleosome and the H2A.Z-H2B dimer, is essential for activation of SWR1. …”
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    H2A histone-fold and DNA elements in nucleosome activate SWR1-mediated H2A.Z replacement in budding yeast
  8. 3608
    “…Depending on their mode of action, these SPIs can be categorized into serpins, canonical inhibitors and alpha-2-macroglobulins (A2Ms). …”
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    Identification and characterization of serine protease inhibitors in a parasitic wasp, Pteromalus puparum
  9. 3609
    “…We detected abundant expression of two transcrtiption factors mediating canonical Wnt signalling, Tcf7L1 and Tcf7L2, in the ventricular zone of the embryonic neocortex. …”
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    Tcf7L2 is essential for neurogenesis in the developing mouse neocortex
  10. 3610
    “…Therefore, miR-20b and canonical Wnt signaling were coupled through a feed-forward positive feedback loop, forming a biological regulatory circuit. …”
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    miR-20b promotes growth of non-small cell lung cancer through a positive feedback loop of the Wnt/β-catenin signaling pathway
  11. 3611
    “…We defined the novel classification of these motifs. It can handle both canonical and non-canonical cases. Based on this new taxonomy, we implemented a method that automatically recognizes the types of tetrads and quadruplexes occurring as unimolecular structures. …”
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    Topology-based classification of tetrads and quadruplex structures
  12. 3612
    “…Here, we report that ADAR1p110 regulates R-loop formation and genome stability at telomeres in cancer cells carrying non-canonical variants of telomeric repeats. ADAR1p110 edits the A-C mismatches within RNA:DNA hybrids formed between canonical and non-canonical variant repeats. …”
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    ADAR1 RNA editing enzyme regulates R-loop formation and genome stability at telomeres in cancer cells
  13. 3613
    “…This may be explained by miRNA specifically targeting the canonical isoform. Our study is the first one that shows the expression of both isoforms in colon tissues. …”
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    Colorectal cancer promoter methylation alteration affects the expression of glutamate ionotropic receptor AMPA type subunit 4 alternative isoforms potentially relevant in colon tissue
  14. 3614
    “…However, H3K27me3-independent non-canonical functions of EZH2 are incompletely understood. …”
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    EZH2 T367 phosphorylation activates p38 signaling through lysine methylation to promote breast cancer progression
  15. 3615
    “…In contrast, the samples of the three affected siblings contained two different glycopeptide peaks, corresponding to the canonical tetrasaccharide and to the non‐canonical trisaccharide linkage region modifications in individual ratios of 61/38, 73/27, and 59/41. …”
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    Glycosaminoglycan linkage region of urinary bikunin as a potentially useful biomarker for β3GalT6‐deficient spondylodysplastic Ehlers–Danlos syndrome
  16. 3616
    “…NASH and HCC depend on inflammatory signaling, whose master regulator is the NFκB transcription factor family, activated by canonical and non-canonical pathways. METHODS: Here, we investigated non-canonical NFκB-inducing kinase (NIK/MAP3K14) in metabolic NASH, NASH to HCC transition, and DEN-induced HCC. …”
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    NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition
  17. 3617
    “…We define 49 engineered mutually orthogonal pairs that recognize distinct non-canonical amino acids or alpha hydroxy acids and decode distinct codons. …”
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    Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles
  18. 3618
    por Fierz, Markus
    Publicado 2001
    “…Fierz gives a differential equation and the canonical description of its solution.…”
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    Pauli letter collection: letter to Wolfgang Pauli
  19. 3619
    por Brustein, Ram, Hadad, Merav
    Publicado 2012
    “…We show that the Wald Noether charge entropy is canonically conjugate to the opening angle at the horizon. …”
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    Wave function of the quantum black hole
  20. 3620
    “…Here, we demonstrate distinct roles for Notch4 signaling versus canonical Notch signaling in embryonic dermal lymphangiogenesis. …”
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    Unique functions for Notch4 in murine embryonic lymphangiogenesis
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