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Mostrando 501 - 520 Resultados de 23,561 Para Buscar '"canonization"', tiempo de consulta: 0.22s Limitar resultados
  1. 501
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    Editorial: Understanding the Importance of Non-Canonical tRNA Function
  2. 502
    por Schuller, Marion, Ahel, Ivan
    Publicado 2022
    “…Yet over the last years, there is increasing evidence of non-canonical forms of ADP-ribosylation that are catalysed by certain members of the ADP-ribosyltransferase family and go beyond traditional protein ADP-ribosylation signalling. …”
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    Beyond protein modification: the rise of non-canonical ADP-ribosylation
  3. 503
    “…The advance of experimental and computational techniques has allowed us to highlight the existence of numerous different mechanisms of RNA maturation, which have been so far unknown. Besides canonical splicing, consisting of the removal of introns from pre-mRNA molecules, non-canonical splicing events may occur to further increase the regulatory and coding potential of the human genome. …”
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    Non-Canonical Splicing and Its Implications in Brain Physiology and Cancer
  4. 504
    por Kaur, Sarabjeet, Sharma, Purshotam
    Publicado 2019
    “…The preRNA is proposed to contain non-canonical, heterocyclic bases that possess the above-mentioned capabilities. …”
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    Radical pathways for the formation of non-canonical nucleobases in prebiotic environments
  5. 505
    “…In this Review, we highlight such non-canonical targets in preclinical MS research with a focus on five highly promising areas: oligodendrocytes; the blood–brain barrier; metabolites and cellular metabolism; the coagulation system; and tolerance induction. …”
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    Thinking outside the box: non-canonical targets in multiple sclerosis
  6. 506
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    Manganese Utilization in Salmonella Pathogenesis: Beyond the Canonical Antioxidant Response
  7. 507
    “…Our results provide testable predictions that constrain the landscape of suitable biophysical models, while supporting noise-driven dynamics close to a bifurcation as a canonical mechanism underlying the complex fluctuations that characterize endogenous brain activity.…”
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    Data-driven discovery of canonical large-scale brain dynamics
  8. 508
    “…Activation of the canonical Wingless‐related integration site (Wnt) pathway has been shown to increase bone formation and therefore has therapeutic potential for use in orthopedic conditions. …”
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    Therapeutic approaches to activate the canonical Wnt pathway for bone regeneration
  9. 509
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    Thiol catalyzed formation of NO-ferroheme regulates canonical intravascular NO signaling
  10. 510
    por Yi, Yang, Li, Yanqiang, Chen, Kaifu, Cao, Qi
    Publicado 2023
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    Unveiling the non-canonical functions of EZH2 in prostate cancer
  11. 511
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    Homeostatic, Non-Canonical Role of Macrophage Elastase in Vascular Integrity
  12. 512
    “…In contrast, some of the Aβ oligomer effects were blocked by Ryanodine. We conclude that canonical Wnt/β-catenin signaling controls neuronal survival, and that non-canonical Wnt/Ca(2+)signaling modulates mitochondrial dysfunction. …”
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    Canonical Wnt signaling protects hippocampal neurons from Aβ oligomers: role of non-canonical Wnt-5a/Ca(2+) in mitochondrial dynamics
  13. 513
    “…This means compound 19 dually inhibits canonical and non-canonical functions of telomerase. …”
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    A novel curcumin analog inhibits canonical and non-canonical functions of telomerase through STAT3 and NF-κB inactivation in colorectal cancer cells
  14. 514
    “…EGCG down-regulated the canonical pathways in MDSCs, mainly through the Arg-1/iNOS/Nox2/NF-κB/STAT3 signaling pathway. …”
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    Green Tea Polyphenol EGCG Attenuates MDSCs-mediated Immunosuppression through Canonical and Non-Canonical Pathways in a 4T1 Murine Breast Cancer Model
  15. 515
    “…In summary this study shows that simultaneous activation of the AhR and NF-κB signaling pathways leads to synergistic and prolonged induction of IL-22 by integrating signals of the canonical and non-canonical AhR pathway.…”
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    Aryl Hydrocarbon Receptor Signaling Synergizes with TLR/NF-κB-Signaling for Induction of IL-22 Through Canonical and Non-Canonical AhR Pathways
  16. 516
    “…Here, we performed a critical evaluation of the role of antipsychotics in synaptic plasticity, focusing on their canonical and non-canonical mechanisms of action relevant to the treatment of schizophrenia and their subsequent implication for the pathophysiology and potential therapy of TRS.…”
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    Canonical and Non-Canonical Antipsychotics’ Dopamine-Related Mechanisms of Present and Next Generation Molecules: A Systematic Review on Translational Highlights for Treatment Response and Treatment-Resistant Schizophrenia
  17. 517
    “…Here we demonstrate that Vpu can inhibit both canonical and non-canonical NF-κB pathways, through the direct inhibition of the F-box protein β-TrCP, the substrate recognition portion of the Skp1-Cul1-F-box (SCF)(β-TrCP) ubiquitin ligase complex. …”
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    Differential dysregulation of β-TrCP1 and -2 by HIV-1 Vpu leads to inhibition of canonical and non-canonical NF-κB pathways in infected cells
  18. 518
    “…Aortic root aneurysm formation is a cardinal feature of Marfan syndrome (MFS) and likely TGF‐β driven via Smad (canonical) and ERK (non‐canonical) signalling. The current study assesses human MFS vascular smooth muscle cell (SMC) phenotype, focusing on individual contributions by Smad and ERK, with Notch3 signalling identified as a novel compensatory mechanism against TGF‐β‐driven pathology. …”
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    Divergent effects of canonical and non‐canonical TGF‐β signalling on mixed contractile‐synthetic smooth muscle cell phenotype in human Marfan syndrome aortic root aneurysms
  19. 519
    por Miceli Méndez, Clara Luz
    Publicado 2009
    Libro
    Orquídeas y bromelias del parque nacional Cañón del Sumidero
  20. 520
    Libro
    Six sonatas in Canon, opus 5 for 2 flutes or 2 violinsn
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