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Mostrando 661 - 680 Resultados de 23,561 Para Buscar '"canonization"', tiempo de consulta: 0.29s Limitar resultados
  1. 661
    “…PURPOSE: The purpose of this study was to evaluate the role of the canonical Wnt signaling in the development of the myopia. …”
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    Canonical Wnt Signaling Drives Myopia Development and Can Be Pharmacologically Modulated
  2. 662
    “…Here, we review the influence of non-canonical nucleic acid structures in disease-related genes on disease onset and progression.…”
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    Roles of non-canonical structures of nucleic acids in cancer and neurodegenerative diseases
  3. 663
    “…Also, alcohol is a physiological ER stress inducer, and the link between alcoholism and progression of prostate cancer (PCa) is well documented but not well characterized. According to the canonical model, the mediator of ER stress, ATF6, is cleaved sequentially in the Golgi by S1P and S2P proteases; thereafter, the genes responsible for unfolded protein response (UPR) undergo transactivation. …”
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    The non-canonical mechanism of ER stress-mediated progression of prostate cancer
  4. 664
    “…This paper presents the implementation of nonlinear canonical correlation analysis (NLCCA) approach to detect steady-state visual evoked potentials (SSVEP) quickly. …”
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    Solving the SSVEP Paradigm Using the Nonlinear Canonical Correlation Analysis Approach
  5. 665
    por Shibata, Atsushi, Jeggo, Penny A
    Publicado 2020
    “…The significance of canonical DNA non-homologous end-joining (c-NHEJ) for DNA double strand break (DSB) repair has increased from lower organisms to higher eukaryotes, and plays the predominant role in human cells. …”
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    Canonical DNA non-homologous end-joining; capacity versus fidelity
  6. 666
    “…However, in recent years, several non-canonical protein substrates of NEDD8 have been identified. …”
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    The Many Potential Fates of Non-Canonical Protein Substrates Subject to NEDDylation
  7. 667
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    Desmosomes: emerging pathways and non-canonical functions in cardiac arrhythmias and disease
  8. 668
    “…Here, we report the identification of a novel family of transcriptional repressors in the Bacteroidetes that orchestrate a canonical response to DNA damage in this phylum. These proteins belong to the S24 peptidase family, but are structurally different from LexA. …”
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    Non-canonical LexA proteins regulate the SOS response in the Bacteroidetes
  9. 669
    “…In plants, there are two types of Gα subunits: canonical Gα subunits structurally similar to their animal counterparts and unconventional extra-large Gα subunits (XLGs) containing a C-terminal domain homologous to the canonical Gα along with an extended N-terminal domain. …”
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    Heterotrimeric G Proteins in Plants: Canonical and Atypical Gα Subunits
  10. 670
    “…A class of unstable products emerge from non-canonical translation and processing of unannotated mammalian and viral ORFs and their peptides are cryptic in nature. …”
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    The Hidden Enemy Within: Non-canonical Peptides in Virus-Induced Autoimmunity
  11. 671
    por Zhang, Jun, Wong, Ting-Kam Leonard
    Publicado 2022
    “…This paper systematically presents the [Formula: see text]-deformation as the canonical framework of deformation to the dually flat (Hessian) geometry, which has been well established in information geometry. …”
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    λ-Deformation: A Canonical Framework for Statistical Manifolds of Constant Curvature
  12. 672
    “…Canonical Wnt/β-catenin signaling is a complex cell-communication mechanism that has a central role in the progression of various cancers. …”
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    The interaction of canonical Wnt/β-catenin signaling with protein lysine acetylation
  13. 673
    “…Non-canonical amino acids (ncAAs) have been utilized as an invaluable tool for modulating the active site of the enzymes, probing the complex enzyme mechanisms, improving catalytic activity, and designing new to nature enzymes. …”
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    Non-Canonical Amino Acid-Based Engineering of (R)-Amine Transaminase
  14. 674
    “…Required parameters for this canonical holistic morphometric analysis (cHMA) method were identified and the robustness of the method was evaluated. …”
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    A computational framework for canonical holistic morphometric analysis of trabecular bone
  15. 675
    por Nhieu, Jennifer, Lin, Yu-Lung, Wei, Li-Na
    Publicado 2022
    “…In this review, we discuss the emerging role of Cellular Retinoic Acid Binding Protein 1 (CRABP1) as a mediator of non-canonical activities of retinoic acid (RA) and relevance to human diseases. …”
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    CRABP1 in Non-Canonical Activities of Retinoic Acid in Health and Diseases
  16. 676
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    Aurintricarboxylic acid is a canonical disruptor of the TAZ-TEAD transcriptional complex
  17. 677
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    Context-Dependent Regulation of Gene Expression by Non-Canonical Small RNAs
  18. 678
    “…WNT signalling includes the β-catenin canonical pathway and the non-canonical pathways, namely the planar cell polarity and the calcium-dependent pathways. …”
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    Non-canonical WNT signalling in cardiovascular disease: mechanisms and therapeutic implications
  19. 679
    “…We find that elevations in cerebrospinal fluid copper, manganese and zinc levels are altered early in disease prior to alterations in canonical biomarkers of HD although these changes are not present in plasma. …”
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    Alterations in metal homeostasis occur prior to canonical markers in Huntington disease
  20. 680
    “…Wnt signaling is essential during animal development and regeneration, but also plays an important role in diseases such as cancer and diabetes. The canonical Wnt signaling pathway is one of the most conserved signaling cascades in the animal kingdom, with the T‐cell factor/lymphoid enhancer factor (TCF/LEF) proteins being the major mediators of Wnt/β‐catenin‐regulated gene expression. …”
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    Evolutionary diversification of the canonical Wnt signaling effector TCF/LEF in chordates
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