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741“…We used Wold's method for calculation of the canonical variates, and we applied ridge penalization to the regression of pathway genes on canonical variates of the non-pathway genes, and the elastic net to the regression of non-pathway genes on the canonical variates of the pathway genes. …”
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742
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743por Cocquyt, Ellen, Gile, Gillian H, Leliaert, Frederik, Verbruggen, Heroen, Keeling, Patrick J, De Clerck, Olivier“…CONCLUSIONS: We compare different evolutionary scenarios for the complex phylogenetic distribution of this non-canonical genetic code. A single transition to the non-canonical code followed by a reversal to the canonical code in the Bryopsidales is highly improbable due to the profound genetic changes that coincide with codon reassignment. …”
Publicado 2010
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744por Aisagbonhi, Omonigho, Rai, Meena, Ryzhov, Sergey, Atria, Nick, Feoktistov, Igor, Hatzopoulos, Antonis K.“…Coincidently with canonical Wnt activation, endothelial-to-mesenchymal transition (EndMT) was also triggered after MI. …”
Publicado 2011
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745por Dazard, Jean-Eudes, Zhang, Keman, Sha, Jingfeng, Yasin, Omar, Cai, Linda, Nguyen, Chien, Ghosh, Mrinal, Bongorno, Jennifer, Harter, Marian L“…Approximately 2,401 genes were significantly modulated by E1A, and of these, 385 and 1033 met the criteria for generating networks and functional and canonical pathway analysis respectively, as determined by using Ingenuity Pathway Analysis software. …”
Publicado 2011
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746por Orioli, Andrea, Pascali, Chiara, Quartararo, Jade, Diebel, Kevin W., Praz, Viviane, Romascano, David, Percudani, Riccardo, van Dyk, Linda F., Hernandez, Nouria, Teichmann, Martin, Dieci, Giorgio“…A panel of such non-canonical signals was found to direct transcription termination of unusual Pol III-synthesized viral pre-miRNA transcripts in gammaherpesvirus 68-infected cells. …”
Publicado 2011
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747por Varecza, Zoltan, Kvell, Krisztian, Talabér, Gergely, Miskei, Gyorgy, Csongei, Veronika, Bartis, Domokos, Anderson, Graham, Jenkinson, Eric J., Pongracz, Judit E.Enlace del recurso
Publicado 2011
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748“…These results implicate TEM8 expression in endothelial cells in regulating the canonical Wnt signaling pathway at this day of CAM development. …”
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749por Hamid, Jemila S, Meaney, Christopher, Crowcroft, Natasha S, Granerod, Julia, Beyene, Joseph“…However, the first canonical variate from CCA revealed strong multivariate correlation (ρ = 0.71, se = 0.03, p = 0.013) between the two sets. …”
Publicado 2011
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750“…Few researchers have looked into the different medical issues in his best known work, the Canon of Medicine, particularly with regard to ophthalmology. …”
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751
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752“…In situ hybridization showed that the canonical WNT ligands and receptors were predominantly located in the peripheral epithelium, whereas the canonical WNT signal transducers and transcription factors were not only detected in the respiratory epithelium, but some were also scattered at low levels in the surrounding mesenchyme in the developing human lung. …”
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753por Yuan, Zhongshang, Gao, Qingsong, He, Yungang, Zhang, Xiaoshuai, Li, Fangyu, Zhao, Jinghua, Xue, Fuzhong“…Earlier we proposed a statistic based on canonical correlations (CCU) as a gene-based method for detecting gene-gene co-association. …”
Publicado 2012
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754por Gill, Jason J, Berry, Joel D, Russell, William K, Lessor, Lauren, Escobar-Garcia, Diego A, Hernandez, Daniel, Kane, Ashley, Keene, Jennifer, Maddox, Matthew, Martin, Rebecca, Mohan, Sheba, Thorn, Ashlyn M, Russell, David H, Young, RyEnlace del recurso
Publicado 2012
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755“…Investigation of the diversity, biological consequences, and mechanisms of the canonical and noncanonical alternative splicing events will help one to identify those transcripts which are promising for using in genetic engineering and selection of stress-tolerant plants.…”
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756por Nicastro, Giuseppe, García-Mayoral, María Flor, Hollingworth, David, Kelly, Geoff, Martin, Stephen R., Briata, Paola, Gherzi, Roberto, Ramos, Andres“…The structure of the KH3-RNA complex explains the protein recognition of this non-canonical KH target sequence and we demonstrate that the specificity of this binding is crucial for the functional interaction between the protein and the miRNA precursor.…”
Publicado 2012
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757“…In addition, NEDD4L, but not catalytically inactive NEDD4L, inhibited canonical WNT signaling at or below the level of β-catenin in vitro. …”
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758por ZHOU, SHI-YONG, XU, MEI-LIN, WANG, SHAO-QING, ZHANG, FANG, WANG, LEI, WANG, HUA-QING“…It is necessary to improve the understanding of the molecular mechanisms involved in lung cancer in order to develop more effective therapeutics for the treatment of this fatal disease. The canonical Wnt signaling pathway has been known to be important in a number of cancer types, including lung cancer. …”
Publicado 2014
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759
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760por Sondo, Elvira, Scudieri, Paolo, Tomati, Valeria, Caci, Emanuela, Mazzone, Amelia, Farrugia, Gianrico, Ravazzolo, Roberto, Galietta, Luis J.V.“…We hypothesized that, in the mutant M1X, translation may start at a position before the second ATG, using a non-canonical start codon. Therefore, we placed an HA-epitope at position 89 in the M1X mutant. …”
Publicado 2014
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