Mostrando 781 - 800 Resultados de 23,561 Para Buscar '"canonization"', tiempo de consulta: 0.20s Limitar resultados
  1. 781
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  3. 783
    “…It has been shown that the same canonical cortical circuit model with mutual inhibition and a fatigue process can explain perceptual rivalry and other neurophysiological responses to a range of static stimuli. …”
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  4. 784
    “…By using a combination of various bioinformatics analyses (e.g. domain architecture, cellular localization) and exhaustive literature and database searches (e.g. expression profiles, protein interactors), we classified FAM46 proteins as active non-canonical poly(A) polymerases, which modify cytosolic and/or nuclear RNA 3′ ends. …”
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  5. 785
    por Cheung, Lydia WT, Mills, Gordon B
    Publicado 2015
    “…We recently reported neomorphic p85α mutants that induce signaling cascades not predicted by the canonical functions of p85α, suggesting the need to functionally annotate specific mutations in cancer genes for effective genome-informed personalized therapy.…”
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  6. 786
    “…Silencing by a specific siRNA of NIK, the upstream kinase of the non-canonical NFκB pathway, prevented CCL21 upregulation but did not modulate CCL19 or RANTES expression in response to TWEAK, thus establishing CCL21 as a non-canonical NFκB target in podocytes. …”
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  7. 787
    “…These data suggest that the physiological effects of these plant polysaccharides are not due to inhibition of the canonical galectin carbohydrate-binding site.…”
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  8. 788
    “…In contrast, the non-canonical Wnt pathways are less well characterized, and few if any possible drug targets exist to tackle cancers caused by dysregulation of these Wnt offshoots. …”
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  9. 789
    “…We find that our length-independent method not only clusters a larger number of CDRs, but also predicts canonical class from sequence better than the standard length-dependent approach. …”
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  10. 790
  11. 791
    “…There are several types of these ion channels, but here we address those formed by assembly of transient receptor potential canonical (TRPC) proteins, particularly those which involve two closely related members of the family: TRPC4 and TRPC5. …”
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  12. 792
  13. 793
    “…Here we use human embryonic stem cells (hESCs) to analyze systematically in human cardiomyocyte development the expression of endogenous Wnt signaling components, monitor pathway activity, and dissect stage-specific requirements for canonical and noncanonical Wnt signaling mechanisms using small-molecule inhibitors. …”
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  14. 794
  15. 795
    por Seligmann, Hervé
    Publicado 2016
    “…Unbiased analyses couldn't reconstruct experimental tryptic digestion if most detected non-canonical peptides were false positives. Detected non-tryptic non-canonical peptides map preferentially on corresponding, previously described non-canonical transcripts, as for tryptic non-canonical peptides. …”
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  16. 796
    “…In this article we introduce Pyrcca, an open-source Python package for performing canonical correlation analysis (CCA). CCA is a multivariate analysis method for identifying relationships between sets of variables. …”
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  17. 797
    “…The dataset presented here represents analysis supplied by the local proteomics core facility on samples submitted to it in support of the article “Assembly of proteasome subunits into non-canonical complexes in vivo” Hammack and Kusmierczyk (2016) [1]. …”
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  18. 798
    por Olivos, David J., Mayo, Lindsey D.
    Publicado 2016
    “…In this review, we will highlight the emerging non-canonical functions and regulation of p53 in stem cells. …”
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  19. 799
    “…Increased osteoarthritis in WNT16-deficient mice was associated with excessive activation of canonical WNT signalling. In vitro, high doses of WNT16 weakly activated canonical WNT signalling, but, in co-stimulation experiments, WNT16 reduced the capacity of WNT3a to activate the canonical WNT pathway. …”
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