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  1. 1041
    “…Thus, arginine methylation provides the canonical Wnt pathway with metabolic sensing properties through SAM. …”
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    Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation
  2. 1042
    “…However, in the IMCD cells of hypokalemic Atg7(Δpc) mice, these canonical autophagic vacuoles were markedly reduced, whereas numerous small regular shaped LC3-negative/RAB9-positive non-canonical autophagic vacuoles were observed along with diffusely distributed total- and pS261-AQP2 in the cytoplasm. …”
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    Atg7-dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia
  3. 1043
    “…Here, we studied the ability of chlamydial LPS to activate the proinflammatory canonical and noncanonical inflammasome pathways in mouse bone marrow-derived macrophages (BMDM). …”
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    Chlamydia trachomatis Lipopolysaccharide Evades the Canonical and Noncanonical Inflammatory Pathways To Subvert Innate Immunity
  4. 1044
    “…Using reversible tethering of PcG proteins to ectopic sites in mouse embryonic stem cells, here we show that PRC1 can trigger transcriptional repression and Polycomb-dependent chromatin modifications. We find that canonical PRC1 (cPRC1), but not variant PRC1, maintains gene silencing through cell division upon reversal of tethering. …”
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    Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing
  5. 1045
    “…In this study, we establish minimal canonical microcircuit models as elements of hierarchical processing networks. …”
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    Emergence of cognitive priming and structure building from the hierarchical interaction of canonical microcircuit models
  6. 1046
    “…Our data highlight the potential of non-canonical translation initiation in expanding the capacity of the mitochondrial proteome and possibly also other cellular features.…”
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    Non-canonical translation initiation in yeast generates a cryptic pool of mitochondrial proteins
  7. 1047
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    Dissecting the sharp response of a canonical developmental enhancer reveals multiple sources of cooperativity
  8. 1048
    “…We therefore applied non‐canonical amino acid labelling to visualise and identify newly synthesised proteins in the K369I tau transgenic K3 mouse model of FTD. …”
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    Decreased synthesis of ribosomal proteins in tauopathy revealed by non‐canonical amino acid labelling
  9. 1049
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    Curcumin: a therapeutic strategy in cancers by inhibiting the canonical WNT/β-catenin pathway
  10. 1050
    “…The distribution of canonical and putative cannabinoid receptors in the peripheral and central nervous system of dogs is still in its infancy. …”
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    Cellular Distribution of Canonical and Putative Cannabinoid Receptors in Canine Cervical Dorsal Root Ganglia
  11. 1051
    “…In addition to poly(A)-tail dependent translation (PAT), early embryos perform poly(A)-tail independent non-canonical translation (PAINT) via deadenylated 3′UTRs. …”
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    Non-canonical translation via deadenylated 3′UTRs maintains primordial germ cells
  12. 1052
    “…Remarkably, under basal conditions, and having accounted for false site localisation probabilities, the number of unique non‐canonical phosphosites is approximately one‐third of the number of observed canonical phosphosites. …”
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    Strong anion exchange‐mediated phosphoproteomics reveals extensive human non‐canonical phosphorylation
  13. 1053
    “…Circular RNAs (circRNA) are a unique class of transcripts that can only be identified from sequence alignments spanning discordant junctions, commonly referred to as backsplice junctions (BSJ). Canonical splicing is also linked with circRNA biogenesis either from the parental transcript or internal to the circRNA, and is not fully utilized in circRNA software. …”
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    Ularcirc: visualization and enhanced analysis of circular RNAs via back and canonical forward splicing
  14. 1054
    “…We report the first Ru(ii) coordination compounds that interact with DNA through a canonical minor groove insertion mode and with selectivity for A/T rich sites. …”
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    Canonical DNA minor groove insertion of bisbenzamidine–Ru(ii) complexes with chiral selectivity
  15. 1055
    “…Five of six antibody CDR loops presumably adopt a so-called canonical structure out of a limited number of conformations. …”
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    Transitions of CDR-L3 Loop Canonical Cluster Conformations on the Micro-to-Millisecond Timescale
  16. 1056
    “…Its heterodimeric composition and homology to SWEET and semiSWEET transporters set the MPC apart from the canonical mitochondrial carrier family (named MCF or SLC25). …”
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    The mitochondrial carrier pathway transports non-canonical substrates with an odd number of transmembrane segments
  17. 1057
    por Frey, Katharina, Pucker, Boas
    Publicado 2020
    “…GC-AG and AT-AC are two major non-canonical splice site combinations, which have been known for years. …”
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    Animal, Fungi, and Plant Genome Sequences Harbor Different Non-Canonical Splice Sites
  18. 1058
    “…Descriptive analyses, t-tests, analysis of variance, Pearson’s correlation, and canonical correlation were used. The behavioral-psychological variable set was related to the predictor set for CAD prognosis, with a significant canonical variate of 0.67 (45% overlapping variance). …”
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    Canonical Correlation between Behavioral-Psychological Variables and Predictors of Coronary Artery Disease Prognosis
  19. 1059
    “…The present study provides the first proof-of-concept that fat-specific cold mimetics via activating non-canonical thermogenesis protect against obesity.…”
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    Wireless optogenetics protects against obesity via stimulation of non-canonical fat thermogenesis
  20. 1060
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    Molecular Dynamics Simulations Reveal Canonical Conformations in Different pMHC/TCR Interactions
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