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1161por Ding, Yu, Xi, Ying, Chen, Ting, Wang, Ji-yong, Tao, Dong-lei, Wu, Zhi-Li, Li, Yi-ping, Li, Chen, Zeng, Rong, Li, Lin“…Therefore, Caprin-2 promotes activation of the canonical Wnt signaling pathway by regulating LRP5/6 phosphorylation.…”
Publicado 2008
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1162Identification of cell cycle-related regulatory motifs using a kernel canonical correlation analysis“…RESULTS: We developed a framework that can detect correlations between gene expression profiles and the upstream sequences on the basis of the kernel canonical correlation analysis (kernel CCA). Using a yeast cell cycle dataset, we demonstrated that upstream sequence patterns were closely related to gene expression profiles based on the canonical correlation scores obtained by measuring the correlation between them. …”
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1163por Matluk, Nicholas, Rochira, Jennifer A, Karaczyn, Aldona, Adams, Tamara, Verdi, Joseph M“…CONCLUSION: Modulation of NRAGE expression revealed novel roles in regulating NF-κB activity in the non-canonical bone morphogenic protein signaling pathway. …”
Publicado 2010
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1164
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1165Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites“…Importantly, the method identifies a significant number of experimentally determined non-canonical and non-conserved sites.…”
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1166por Nalesso, Giovanna, Sherwood, Joanna, Bertrand, Jessica, Pap, Thomas, Ramachandran, Manoj, De Bari, Cosimo, Pitzalis, Costantino, Dell'Accio, Francesco“…WNT-3A activates both the β-catenin–dependent canonical pathway and the Ca(2+)/CaMKII noncanonical pathways, with distinct transcriptional targets. …”
Publicado 2011
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1167
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1168Reconstitution of a functional IS608 single-strand transpososome: role of non-canonical base pairingpor He, Susu, Hickman, Alison B., Dyda, Fred, Johnson, Neil P., Chandler, Michael, Ton-Hoang, Bao“…The cleavage sites, C, are not recognized directly by the protein but by short sequences 5′ to the foot of each IP, guide (G) sequences, using a network of canonical (‘Watson–Crick’) base interactions. In addition a set of non-canonical base interactions similar to those found in RNA structures are also involved. …”
Publicado 2011
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1169“…Local canonical correlation analysis (CCA) is a multivariate method that has been proposed to more accurately determine activation patterns in fMRI data. …”
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1170“…Additionally, Slm1-PH may have retained an active canonical site. We propose that the presence of both a canonical and a non-canonical binding pocket in Slm1-PH may account for the cooperative binding to PtdInsPs and DHS-1P.…”
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1172“…We show that HMGB1 alters the structure and stability of the canonical nucleosome (N) in a nonenzymatic, ATP-independent manner. …”
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1173por Stoltzfus, Jonathan D., Minot, Samuel, Berriman, Matthew, Nolan, Thomas J., Lok, James B.Enlace del recurso
Publicado 2012
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1174por Wang, Le, Pawlak, Erica A., Johnson, Philip J., Belknap, James K., Eades, Susan, Stack, Sharon, Cousin, Helene, Black, Samuel J.“…Versican gene expression is purportedly under control of the canonical Wnt signaling pathway and is a trigger for mesenchymal-to-epithelial transition; thus, its repression in laminar epithelial cells of laminitic horses may be associated with suppression of the canonical Wnt signaling pathway and loss of the epithelial cell phenotype. …”
Publicado 2013
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1176por Moslehi, Roxana, Mills, James L., Signore, Caroline, Kumar, Anil, Ambroggio, Xavier, Dzutsev, Amiran“…We propose that dysregulation of these canonical cancer molecular pathways occurs in preeclampsia and delineate the relevance of TFIIH, providing etiologic clues which could eventually translate into a therapeutic approach.…”
Publicado 2013
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1177“…The non-canonical NF-κB pathway is crucial for the immune system. …”
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1178“…Plexin signaling depends on their cytoplasmic GTPase activating protein (GAP) domain, which specifically inactivates the Ras homolog Rap through an ill-defined non-canonical catalytic mechanism. The plexin GAP is activated by semaphorin-induced dimerization, the structural basis for which remained unknown. …”
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1180por Chen, Xiaoping, Yang, Dachun, Ma, Shuangtao, He, Hongbo, Luo, Zhidan, Feng, Xiaoli, Cao, Tingbing, Ma, Liqun, Yan, Zhencheng, Liu, Daoyan, Tepel, Martin, Zhu, Zhiming“…Since increased calcium influx into vascular smooth muscle cells from spontaneously hypertensive rats (SHR) has been associated with variances of transient receptor potential canonical (TRPC) channels, in the present study we tested the hypothesis that increased vasomotion in hypertension is directly linked to increased TRPC expression. …”
Publicado 2010
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