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  1. 1201
    “…We observed that high glucose culture condition (HG) specifically activates canonical Wnt signaling in HCC cells, which is mediated by suppression of DKK4 (a Wnt antagonist) expression and enhanced β-catenin level. …”
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    Glucose induced activation of canonical Wnt signaling pathway in hepatocellular carcinoma is regulated by DKK4
  2. 1202
    “…This is the first time that aequorin variants incorporating non-canonical amino acids have shown to be active in vivo and useful as reporters in bioluminescence imaging.…”
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    Red-Shifted Aequorin Variants Incorporating Non-Canonical Amino Acids: Applications in In Vivo Imaging
  3. 1203
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    Proteome-wide measurement of non-canonical bacterial mistranslation by quantitative mass spectrometry of protein modifications
  4. 1204
    “…MATERIAL/METHODS: Rat pulmonary arteries and primary pulmonary arterial smooth muscle cells (PASMCs) were cultured in vitro and treated with lipopolysaccharide (LPS) and blockers of transient receptor potential canonical (TRPC) channels. Neointimal growth and arterial stenosis were observed on cryosections of cultured pulmonary arteries. …”
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    Upregulation of Transient Receptor Potential Canonical Channels Contributes to Endotoxin-Induced Pulmonary Arterial Stenosis
  5. 1205
    “…Activation of the canonical Wnt signaling pathway is an attractive anabolic therapeutic strategy for bone. …”
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    Transient Canonical Wnt Stimulation Enriches Human Bone Marrow Mononuclear Cell Isolates for Osteoprogenitors
  6. 1206
    “…Further research will reveal the full extent of both the canonical and non-canonical functions of Ca(V) channels in cancer and whether calcium channel blockers are beneficial in cancer treatment.…”
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    Ca(V) channels and cancer: canonical functions indicate benefits of repurposed drugs as cancer therapeutics
  7. 1207
    “…Activation of Wnt signaling or inhibition of both glycogen synthase kinase-3beta and Dickkopf 1, two key negative regulators of the canonical Wnt pathway, are able to protect against Abeta neurotoxicity and to ameliorate cognitive performance in AD patients. …”
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    Alzheimer Disease: Crosstalk between the Canonical Wnt/Beta-Catenin Pathway and PPARs Alpha and Gamma
  8. 1208
    “…Here we show that EZH2, through a methyltransferase-independent mechanism, promotes the transcriptional activation of the non-canonical NF-κB subunit RelB to drive self-renewal and the TIC phenotype of triple-negative breast cancer cells.…”
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    Non-Canonical EZH2 Transcriptionally Activates RelB in Triple Negative Breast Cancer
  9. 1209
    “…We find that non-canonical HR termination can occur in the absence of the classical non-homologous end joining gene XRCC4. …”
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    Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells
  10. 1210
    “…Here, we demonstrate experimentally that the T. cruzi RPA complex interacts with DNA via RPA-1 and is directly related to canonical functions, such as DNA replication and DNA damage response. …”
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    Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi
  11. 1211
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    Reconstituting regulation of the canonical Wnt pathway by engineering a minimal β-catenin destruction machine
  12. 1212
    “…In artery specific plaque analysis 50.4% of canonical pathways and 41.2% GO terms differentially expressed were in common for all three arterial beds. …”
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    Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques – Tampere Vascular Study
  13. 1213
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    Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche
  14. 1214
    “…In this study we evaluated the role of canonical Wnt signaling in the regulation of T cell function in a mouse colorectal cancer model. …”
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    Colorectal cancer cells suppress CD4+ T cells immunity through canonical Wnt signaling
  15. 1215
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    Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
  16. 1216
    “…Moreover, prostaglandin E2 by activating the canonical WNT pathway plays also a role in cancer. …”
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    Thermodynamics in cancers: opposing interactions between PPAR gamma and the canonical WNT/beta-catenin pathway
  17. 1217
    “…To further validate the role of canonical elements in super-enhancer formation, we investigated some additional signal-dependent transcription factors, confirming that certain, distinguished binding elements have a general organizer function. …”
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    Inducible super-enhancers are organized based on canonical signal-specific transcription factor binding elements
  18. 1218
    “…However, the molecular diversity of biologically active terpenoids is substantially increased by fully unrelated, non-canonical terpenoid cyclases. Their evolutionary origin has remained enigmatic. …”
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    Cryptic indole hydroxylation by a non-canonical terpenoid cyclase parallels bacterial xenobiotic detoxification
  19. 1219
    “…This work underscores the structural polymorphisms originated from a single highly G-rich sequence and demonstrates the existence of non-canonical G4s in cells, thus broadening the definition of G4-forming sequences. …”
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    Non-Canonical G-quadruplexes cause the hCEB1 minisatellite instability in Saccharomyces cerevisiae
  20. 1220
    “…The local initiation of non‐canonical WNT signaling shifts the accumulating myeloid cells toward a pro‐inflammatory state and impacts healing after myocardial infarction.…”
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    The cardiac microenvironment uses non‐canonical WNT signaling to activate monocytes after myocardial infarction
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