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  1. 1401
    “…Downstream targets of canonical Wnt signaling are cyclin D1 and c-myc. However both target genes are suppressed during differentiation of mouse myoblast cells, C2C12. …”
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    Canonical Wnt signaling is involved in switching from cell proliferation to myogenic differentiation of mouse myoblast cells
  2. 1402
    por Houseley, Jonathan, Tollervey, David
    Publicado 2011
    “…Our data suggest that a novel mode of break-induced replication occurs in repetitive DNA that is dependent on high homology but does not require the canonical homologous recombination machinery.…”
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    Repeat expansion in the budding yeast ribosomal DNA can occur independently of the canonical homologous recombination machinery
  3. 1403
    “…Finally, the concept of simultaneously inducing canonical Wnt activity and suppressing AKT signaling was translated into a combination of diet-derived agents. …”
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    A Switch from Canonical to Noncanonical Wnt Signaling Mediates Drug Resistance in Colon Cancer Cells
  4. 1404
    “…Here, we have discovered that SP1 binds also to a non-canonical DNA structure, a G-quadruplex, with high affinity. …”
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    A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro
  5. 1405
    “…Here we examined the effects of possessivity [sentences with or without a possessor] and canonicity [canonical or noncanonical word orders] using Japanese ditransitive sentences. …”
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    Left Inferior Frontal Activations Depending on the Canonicity Determined by the Argument Structures of Ditransitive Sentences: An MEG Study
  6. 1406
    “…Therefore, we sought to radiolabel the PTCH-1 ligand sonic (SHH) for detection of cancer cells with canonical HH activity. Receptor binding of (131)I-SHH was increased in cell lines with high HH pathway activation. …”
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    Detection of Canonical Hedgehog Signaling in Breast Cancer by 131-Iodine-Labeled Derivatives of the Sonic Hedgehog Protein
  7. 1407
    “…We examined the functional role of RNF11 with respect to canonical NF-κB signaling in neurons to gain understanding of the tight association of inflammatory pathways, including NF-κB, with the pathogenesis of neurodegenerative diseases. …”
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    Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling
  8. 1408
    “…Emerging evidences suggest that canonical Notch signaling may be involved in ischemic brain injury. …”
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    Electroacupuncture pretreatment induces tolerance against focal cerebral ischemia through activation of canonical Notch pathway
  9. 1409
    “…In this study, we focused on the effect of CD82 on the Wnt/β-catenin (canonical) pathway, which controls the cellular distribution of β-catenin. …”
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    CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of β-catenin in carcinoma cells
  10. 1410
    “…Functional intracellular Ca(2+) signaling is essential for the upregulation of the canonical mTOR-controlled autophagy pathway triggered by rapamycin or by nutrient deprivation. …”
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    Intracellular Ca(2+) signaling: A novel player in the canonical mTOR-controlled autophagy pathway
  11. 1411
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    An Evolutionary Screen Highlights Canonical and Noncanonical Candidate Antiviral Genes within the Primate TRIM Gene Family
  12. 1412
    “…Subtle, but statistically significant differences are seen in roll, slide and average propeller-twist values, between the dinucleotide steps of free RNA and protein bound RNA structures. Many non-canonical cross-strand and intra-strand hydrogen bonds were identified that can stabilise the RNA dinucleotide steps, among which YR steps show presence of many new unreported interactions. …”
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    Sequence dependent variations in RNA duplex are related to non-canonical hydrogen bond interactions in dinucleotide steps
  13. 1413
    “…In line with this, the considerable upregulation of Crumbs in boundary cells is not followed by a corresponding upregulation of its canonical binding partners. Our data are the first to suggest a mechanism controlling apical Crumbs localisation, which is independent of its conserved FERM- and PDZ-domain binding motifs.…”
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    Apical Localisation of Crumbs in the Boundary Cells of the Drosophila Hindgut Is Independent of Its Canonical Interaction Partner Stardust
  14. 1414
    “…This analysis was conducted to explore the association between 5 birth size measurements (weight, length and head, chest and mid-upper arm [MUAC] circumferences) as dependent variables and 10 maternal factors as independent variables using canonical correlation analysis (CCA). CCA considers simultaneously sets of dependent and independent variables and, thus, generates a substantially reduced type 1 error. …”
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    Canonical Correlation Analysis of Infant's Size at Birth and Maternal Factors: A Study in Rural Northwest Bangladesh
  15. 1415
    “…Rbc3a loss-of-function initially downregulates several canonical Wnt targets involved in EMT, but later Frizzled-7 accumulates at NC cell membranes, and nuclear B-catenin levels increase. …”
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    Rabconnectin-3a Regulates Vesicle Endocytosis and Canonical Wnt Signaling in Zebrafish Neural Crest Migration
  16. 1416
    “…Here we show that the C-terminal region of Gemin5 bears two non-canonical bipartite RNA-binding sites, encompassing amino acids 1297–1412 (RBS1) and 1383–1508 (RBS2). …”
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    Identification of novel non-canonical RNA-binding sites in Gemin5 involved in internal initiation of translation
  17. 1417
    “…In addition, to assess interrelations between NIRS and systemic variables, collected simultaneously, canonical correlation analysis (CCA) was employed. …”
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    Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO
  18. 1418
    “…Here we report a novel non-canonical tetra-modular nonribosomal peptide synthetase (NRPS) with microheterogenicity of all involved adenylation domains towards their respective substrates. …”
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    A Non-Canonical NRPS Is Involved in the Synthesis of Fungisporin and Related Hydrophobic Cyclic Tetrapeptides in Penicillium chrysogenum
  19. 1419
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    Replication stress by Py–Im polyamides induces a non-canonical ATR-dependent checkpoint response
  20. 1420
    “…Transient receptor potential canonical type 3 (TRPC3) channels are non-selective cation channels and regulate intracellular Ca(2+) concentration. …”
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    Transient Receptor Potential Canonical Type 3 Channels Control the Vascular Contractility of Mouse Mesenteric Arteries
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