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  1. 1541
    “…IFN-γ, known to promote non-canonical inflammasome activation, did not influence pyroptosis induction or IL-1β release from infected primary human macrophages. …”
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    Burkholderia pseudomallei triggers canonical inflammasome activation in a human primary macrophage-based infection model
  2. 1542
    “…The ubiquitous redox coenzyme nicotinamide adenine dinucleotide (NAD) acts as a non-canonical cap structure on prokaryotic and eukaryotic ribonucleic acids. …”
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    Extensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast
  3. 1543
    “…Remarkably, we showed the canonical autophagy factor ULK1 was cleaved through the catalytic activity of the viral proteinase 3C. …”
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    Coxsackievirus infection induces a non-canonical autophagy independent of the ULK and PI3K complexes
  4. 1544
    “…We find that cell-autonomous mutations within interneurons disrupts morphophysiological development of PV+INTs and results in the emergence of a non-canonical ‘intermediate spiking (IS)’ subset of PV+INTs. …”
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    Emergence of non-canonical parvalbumin-containing interneurons in hippocampus of a murine model of type I lissencephaly
  5. 1545
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    Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release
  6. 1546
    “…This study aimed to develop a tool to validate multivariety breed egg quality classification depending on quality-related internal and external traits using a discriminant canonical analysis approach. A flock of 60 Utrerana hens (Franciscan, White, Black, and Partridge) and a control group of 10 Leghorn hens were placed in individual cages to follow the traceability of the eggs and perform an individual internal and external quality assessment. …”
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    Discriminant Canonical Analysis as a Validation Tool for Multivariety Native Breed Egg Commercial Quality Classification
  7. 1547
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    Lithium: a potential therapeutic strategy in obsessive–compulsive disorder by targeting the canonical WNT/β pathway
  8. 1548
    “…While it is well known that canonical intermittent NRF2 activation protects against diabetes-induced tissue damage, little is known regarding the effects of prolonged non-canonical NRF2 activation in diabetes. …”
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    Non-canonical NRF2 activation promotes a pro-diabetic shift in hepatic glucose metabolism
  9. 1549
    “…To tackle this problem, we equipped the β-hairpin fold of a tryptophan zipper with pairs of non-canonical amino acids, one serving as a VET injector and one as a VET sensor in a femtosecond pump probe experiment. …”
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    Through bonds or contacts? Mapping protein vibrational energy transfer using non-canonical amino acids
  10. 1550
    “…The genetic code of mammalian cells can be expanded to allow the incorporation of non-canonical amino acids (ncAAs) by suppressing in-frame amber stop codons (UAG) with an orthogonal pyrrolysyl-tRNA synthetase (PylRS)/tRNA(Pyl)(CUA) (PylT) pair. …”
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    Identification of permissive amber suppression sites for efficient non-canonical amino acid incorporation in mammalian cells
  11. 1551
    “…Altogether, these findings reveal the non-canonical function of DGCR8 in DSB repair and suggest that radiation treatment may result in therapy-induced tumor radioresistance through ATM- and USP51-mediated activation and upregulation of DGCR8.…”
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    Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance
  12. 1552
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    TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism
  13. 1553
    “…Transient receptor potential canonical 1 (TRPC1) channel is the first cloned TRPC family protein. …”
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    Investigation of the effect of hyperthyroidism on endoplasmic reticulum stress and transient receptor potential canonical 1 channel in the kidney
  14. 1554
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    Non-canonical role for Lpar1-EGFP subplate neurons in early postnatal mouse somatosensory cortex
  15. 1555
    “…When androgen was not deprived, we found evidence of non-canonical SMO signaling through the SRC kinase. After short-term androgen deprivation canonical HH-GLI signaling was activated, but we found little evidence of canonical HH-GLI signaling activity in androgen-independent prostate cancer cells. …”
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    SHH-N non-canonically sustains androgen receptor activity in androgen-independent prostate cancer cells
  16. 1556
    por Ke, Fengchun, Kong, Wei, Wang, Shuaiqun
    Publicado 2021
    “…Imaging genetics combines neuroimaging and genetics to assess the relationships between genetic variants and changes in brain structure and metabolism. Sparse canonical correlation analysis (SCCA) models are well-known tools for identifying meaningful biomarkers in imaging genetics. …”
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    Identifying Imaging Genetics Biomarkers of Alzheimer’s Disease by Multi-Task Sparse Canonical Correlation Analysis and Regression
  17. 1557
    por Ding, Yong
    Publicado 2021
    “…To reduce the high dimension of the original image as well as bidimensional intrinsic mode functions, multiset canonical correlations analysis is adopted to fuse them as a unified feature vector. …”
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    Multiset Canonical Correlations Analysis of Bidimensional Intrinsic Mode Functions for Automatic Target Recognition of SAR Images
  18. 1558
    “…We found that >98% of HA-tagged MOP contain the UMB-3 epitope indicating that virtually all MOP expressed in the mouse brain exhibit the canonical amino acid sequence.…”
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    HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants
  19. 1559
    por El Baba, Ranim, Herbein, Georges
    Publicado 2021
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    Immune Landscape of CMV Infection in Cancer Patients: From “Canonical” Diseases Toward Virus-Elicited Oncomodulation
  20. 1560
    “…In the complex, the canonical HK homodimerization interface is replaced by a strikingly similar heterodimeric interface between RetS and GacS. …”
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    RetS inhibits Pseudomonas aeruginosa biofilm formation by disrupting the canonical histidine kinase dimerization interface of GacS
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