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  1. 1621
    “…A previous high-throughput study inferred that R. toruloides possesses a non-canonical l-arabinose and d-xylose metabolism proceeding through d-arabitol and d-ribulose. …”
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    Non-canonical d-xylose and l-arabinose metabolism via d-arabitol in the oleaginous yeast Rhodosporidium toruloides
  2. 1622
    “…Recently it has also become evident that regulatory regions of the genome are enriched with non-canonical DNA structures. These include G-quadruplexes (G4s) which form on guanine-rich stretches of single-stranded DNA and iMotifs (iMs) on the complementary strand, and are reported to bind various proteins which presumably regulate and mediate their actions. …”
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    OR2801 Novel Cis-Regulatory Mechanisms Of Lhb Transcription By Non-Coding RNAs And Non-Canonical DNA Structures
  3. 1623
    “…Using a comprehensive series of biochemical, pharmacological, and genetic approaches, we show that lysosome damage induces non-canonical autophagy and Conjugation of ATG8s to Single Membranes (CASM). …”
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    Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy
  4. 1624
    “…While recognition of microbe-associated molecular patterns can activate IRE1α, it is unclear whether this depends on the canonical role of IRE1α in detecting misfolded proteins. …”
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    Non-canonical activation of IRE1α during Candida albicans infection enhances macrophage fungicidal activity
  5. 1625
    “…This response may have a possible association with the dysregulation of non-canonical pathways, including housekeeping functions in addition to the conventional antiviral immune response mediated by the T cell subpopulation. …”
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    Dysregulated metal ion homeostasis underscores non-canonical function of CD8(+) T cell during COVID-19
  6. 1626
    “…The results showed that our methods obtained better or comparable canonical correlation coefficients (CCCs) and better feature subsets than benchmarks. …”
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    inMTSCCA: An Integrated Multi-task Sparse Canonical Correlation Analysis for Multi-omic Brain Imaging Genetics
  7. 1627
    “…A crucial step in these therapeutic technologies is the oral administration of non‐canonical amino acids (ncAAs) to control pathogen growth and therapeutic protein levels in vivo. …”
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    Use of non‐canonical amino acids in genetic code expansion‐based therapeutics: Effects on mouse gut microbiota
  8. 1628
    “…We identified 46 non-canonical GRHL1 binding sites, which were not found by a conventional PWM approach. …”
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    Discovery of a non-canonical GRHL1 binding site using deep convolutional and recurrent neural networks
  9. 1629
    “…If there is more than one outcome variable, the analysis must then be repeated, and the results combined in some arbitrary fashion. In contrast, Canonical Correlation Analysis (CCA) has the ability to analyze multiple outcomes at the same time. …”
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    Exploring cancer register data to find risk factors for recurrence of breast cancer – application of Canonical Correlation Analysis
  10. 1630
    por Nacusi, Lucas P, Sheaff, Robert J
    Publicado 2006
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    Akt1 sequentially phosphorylates p27(kip1 )within a conserved but non-canonical region
  11. 1631
    “…Our data indicate a bifurcation in the so-called canonical WNT-signaling pathway to regulate microtubule stability.…”
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    A divergent canonical WNT-signaling pathway regulates microtubule dynamics: Dishevelled signals locally to stabilize microtubules
  12. 1632
    “…We have uncovered a new noncanonical pathway through which Wnt-5a antagonizes the canonical Wnt pathway by promoting the degradation of β-catenin. …”
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    Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation
  13. 1633
    “…We previously demonstrated that, in addition to the canonical WNT/β-catenin pathway, WNT signaling activates the extracellular signal-regulated kinase 1/2 (ERK1/2) pathway in mouse mammary epithelial cells via epidermal growth factor receptor (EGFR) transactivation. …”
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    Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation
  14. 1634
    “…Using Her2(+)/ER(-) breast cancer cells, we show that Her2 activates NF-κB through the canonical pathway which, surprisingly, involves IKKα. …”
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    Her2 Activates NF-κB and Induces Invasion Through the Canonical Pathway Involving IKKα
  15. 1635
    “…CONCLUSIONS: Taken together, these results demonstrate the unexpected role of IKKα in the canonical NF-κB pathway triggered by peptidoglycan recognition during bacterial infection. …”
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    IKKα Contributes to Canonical NF-κB Activation Downstream of Nod1-Mediated Peptidoglycan Recognition
  16. 1636
    “…The highly conserved pentaloop of SL2 is stacked on 5‐bp stem and adopts a canonical CUYG tetraloop fold with the 3′ nucleotide (U51) flipped out of the stack. …”
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    The solution structure of coronaviral stem‐loop 2 (SL2) reveals a canonical CUYG tetraloop fold
  17. 1637
    “…Site 1, which is non-canonical, binds nucleotide tightly but is not hydrolytic. …”
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    Mutant cycles at CFTR’s non-canonical ATP-binding site support little interface separation during gating
  18. 1638
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    Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I Tax-mediated tumorigenesis
  19. 1639
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    Human imprinted retrogenes exhibit non-canonical imprint chromatin signatures and reside in non-imprinted host genes
  20. 1640
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    CIN85 drives B cell responses by linking BCR signals to the canonical NF-κB pathway
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