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  1. 1941
    “…Mammalian SWI/SNF chromatin remodeling complexes exist in three distinct, final-form assemblies: canonical BAF (cBAF), PBAF, and a newly-characterized non-canonical complex, ncBAF. …”
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    A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation
  2. 1942
    “…Analysis of this dataset has revealed a unique non-canonical mechanism of JAK/STATs in neurons as differential gene expression mediated by STAT3 is not solely dependent upon phosphorylation at residue 705 and may involve a BDNF-induced interaction of STAT3 with Heterochromatin Protein 1 alpha (HP1α). …”
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    Evidence for a non-canonical JAK/STAT signaling pathway in the synthesis of the brain’s major ion channels and neurotransmitter receptors
  3. 1943
    “…Genome-wide, copy number driven gene expression was enriched for pathways characteristic of the CMS2-epithelial/canonical subtype, including DNA repair and cell cycle progression. …”
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    Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains
  4. 1944
    “…Endothelial progenitor cells (EPCs) contribute to blood vessel formation. Canonical Wnt signaling plays an important role in physiological and pathological angiogenesis and EPC fate regulation. …”
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    Canonical Wnt Signaling Promotes Neovascularization Through Determination of Endothelial Progenitor Cell Fate via Metabolic Profile Regulation
  5. 1945
    “…Here, we generated a novel mouse strain, which enables cell-type-specific labelling of newly synthesised proteins with non-canonical amino acids (NCAAs) by genetically restricting the expression of the mutant tRNA synthetase, NLL-MetRS, to hippocampal neurons. …”
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    Cell-specific non-canonical amino acid labelling identifies changes in the de novo proteome during memory formation
  6. 1946
    “…In our study, we come up with a novel and valid method to accomplish muscle artifact removal from EEG by using the combination of singular spectrum analysis (SSA) and canonical correlation analysis (CCA), which is named as SSA-CCA. …”
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    Removal of EMG Artifacts from Multichannel EEG Signals Using Combined Singular Spectrum Analysis and Canonical Correlation Analysis
  7. 1947
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    A non-canonical role for p27(Kip1) in restricting proliferation of corneal endothelial cells during development
  8. 1948
    “…Aging, cancer, and longevity have been linked to intracellular Ca(2+) signaling and nociceptive transient receptor potential (TRP) channels. We found that TRP canonical 7 (TRPC7) is a nociceptive mechanoreceptor and that TRPC7 channels specifically mediate the initiation of ultraviolet B (UVB)‐induced skin aging and tumor development due to p53 gene family mutations. …”
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    Nociceptive transient receptor potential canonical 7 (TRPC7) mediates aging‐associated tumorigenesis induced by ultraviolet B
  9. 1949
    “…Then, individuals were biometrically clustered into populations after a stepwise canonical discriminant analysis (CDA) computing interpopulation Mahalanobis distances. …”
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    Sexual Dimorphism and Breed Characterization of Creole Hens through Biometric Canonical Discriminant Analysis across Ecuadorian Agroecological Areas
  10. 1950
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    Author Correction: Canonical germinant receptor is dispensable for spore germination in Clostridium botulinum group II strain NCTC 11219
  11. 1951
    por Meerson, Ari
    Publicado 2020
    “…Next generation sequencing evidence and structural prediction suggest that miR-4443 is not produced via the canonical Drosha–Exportin 5–Dicer pathway of microRNA biogenesis. …”
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    Leptin-Responsive MiR-4443 Is a Small Regulatory RNA Independent of the Canonic MicroRNA Biogenesis Pathway
  12. 1952
    “…In the most recently proposed non-canonical model, the active form of Bcl-xL employs its N-terminal BH4 helix to bind and block its pro-apoptotic target. …”
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    Conformational Switching in Bcl-xL: Enabling Non-Canonic Inhibition of Apoptosis Involves Multiple Intermediates and Lipid Interactions
  13. 1953
    “…Since both N-terminal myristoylated and C-terminal prenylated proteins use a Singly Lipidated Polybasic Terminus (SLIPT) for CaM binding, we propose these polybasic lipopeptide elements comprise a non-canonical CaM-binding motif.…”
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    A Non-Canonical Calmodulin Target Motif Comprising a Polybasic Region and Lipidated Terminal Residue Regulates Localization
  14. 1954
    “…Aims: We aimed to validate the pathogenicity of genetic variants identified in inherited retinal dystrophy (IRD) patients, which were located in non-canonical splice sites (NCSS). Methods: After next generation sequencing (NGS) analysis (target gene panels or whole exome sequencing (WES)), NCSS variants were prioritized according to in silico predictions. …”
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    Increasing the Genetic Diagnosis Yield in Inherited Retinal Dystrophies: Assigning Pathogenicity to Novel Non-canonical Splice Site Variants
  15. 1955
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    A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay
  16. 1956
    “…The selective enrichment of non-canonical RNA-editing events within MNR adjacency provides a negative evidence against their authenticity. …”
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    Non-canonical RNA-DNA differences and other human genomic features are enriched within very short tandem repeats
  17. 1957
    “…The 2PA properties of these new non-canonical chromophores (nCCs) were determined in vacuum, i.e., without taking into account the protein environment. …”
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    Two-Photon Absorption Cross-Sections in Fluorescent Proteins Containing Non-canonical Chromophores Using Polarizable QM/MM
  18. 1958
    por Mirza, Zeenat, Abdel-dayem, Umama A.
    Publicado 2020
    “…The top upregulated genes were FOS, EGR1, ZFP36, JUNB, APOD, CST1, GPX3, and PER1, and the top downregulated ones were DIO2, CPM, OLFM4, PALLD, BAG5, TOP2A, PKP4, CDC20B, and SNTN. The most perturbed canonical pathways were mitotic roles of Polo-like kinase, role of Checkpoint kinase proteins in cell cycle checkpoint control, and ATM signaling. …”
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    Uncovering Potential Roles of Differentially Expressed Genes, Upstream Regulators, and Canonical Pathways in Endometriosis Using an In Silico Genomics Approach
  19. 1959
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    Gemigliptin Inhibits Interleukin-1β–Induced Endothelial-Mesenchymal Transition via Canonical-Bone Morphogenetic Protein Pathway
  20. 1960
    por Krotko, Dmytro G.
    Publicado 2020
    “…The atomic ring invariant and the Modified CANON algorithm allow us to create a rigorous procedure for the generation of canonical SMILES which can be used for accurate and fast structural searching in large chemical databases.…”
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    Atomic ring invariant and Modified CANON extended connectivity algorithm for symmetry perception in molecular graphs and rigorous canonicalization of SMILES
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