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145661por Blouhos, K., Boulas, K.A., Paraskeva, A., Kariotis, I., Barettas, N., Hatzigeorgiadis, A.“…Tumors characterized most commonly with pancreatic involvement are lymphoma, renal cell and lung carcinomas. PRESENTATION OF CASE: A 76-year-old female patient with obstructive jaundice as the primary symptom and inguinal lymphadenopathy is presented. …”
Publicado 2018
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145662“…Genetic alterations in key signaling pathways found in early pancreatic lesions are pivotal for the development and progression of pancreatic intraepithelial neoplastic lesions into invasive carcinomas. More than 90% of PDAC tumors harbor driver mutations in K-Ras that activate various downstream effector-signaling pathways, including the phosphoinositide-3-kinase (PI3K) pathway. …”
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145663por Fukushima, Shoji, Shibata, Masa‐Aki, Hirose, Masao, Kato, Toshio, Tatematsu, Masae, Ito, Nobuyuki“…The hepatocarcinogen group in combination with various nitroso compounds increased the incidences of liver hyperplastic nodules and hepatocellular carcinomas. In contrast, incidences were clearly reduced when the hepatocarcinogens and/or the nitroso compounds were administered in combination with the antioxidants. …”
Publicado 1991
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145664por Kagawa, Masataka, Hakoi, Kazuo, Yamamoto, Atsushi, Futakuchi, Mitsuru, Hirose, Masao“…This putative preneoplastic lesion might then progress to produce carcinomas.…”
Publicado 1993
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145665por Ito, Akihiro, Okamoto, Taro, Fujimoto, Nariaki, Ogundigie, Peter Osa, Watanabe, Hiromitsu“…The influence of 17β‐estradiol (E2) and prolactin was studied on N‐methyl‐N‐nitrosourea (MNU)‐induced mammary carcinomas (MCAs) in rats. MNU was intravenously injected once into seven‐week‐old female F344 rats at a dose of 50 mg/kg body weight. …”
Publicado 1994
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145666por Ando‐Lu, Jin, Takahashi, Masakazu, Imai, Shigeru, Ishihara, Roza, Kitamura, Tsuyoshi, Iijima, Tetsuo, Takano, Satoshi, Nishiyama, Kan, Suzuki, Kenji, Maekawa, Akihiko“…No tumors other than uterine carcinomas were induced by ENNG and the carcinogen treatment did not affect the endocrine environment of rats, persistent estrus appearing at 6 months after the start and increasing with age in both groups. …”
Publicado 1994
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145667“…In female rats, dose‐related increases in hyperplasia of the pelvis transitional epithelium, and 2 carcinomas were discovered. Urinary bladder: papillomas of the transitional epithelium were seen in 2 low‐dose male and in 1 low‐dose female rats. …”
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145668“…We previously demonstrated that tumorigenic variants from this cell line produced moderately differentiated hepatocellular carcinomas in nude mice. However, it has remained unclear whether the parental MLEC10 cells represent immortalized hepatocytes or so‐called oval cells, both of which may serve as precursors for hepatocellular neoplasms. …”
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145669por Furukawa, Fumio, Nishikawa, Akiyoshi, Ishiwata, Hitoshi, Takahashi, Michihito, Hayashi, Yuzo, Hirose, Masao“…Treatment with fish meal dose‐dependently increased the incidences and multiplicities of atypical tubules, adenomas and renal cell carcinomas in sodium nitrite‐treated males. Females were less susceptible than males for renal tumor induction. …”
Publicado 2000
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145670por Haga, Shunsuke, Emi, Mitsuru, Hirano, Akira, Utada, Yoshihito, Kajiwara, Tetsuro, Akiyama, Futoshi, Sakamoto, Goi, Takahashi, Kaoru, Tada, Takashi, Kasumi, Fujio, Miki, Yoshio, Nakamura, Yusuke“…To identify specific allelic losses that might correlate with postoperative mortality of patients with node‐positive breast carcinomas, we examined tumors from a cohort of 263 such patients, who were followed clinically for 5 years postoperatively, for allelic losses among 18 microsatellite markers. …”
Publicado 2001
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145671por Dai, Yuanqing, Li, Dongjie, Chen, Xiong, Tan, Xinji, Gu, Jie, Chen, Mingquan, Zhang, Xiaobo“…Circular RNAs (circRNAs) are a class of endogenous non-coding RNAs (ncRNAs) stably expressed in cells and involved in a series of carcinomas. However, few research studies have reported on the role of circRNAs in PCa. …”
Publicado 2018
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145672Publicado 2011“…The fistulas were caused by esophageal (n=26), bronchogenic (n=11), and thyroid (n=1) carcinomas. RESULTS: Forty-six fistulas were found in 38 patients. …”
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145673“…A total of 216 blood samples were collected, including those from 36 gastric cancer patients, 55 healthy controls and 125 patients with other carcinomas, and gene expression profiles were examined using an Affymetrix Gene Profiling microarray. …”
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145674“…CBM complex components have gained considerable interest due to the dramatic effects of associated mutations in causing severe lymphomas, immunodeficiencies, carcinomas and inflammatory disease. While MALT1 and BCL10 are ubiquitous proteins, the CARD-containing proteins differ in their tissue expression. …”
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145675“…Thereafter, we revisit the mTOR pathway in renal physiology to conclude with the advances, drawbacks, and challenges regarding the use of mTOR inhibitors, in a translational perspective, in four classes of renal diseases: kidney transplantation, polycystic kidney diseases, renal carcinomas, and diabetic nephropathy.…”
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145676por Zhang, Quxia, Xu, Chunwei, Wang, Wenxian, Wu, Meijuan, Zhu, Youcai, Zhuang, Wu, Du, Kaiqi, Huang, Yunjian, Chen, Yanping, Wu, Biao“…BACKGROUND: RET rearrangements have been reported in 30% of papillary thyroid carcinomas and 1–2% of non-small cell lung cancer (NSCLC). …”
Publicado 2018
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145677por Schleifer, Robert J., Li, Shuchun, Nechtman, Wyatt, Miller, Eric, Bai, Shan, Sharma, Ashok, She, Jin-Xiong“…While KLHL5 expression shows marginal dysregulation in cancer, other KLHLs exhibit significant dysregulation in all cancer types, and exceptionally in renal carcinomas. This study advocates for further study of KLHLs as potential alternative therapeutic targets, since while KLHL5 is a novel gene impacting anticancer drug effects, others may have a similar impact on drug effect while having greater potential as diagnostic or prognostic markers.…”
Publicado 2018
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145678por Hwang, Su-Yeon, Choi, Eun-Sil, Kim, Young-Sun, Gim, Bo-Eun, Ha, Mina, Kim, Hae-Young“…Health outcomes such as leukemia, low birth weight, cataracts, and thumb carcinomas were also reported. In a few studies examining health effects related to dental X-ray exposure, possibly increased risks of meningioma and thyroid cancer were suggested. …”
Publicado 2018
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145679por Jantscheff, Peter, Beshay, Janette, Lemarchand, Thomas, Obodozie, Cynthia, Schächtele, Christoph, Weber, Holger“…Nine outgrowing primary tumors were histologically characterized either as adenocarcinomas, histiocytic carcinomas, or lymphomas. Growth of the tumor pieces after re-transplantation displayed model heterogeneity. …”
Publicado 2019
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145680por Terakawa, Jumpei, Serna, Vanida Ann, Taketo, Makoto Mark, Daikoku, Takiko, Suarez, Adrian A., Kurita, Takeshi“…Endometrioid endometrial carcinomas (EECs) carry multiple driver mutations even when they are low grade. …”
Publicado 2019
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