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  1. 145781
    “…We demonstrate that curcuphenol induces the expression of the APM components, TAP-1 and MHC-I molecules, in cell lines derived from both metastatic prostate and lung carcinomas. Turmeric and curcumins that contain curcuphenol have long been utilized not only as a spice in the preparation of food, but also in traditional medicines for treating cancers. …”
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    A novel cell-based screen identifies chemical entities that reverse the immune-escape phenotype of metastatic tumours
  2. 145782
    “…HM-10/10 holds promise as a new agent to address the international women’s health crisis of epithelial carcinomas of the ovary and colon.…”
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    Stability Characterization of the Novel Anti-Cancer HM-10/10 HDL-Mimetic Peptide
  3. 145783
    “…In human single-cell cRNA-Seq (scRNA-Seq) data sets, we discovered that SELENOP expression rose as normal colon stem cells transformed into adenomas that progressed into carcinomas. We next examined the effects of Selenop KO in a mouse adenoma model that involved conditional, intestinal epithelium-specific deletion of the tumor suppressor adenomatous polyposis coli (Apc) and found that Selenop KO decreased colon tumor incidence and size. …”
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    SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions
  4. 145784
    “…Using high-parameter flow cytometry, we identified an accumulation of tissue-resident lymphocytes including tissue-resident NK (trNK) cells and CD8(+) tissue-resident memory T (T(RM)) cells toward the center of human non-small cell lung carcinomas (NSCLC). Chemokine receptor expression patterns indicated different modes of tumor-infiltration and/or residency between trNK cells and CD8(+) T(RM) cells. …”
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    Accumulation of tissue-resident natural killer cells, innate lymphoid cells, and CD8(+) T cells towards the center of human lung tumors
  5. 145785
    “…Background: Melanoma is one of the most malignant skin carcinomas with high metastatic potential. Increasing evidence has demonstrated that β-tubulin 4A (TUBB4A) plays a key role in the development and progression of several types of human cancer. …”
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    Identification of TUBB4A as a Prognostic Biomarker of Melanoma by Transcriptomic Data and In Vitro Experiments
  6. 145786
    “…Immunohistological analysis revealed that CCDC85A is expressed to varying degrees by cancer cells and CAFs in gastric and pancreatic carcinomas. Downregulation of CCDC85A in cancer cells revealed that these cells are vulnerable to endoplasmic reticulum (ER) stress induced by thapsigargin or tunicamycin, which were ameliorated after addback of CCDC85A. …”
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    CCDC85A is regulated by miR-224-3p and augments cancer cell resistance to endoplasmic reticulum stress
  7. 145787
    “…Subgroup analysis also confirmed that the above findings still hold true in patients with esophageal cancer, gastric cancer, and hepatocellular carcinomas. CONCLUSION: The PNI were reliable predictors of outcomes in GIC patients treated with ICIs.…”
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    Prognostic nutritional index as a prognostic biomarker for gastrointestinal cancer patients treated with immune checkpoint inhibitors
  8. 145788
    por Chen, Yong-Hui, Zhang, Ying-Qiang
    Publicado 2020
    “…MATERIAL AND METHODS: Multiple databases including PubMed, Springer, EMBASE, Ovid, and the Cochrane Library were searched with the keywords “thyroid cancer OR thyroid carcinomas”, “cervical lymph nodes”, “metastatic OR metastasis”, and “ultrasonography OR ultrasound OR CT OR computed tomography” in June 2018. …”
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    Diagnostic potential of ultrasonography and computed tomography in differentiating cervical lymph node metastasis of thyroid cancer: a systematic review and meta-analysis
  9. 145789
    “…The majority of tumors (48/52, 86.2%) were clear-cell carcinomas. According to the glomerular filtration rate postoperatively and 12 months’ posttreatment, adequate renal function was preserved in all patients. …”
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    Radiofrequency-assisted, laparoscopic, clampless partial nephrectomy in patients with low-complexity small renal tumors: A retrospective cohort study
  10. 145790
    “…The pathological types were all endometrioid carcinomas. PD-1 inhibitors were selected from camrelizumab or pembrolizumab, and antiangiogenic targeted agents were selected from apatinib or anlotinib. …”
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    A case series on the efficacy and safety of a PD-1 inhibitor combined with antiangiogenic agents in the treatment of recurrent MSI-H endometrial cancer
  11. 145791
    “…Methods: Immunohistochemistry was used to assess CD105 expression in invasive ductal breast carcinomas (n = 342), analyzing its association with clinical and pathological characteristics. …”
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    CD105 expression in cancer-associated fibroblasts: a biomarker for bone metastasis in early invasive ductal breast cancer patients
  12. 145792
    “…Because she had previously been diagnosed with colorectal and breast carcinomas at an early age, we performed a comprehensive genetic analysis to identify molecular alterations present in her background that unveiled multiple malignancy predispositions. …”
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    Malignant Perivascular Epithelioid Cell Tumor (PEComa) of the Uterus as Part of the Hereditary Cancer Syndrome: A Case Diagnosed with Multiple Malignancies
  13. 145793
    “…Approximately 20–30% of endometrial carcinomas (EC) are characterized by mismatch repair (MMR) deficiency (dMMR) or microsatellite instability (MSI), and their testing has become part of the routine diagnosis. …”
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    Comparison of Methods for Testing Mismatch Repair Status in Endometrial Cancer
  14. 145794
    “…Supratentorial tumors were the most common (50%), and the most common histological types were glial tumors3(29.33), carcinomas (26%) and meningiomas (10%). Therapeutic modalities were surgery, radiotherapy and chemotherapy. …”
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    OTHER-14 NEURO-ONCOLOGY STAFF MEETING: EXPERIENCE OF 4 YEARS
  15. 145795
    “…Cisplatin treatment is effective against several types of carcinomas. However, it frequently leads to kidney injury, which warrants effective prevention methods. …”
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    Valproic acid treatment attenuates cisplatin‐induced kidney injury by suppressing proximal tubular cell damage
  16. 145796
    “…Benign neoplasms accounted for a significant portion (14.3%) of SRM. Renal cell carcinomas (RCCs) were the most common diagnoses (69.6%) as expected. …”
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    The success rate of small renal mass core needle biopsy and its impact on lowering benign resection rate
  17. 145797
    “…These molecules have been linked to a worse prognosis in right-sided colon and rectal carcinomas. An analysis revealed an association between eight novel miRNAs and 81 targets, mostly cancer-related genes, with varying expression based on tumor location. …”
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    Discovery of Novel miRNAs in Colorectal Cancer: Potential Biological Roles and Clinical Utility
  18. 145798
    “…OBJECTIVE: To explore the feasibility, safety and effectiveness of the 450-nm blue diode laser (BL), novel blue laser in the treatment of upper tract urothelial carcinomas (UTUCs) and other lesions in a porcine model. …”
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    450-nm blue diode laser: a novel medical apparatus for upper tract urothelial lesions
  19. 145799
    “…CONCLUSION: Our data reveal that morphologically normal tissue adjacent to breast carcinomas has not undergone significant gene expression changes when compared to breast reduction tissue, and provide an important gene expression dataset for comparative studies of tumor expression profiles.…”
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    Gene expression signatures of morphologically normal breast tissue identify basal-like tumors
  20. 145800
    “…BACKGROUND: Mutational inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene has been linked to hereditary as well as sporadic clear cell renal carcinomas. The product of the VHL gene, pVHL, acts to target hypoxia-inducible factor alpha (HIF-α) subunits for ubiquitination and subsequent degradation. …”
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    HIF-2α downregulation in the absence of functional VHL is not sufficient for renal cell differentiation
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