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146741por Konstandiadou, Ioanna, Mastoraki, Aikaterini, Kotsilianou, Olympia, Karakitsos, Petros, Athanasas, George, Smyrniotis, Vasilios, Arkadopoulos, Nikolaos“…OBJECTIVE: Ductal lavage (DL) involves evaluation of the ductal system of the breast for detection of intra-ductal carcinomas and precursor lesions by collecting breast epithelial cells using a small-gauge catheter inserted into a ductal orifice on the nipple. …”
Publicado 2012
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146742por Phillips, Kevin G., Kolatkar, Anand, Rees, Kathleen J., Rigg, Rachel, Marrinucci, Dena, Luttgen, Madelyn, Bethel, Kelly, Kuhn, Peter, McCarty, Owen J. T.“…Clinical studies have demonstrated that CTCs circulate in the blood of patients with metastatic disease across the major types of carcinomas, and that the number of CTCs in peripheral blood is correlated with overall survival in metastatic breast, colorectal, and prostate cancer. …”
Publicado 2012
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146743por Stenvold, Helge, Donnem, Tom, Andersen, Sigve, Al-Saad, Samer, Valkov, Andrej, Pedersen, Mona Irene, Busund, Lill-Tove, Bremnes, Roy M“…METHODS: From 335 unselected stage I to IIIA NSCLC carcinomas, duplicate tumor and tumor-associated stromal cores were collected in tissue microarrays (TMAs). …”
Publicado 2014
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146744“…METHODS: Epigenetic regulation of DNMT1 was assessed in 85 invasive ductal carcinomas from BRCA1 mutation carriers. Association between clinicopathological features and DNMT1 promoter methylation was determined using Fisher’s exact test. …”
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146745por Cho, Hwa Jin, Kim, Hanna, Kwak, Yoon Jin, Seo, Jeong Wook, Paek, Sun Ha, Sohn, Chul-Ho, Yun, Jung Min, Kim, Da Seu Ran, Kang, Peter, Park, Peom, Park, Sung-Hye“…The lesions were categorized as: PAs (n = 422, 83.4%), Rathke's cleft cysts (RCCs) (n = 54, 10.6%), inflammatory lesions (n = 8, 1.6%), meningiomas (n = 4), craniopharyngiomas (n = 4), granular cell tumors (n = 1), metastatic renal cell carcinomas (n = 2), germinomas (n = 1), ependymomas (n = 1), and unsatisfactory specimens (n = 9, 1.8%). …”
Publicado 2014
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146746por Chung, Joon-Yong, Braunschweig, Till, Hong, Seung-Mo, Kwon, David S, Eo, Soo-Heang, Cho, HyungJun, Hewitt, Stephen M“…The VEGF expression level of well differentiated colon cancer was significantly higher than those with moderately and poorly differentiated carcinomas by immunohistochemistry (P = 0.04) and well-based RPPA (P = 0.04). …”
Publicado 2014
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146747por Huu, Nguyen Tho, Yoshida, Hideki, Umegawachi, Takanari, Miyata, Seiji, Yamaguchi, Masamitsu“…Moreover, OSCP1 is known as a tumor suppressor gene that is frequently down-expressed in nasopharyngeal carcinomas and acute myeloid leukemia. However, the underlying mechanisms of action remain unclear and the subcellular localization of OSCP1 has yet to be determined in detail. …”
Publicado 2014
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146748por Kim, Sung Mo, Heo, Suk Hee, Kim, Jin Woong, Lim, Hyo Soon, Shin, Sang Soo, Jeong, Yong Yeon, Kang, Heoung Keun“…The contrast-to-noise ratios (CNRs) of the hepatocellular carcinomas (HCC) were calculated. Finally, two experienced radiologists were independently asked to identify, if any, HCCs in the liver on the images and score the image quality in terms of the presence of artifacts and the proper enhancement of the liver, aorta, portal vein, hepatic vein, hepatic artery, spleen, pancreas, and kidney. …”
Publicado 2014
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146749por Xu, Tong-peng, Huang, Ming-de, Xia, Rui, Liu, Xin-xin, Sun, Ming, Yin, Li, Chen, Wen-ming, Han, Liang, Zhang, Er-bao, Kong, Rong, De, Wei, Shu, Yong-qian“…The clinical role of FENDRR in carcinomas remains yet to be found. METHOD: Real-time polymerase chain reaction (PCR) was used to examine FENDRR expression in gastric cancer cell lines/tissues compared with normal epithelial cells/adjacent non-tumorous tissues. …”
Publicado 2014
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146750por Shiraishi, Yuichi, Fujimoto, Akihiro, Furuta, Mayuko, Tanaka, Hiroko, Chiba, Ken-ichi, Boroevich, Keith A., Abe, Tetsuo, Kawakami, Yoshiiku, Ueno, Masaki, Gotoh, Kunihito, Ariizumi, Shun-ichi, Shibuya, Tetsuo, Nakano, Kaoru, Sasaki, Aya, Maejima, Kazuhiro, Kitada, Rina, Hayami, Shinya, Shigekawa, Yoshinobu, Marubashi, Shigeru, Yamada, Terumasa, Kubo, Michiaki, Ishikawa, Osamu, Aikata, Hiroshi, Arihiro, Koji, Ohdan, Hideki, Yamamoto, Masakazu, Yamaue, Hiroki, Chayama, Kazuaki, Tsunoda, Tatsuhiko, Miyano, Satoru, Nakagawa, Hidewaki“…In this study, we performed integrated and comparative analyses of whole genomes and transcriptomes of 22 hepatitis B virus (HBV)-related hepatocellular carcinomas (HCCs) and their matched controls. Comparison of whole genome sequence (WGS) and RNA-Seq revealed much evidence that various types of genomic mutations triggered diverse transcriptional changes. …”
Publicado 2014
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146751por Maebayashi, Toshiya, Abe, Katsumi, Aizawa, Takuya, Sakaguchi, Masakuni, Ishibash, Naoya, Fukushima, Shoko, Honma, Taku, Kusumi, Yoshiaki, Matsui, Tsuyoshi, Kawata, Nozomu“…The specimen showed a mixed pattern of conventional prostatic and neuroendocrine carcinomas. CONCLUSION: We herein report a case with neuroendocrine differentiation (NED), along with a review of the relevant literature, including histopathological findings. …”
Publicado 2015
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146752por Warth, A, Cortis, J, Soltermann, A, Meister, M, Budczies, J, Stenzinger, A, Goeppert, B, Thomas, M, Herth, F J F, Schirmacher, P, Schnabel, P A, Hoffmann, H, Dienemann, H, Muley, T, Weichert, W“…Results were validated in two independent cohorts of 233 squamous cell carcinomas (SQCC) and 184 adenocarcinomas (ADC). RESULTS: Proliferation index (overall mean: 40.7%) differed significantly according to histologic subtypes with SQCC showing a mean PI (52.8%) twice as high as ADC (25.8%). …”
Publicado 2014
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146753por Shibutani, Masatsune, Maeda, Kiyoshi, Nagahara, Hisashi, Ohtani, Hiroshi, Iseki, Yasuhito, Ikeya, Tetsuro, Sugano, Kenji, Hirakawa, Kosei“…BACKGROUND: The preoperative prognostic nutritional index (PNI) has been reported to correlate with the prognosis in patents with various carcinomas. However, the prognostic significance of the postoperative PNI is unknown. …”
Publicado 2015
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146754por Liu, Xiao, Wang, Ji-Hui, Li, Shun, Li, Lin-Lin, Huang, Min, Zhang, Yong-Hong, Liu, Yang, Yang, Yuan-Tao, Ding, Rui, Ke, Yi-Quan“…Notably, HDAC3 is overexpressed in the majority of carcinomas. However, thus far, no data are available to support the role of HDAC3 in VM. …”
Publicado 2015
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146755por Martínez, Ramón, Stühmer, Walter, Martin, Sabine, Schell, Julian, Reichmann, Andrea, Rohde, Veit, Pardo, Luis“…We also investigated Kv10.1 expression in the corresponding primary carcinomas of metastases patients. RESULTS: We observed positive Kv10.1 expression in 85.3 % of the brain metastases and in 77.5 % of GBMs. …”
Publicado 2015
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146756por Wu, Liang, Zhang, Xiaolong, Zhao, Zhikun, Wang, Ling, Li, Bo, Li, Guibo, Dean, Michael, Yu, Qichao, Wang, Yanhui, Lin, Xinxin, Rao, Weijian, Mei, Zhanlong, Li, Yang, Jiang, Runze, Yang, Huan, Li, Fuqiang, Xie, Guoyun, Xu, Liqin, Wu, Kui, Zhang, Jie, Chen, Jianghao, Wang, Ting, Kristiansen, Karsten, Zhang, Xiuqing, Li, Yingrui, Yang, Huanming, Wang, Jian, Hou, Yong, Xu, Xun“…BACKGROUND: Viral infection causes multiple forms of human cancer, and HPV infection is the primary factor in cervical carcinomas. Recent single-cell RNA-seq studies highlight the tumor heterogeneity present in most cancers, but virally induced tumors have not been studied. …”
Publicado 2015
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146757por Dibb, M., Han, N., Choudhury, J., Hayes, S., Valentine, H., West, C., Sharrocks, AD, Ang, Yeng S.“…FOXM1 is overexpressed in a large proportion of gastric carcinomas at the protein level and FOXM1 and PLK1 are concomitantly overexpressed at the mRNA level in this cancer type. …”
Publicado 2015
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146758por Kanu, N, Grönroos, E, Martinez, P, Burrell, R A, Yi Goh, X, Bartkova, J, Maya-Mendoza, A, Mistrík, M, Rowan, A J, Patel, H, Rabinowitz, A, East, P, Wilson, G, Santos, C R, McGranahan, N, Gulati, S, Gerlinger, M, Birkbak, N J, Joshi, T, Alexandrov, L B, Stratton, M R, Powles, T, Matthews, N, Bates, P A, Stewart, A, Szallasi, Z, Larkin, J, Bartek, J, Swanton, C“…SETD2 (Su(var), Enhancer of zeste, Trithorax-domain containing 2) trimethylates histone-3 lysine-36 (H3K36me3) at sites of active transcription and is mutated in diverse tumour types, including clear cell renal carcinomas (ccRCCs). Distinct SETD2 mutations have been identified in spatially separated regions in ccRCC, indicative of intratumour heterogeneity. …”
Publicado 2015
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146759por Harland, Mark, Petljak, Mia, Robles-Espinoza, Carla Daniela, Ding, Zhihao, Gruis, Nelleke A., van Doorn, Remco, Pooley, Karen A., Dunning, Alison M., Aoude, Lauren G., Wadt, Karin A. W., Gerdes, Anne-Marie, Brown, Kevin M., Hayward, Nicholas K., Newton-Bishop, Julia A., Adams, David J., Bishop, D. Timothy“…One family member had multiple primary melanomas, basal cell carcinomas and a bladder tumour. The blood leukocyte telomere length of a carrier was similar to wild-type cases. …”
Publicado 2015
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146760por Luboldt, Wolfgang, Wiedemann, Baerbel, Fischer, Sebastian, Bodelle, Boris, Luboldt, Hans Joachim, Grünwald, Frank, Vogl, Thomas J.“…METHODS: The SUV(max) was measured in 54 colorectal carcinomas and correlated with gender, age, blood glucose level, injected activity, body mass index and time to scan using t test or correlation coefficients (Pearson or Spearman, according to distribution). …”
Publicado 2016
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