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146761“…BACKGROUND: Atractylenolide I (ATR-1), an active component of Rhizoma Atractylodis Macrocephalae, possesses cytotoxicity against various carcinomas. However, little is known about the effects of ATR-1on bladder cancer. …”
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146762por Tong, Jessica G, Valdes, Yudith Ramos, Barrett, John W, Bell, John C, Stojdl, David, McFadden, Grant, McCart, J Andrea, DiMattia, Gabriel E, Shepherd, Trevor G“…Epithelial ovarian cancer is unique among most carcinomas in that metastasis occurs by direct dissemination of malignant cells traversing throughout the intraperitoneal fluid. …”
Publicado 2015
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146763por Furuya, Mitsuko, Tanaka, Reiko, Okudela, Koji, Nakamura, Satoko, Yoshioka, Hiromu, Tsuzuki, Toyonori, Shibuya, Ryo, Yatera, Kazuhiro, Shirasaki, Hiroki, Sudo, Yoshiko, Kimura, Naoko, Yamada, Kazuaki, Uematsu, Shugo, Kunimura, Toshiaki, Kato, Ikuma, Nakatani, Yukio“…Individuals with BHD have multiple pulmonary cysts and are at a high risk for developing renal cell carcinomas (RCCs). Currently, little information is available about whether pulmonary cysts are absolutely benign or if the lungs are at an increased risk for developing neoplasms. …”
Publicado 2016
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146764por Oga, Emmanuel A., Schumaker, Lisa M., Alabi, Biodun Sulyman, Obaseki, Darlington, Umana, Aniefon, Bassey, Ima-Abasi, Ebughe, Godwin, Oluwole, Olabode, Akeredolu, Teniola, Adebamowo, Sally N., Dakum, Patrick, Cullen, Kevin, Adebamowo, Clement A.“…Histologically, 41% (7/17) of the successfully genotyped blocks were squamous cell carcinomas (larynx 6, maxillary sinus 1). RESULTS AND CONCLUSION: We were unable to detect HPV in any of the HNC samples in our study. …”
Publicado 2016
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146765por Kriegbaum, Mette Camilla, Jacobsen, Benedikte, Füchtbauer, Annette, Hansen, Gert Helge, Christensen, Ib Jarle, Rundsten, Carsten Friis, Persson, Morten, Engelholm, Lars Henning, Madsen, Andreas Nygaard, Di Meo, Ivano, Lund, Ida Katrine, Holst, Birgitte, Kjaer, Andreas, Lærum, Ole Didrik, Füchtbauer, Ernst-Martin, Ploug, Michael“…In chemically induced bladder carcinomas, C4.4A deficiency attenuated the incidence of invasive lesions despite having no effect on total tumour burden. …”
Publicado 2016
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146766por Suzui, Masumi, Futakuchi, Mitsuru, Fukamachi, Katsumi, Numano, Takamasa, Abdelgied, Mohamed, Takahashi, Satoru, Ohnishi, Makoto, Omori, Toyonori, Tsuruoka, Shuji, Hirose, Akihiko, Kanno, Jun, Sakamoto, Yoshimitsu, Alexander, David B., Alexander, William T., Jiegou, Xu, Tsuda, Hiroyuki“…The incidences of malignant mesothelioma and lung tumors (bronchiolo‐alveolar adenomas and carcinomas) were 6/38 and 14/38, respectively, in the three groups administered MWCNT and 0/28 and 0/28, respectively, in the control groups. …”
Publicado 2016
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146767por Boye, Kjetil, Jacob, Havjin, Frikstad, Kari‐Anne M., Nesland, Jahn M., Mælandsmo, Gunhild M., Dahl, Olav, Nesbakken, Arild, Flatmark, Kjersti“…S100A4 expression was analyzed by immunohistochemistry in primary colorectal carcinomas from a consecutively collected, population‐representative cohort and a randomized phase III study on adjuvant 5‐fluorouracil/levamisole. …”
Publicado 2016
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146768por Mohr, Annika, Lüder Ripoli, Florenza, Hammer, Susanne Conradine, Willenbrock, Saskia, Hewicker-Trautwein, Marion, Kiełbowicz, Zdzisław, Murua Escobar, Hugo, Nolte, Ingo“…Among the histological subtypes the lowest gene expression levels of ESR1, PGR and PRLR were found in solid, anaplastic and ductal carcinomas. In summary, the evaluation showed that the measurement of hormone receptors with the multiplex bDNA assay represents a practicable method for obtaining detailed quantitative information about gene expression in canine mammary tissue for future studies. …”
Publicado 2016
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146769por Ross, Jeffrey S., Wang, Kai, Chmielecki, Juliann, Gay, Laurie, Johnson, Adrienne, Chudnovsky, Jacob, Yelensky, Roman, Lipson, Doron, Ali, Siraj M, Elvin, Julia A., Vergilio, Jo‐Anne, Roels, Steven, Miller, Vincent A, Nakamura, Brooke N., Gray, Adam, Wong, Michael K, Stephens, Philip J“…BRAF fusions included 3% (14/531) of melanomas; 2% (15/701) of gliomas; 1.0% (3/294) of thyroid cancers; 0.3% (3/1,062) pancreatic carcinomas; 0.2% (8/4,013) nonsmall‐cell lung cancers and 0.2% (4/2,154) of colorectal cancers, and were enriched in pilocytic (30%) vs. nonpilocytic gliomas (1%; p < 0.0001), Spitzoid (75%) vs. nonSpitzoid melanomas (1%; p = 0.0001), acinar (67%) vs. nonacinar pancreatic cancers (<1%; p < 0.0001) and papillary (3%) vs. nonpapillary thyroid cancers (0%; p < 0.03). …”
Publicado 2016
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146770“…Our data provides rationale for potential combinations of erlotinib and immunotherapies for the treatment of lung carcinomas in the early setting, before the establishment of tumor relapse with long-term EGFR inhibition.…”
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146771por Meng, Jie, Zhu, Lijing, Zhu, Li, Wang, Huanhuan, Liu, Song, Yan, Jing, Liu, Baorui, Guan, Yue, Ge, Yun, He, Jian, Zhou, Zhengyang, Yang, Xiaofeng“…Thirty-two patients with advanced cervical squamous cell carcinomas underwent diffusion weighted magnetic resonance imaging (b values, 0 and 800 s/mm(2)) before CCRT, at the end of 2nd and 4th week during CCRT and immediately after CCRT completion. …”
Publicado 2016
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146772por Lin, Min-Qiang, Li, Yue-Ping, Wu, San-Gang, Sun, Jia-Yuan, Lin, Huan-Xin, Zhang, Shi-Yang, He, Zhen-Yu“…Compared with Caucasian patients, the Chinese patients had a later year of diagnosis, remained married after EC was diagnosed, had esophageal squamous cell carcinomas (ESCCs) more frequently, had tumors located in the upper-third and middle-third of the esophagus more frequently, and fewer patients presented with poorly/undifferentiated EC and underwent cancer-directed surgery. …”
Publicado 2016
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146773por Sbardella, Emilia, Farah, George, Fathelrahman, Ahmed, Cudlip, Simon, Ansorge, Olaf, Karavitaki, Niki, Grossman, Ashley B“…They can be classified according to pathological, radiological or clinical behaviour as typical, atypical or carcinomas, invasive or noninvasive, and aggressive or nonaggressive. …”
Publicado 2016
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146774por Park, Hyung Chul, Kim, Do Hoon, Gong, Eun Jeong, Na, Hee Kyong, Ahn, Ji Yong, Lee, Jeong Hoon, Jung, Kee Wook, Choi, Kee Don, Song, Ho June, Lee, Gin Hyug, Jung, Hwoon-Yong, Kim, Jin-Ho“…RESULTS: ESD was performed in 225 patients with 261 lesions, including 70 cases (26.8%) of dysplasias and 191 cases (73.2%) of squamous cell carcinomas. The median age was 65 years (range, 44 to 86), and the male to female ratio was 21.5:1. …”
Publicado 2016
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146775por Gao, Li, Wu, Wei-Feng, Dong, Lei, Ren, Gui-Ling, Li, Hai-Di, Yang, Qin, Li, Xiao-Feng, Xu, Tao, Li, Zeng, Wu, Bao-Ming, Ma, Tao-Tao, Huang, Cheng, Huang, Yan, Zhang, Lei, Lv, Xiongwen, Li, Jun, Meng, Xiao-Ming“…Cisplatin is a classic chemotherapeutic agent widely used to treat different types of cancers including ovarian, head and neck, testicular and uterine cervical carcinomas. However, cisplatin induces acute kidney injury by directly triggering an excessive inflammatory response, oxidative stress, and programmed cell death of renal tubular epithelial cells, all of which lead to high mortality rates in patients. …”
Publicado 2016
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146776por Yokoyama, Seiya, Higashi, Michiyo, Kitamoto, Sho, Oeldorf, Monika, Knippschild, Uwe, Kornmann, Marko, Maemura, Kosei, Kurahara, Hiroshi, Wiest, Edwin, Hamada, Tomofumi, Kitazono, Ikumi, Goto, Yuko, Tasaki, Takashi, Hiraki, Tsubasa, Hatanaka, Kazuhito, Mataki, Yuko, Taguchi, Hiroki, Hashimoto, Shinichi, Batra, Surinder K., Tanimoto, Akihide, Yonezawa, Suguru, Hollingsworth, Michael A.“…These are overexpressed in many carcinomas, and high expression of these molecules is a risk factor associated with poor prognosis. …”
Publicado 2016
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146777por Carton, Matthieu, Barul, Christine, Menvielle, Gwenn, Cyr, Diane, Sanchez, Marie, Pilorget, Corinne, Trétarre, Brigitte, Stücker, Isabelle, Luce, Danièle“…METHODS: Investigation of occupational and environmental CAuses of REspiratory cancers (ICARE), a French population-based case–control study, included 296 squamous cell carcinomas of the head and neck (HNSCC) in women and 775 female controls. …”
Publicado 2017
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146778“…Risk factors for esophageal carcinomas include obesity, gastroesophageal reflux disease, hard-alcohol use and tobacco smoking. …”
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146779por Darvin, Pramod, Joung, Youn Hee, Kang, Dong Young, Sp, Nipin, Byun, Hyo Joo, Hwang, Tae Sook, Sasidharakurup, Hema, Lee, Chi Ho, Cho, Kwang Hyun, Park, Kyung Do, Lee, Hak Kyo, Yang, Young Mok“…Taken together, our results suggest that TA modulates EGF‐R/Jak2/STAT1/3 and P38/STAT1/p21(Waf1/Cip1) pathways and induce G1‐arrest and intrinsic apoptosis in breast carcinomas.…”
Publicado 2016
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146780por Riveiro, Maria E., Astorgues-Xerri, Lucile, Vazquez, Ramiro, Frapolli, Roberta, Kwee, Ivo, Rinaldi, Andrea, Odore, Elodie, Rezai, Keyvan, Bekradda, Mohamed, Inghirami, Giorgio, D'Incalci, Maurizio, Noel, Kay, Cvitkovic, Esteban, Raymond, Eric, Bertoni, Francesco“…Inhibitors targeting epigenetic control points of oncogenes offer a potential mean of blocking tumor progression in small cell and non-small cell lung carcinomas (SCLC, NSCLC). OTX015 (MK-8628) is a BET inhibitor selectively blocking BRD2/3/4. …”
Publicado 2016
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