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146841por Harris, Kelly L., Walia, Vijay, Gong, Binsheng, McKim, Karen L., Myers, Meagan B., Xu, Joshua, Parsons, Barbara L.“…CarcSeq was used for mutational analysis of 13 amplicons encompassing >20 hotspot CDMs in normal breast, normal lung, ductal carcinomas, and lung adenocarcinomas. The approach was validated by detecting expected differences related to tissue type (normal vs. tumor and breast vs. lung) and mutation spectra. …”
Publicado 2020
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146842por Orlandi, Armando, Iattoni, Elena, Pizzuti, Laura, Fabbri, Agnese, Botticelli, Andrea, Di Dio, Carmela, Palazzo, Antonella, Garufi, Giovanna, Indellicati, Giulia, Alesini, Daniele, Carbognin, Luisa, Paris, Ida, Vaccaro, Angela, Moscetti, Luca, Fabi, Alessandra, Magri, Valentina, Naso, Giuseppe, Cassano, Alessandra, Vici, Patrizia, Giannarelli, Diana, Franceschini, Gianluca, Marchetti, Paolo, Bria, Emilio, Tortora, Giampaolo“…It is not clear if patients with lobular breast carcinomas (LBC) derive the same benefits when receiving second line CDK4/6i. …”
Publicado 2020
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146843“…BACKGROUND: Previous studies have suggested that long non-coding RNAs (lncRNAs) were involved in tumorigenesis of various human carcinomas, including osteosarcoma (OS). However, the expression and specific role of lncRNA HLA complex group 11 (HCG11) in OS remain unknown. …”
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146844por Kilvaer, Thomas K, Paulsen, Erna-Elise, Andersen, Sigve, Rakaee, Mehrdad, Bremnes, Roy M, Busund, Lill-Tove Rasmussen, Donnem, Tom“…The prognostic efficacy of the CD8(+) TIL density is strongest in lung squamous cell carcinomas, whereas both CD8(+) TILs and CD20(+) TILs, or a combination of these, may be candidates for a TNM-I in lung adenocarcinoma. …”
Publicado 2020
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146845por Funaki, Soichiro, Shintani, Yasushi, Fukui, Eriko, Kanzaki, Ryu, Kanou, Takashi, Ose, Naoko, Minami, Masato, Okumura, Meinoshin“…As a result, clinical data regarding thymomas have not been well discussed as compared to those of other carcinomas. Also, because of the low morbidity rate and insufficient clinical experience, oncological characteristics and clinical treatment options are poorly understood. …”
Publicado 2020
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146846por Rodriguez‐Pinilla, Socorro Maria, Domingo‐Domenech, Eva, Climent, Fina, Sanchez, Joaquin, Perez Seoane, Carlos, Lopez Jimenez, Javier, Garcia‐Cosio, Monica, Caballero, Dolores, Blanco Muñez, Oscar Javier, Carpio, Cecilia, Castellvi, Josep, Martinez Pozo, Antonio, Gonzalez Farre, Blanca, Bendaña, Angeles, Aliste, Carlos, Gonzalez, Ana Julia, Gonzalez de Villambrosia, Sonia, Piris, Miguel A., Gomez Codina, Jose, Mayordomo‐Aranda, Empar, Navarro, Belen, Bellas, Carmen, Rodriguez, Guillermo, Borrero, Juan Jose, Ruiz‐Zorrilla, Ana, Grande, Marta, Montoto, Carmen, Cordoba, Raul“…A sizeable proportion of 175 patients had a history of immune‐related disorders (autoimmune 16%, viral infections 17%, chemo/radiotherapy‐treated carcinomas 19%). The median progression‐free survival (PFS) and overall survival (OS) were 7·9 and 15·8 months, respectively. …”
Publicado 2020
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146847Primary thymus tumors: retrospective case analysis at a reference center in Latin America, 2011–2019por Scarpetta-Gonzalez, Diego F., Morales, Eliana Isabel, Sua, Luz Fernanda, Velásquez, Mauricio, Sangiovanni, Saveria, Fernández-Trujillo, Liliana“…RESULTS: 18 patients with thymic tumors were included, of which specific histologic studies reveled thymomas, carcinomas, neuroendocrine tumors, thymolipoma and thymic cyst. …”
Publicado 2021
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146848por Tanaka, Shinji, Saitoh, Yusuke, Matsuda, Takahisa, Igarashi, Masahiro, Matsumoto, Takayuki, Iwao, Yasushi, Suzuki, Yasumoto, Nozaki, Ryoichi, Sugai, Tamotsu, Oka, Shiro, Itabashi, Michio, Sugihara, Ken-ichi, Tsuruta, Osamu, Hirata, Ichiro, Nishida, Hiroshi, Miwa, Hiroto, Enomoto, Nobuyuki, Shimosegawa, Tooru, Koike, Kazuhiko“…RESULTS: The professional committee created 18 CQs and statements concerning the current concept and diagnosis/treatment of various colorectal polyps, including their epidemiology, screening, pathophysiology, definition and classification, diagnosis, management, practical treatment, complications, and surveillance after treatment, and other colorectal lesions (submucosal tumors, nonneoplastic polyps, polyposis, hereditary tumors, ulcerative colitis-associated tumors/carcinomas). CONCLUSIONS: After evaluation by the moderators, evidence-based clinical practice guidelines for management of colorectal polyps were proposed for 2020. …”
Publicado 2021
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146849por Halle, Mari K., Sødal, Marte, Forsse, David, Engerud, Hilde, Woie, Kathrine, Lura, Njål G., Wagner-Larsen, Kari S., Trovik, Jone, Bertelsen, Bjørn I., Haldorsen, Ingfrid S., Ojesina, Akinyemi I., Krakstad, Camilla“…We investigated transcriptional data from cervical carcinomas related to patient survival and recurrence to identify potential molecular drivers for aggressive disease. …”
Publicado 2021
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146850“…We propose that molecular changes in the expression of plakins leads to the transition of benign ovarian tumours to carcinomas, as well as floating cellular aggregates (commonly known as spheroids) in the ascites microenvironment, which may contribute to the sustenance and progression of the disease. …”
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146851por Tanaka, Hiroyuki, Kawashima, Hiroki, Ohno, Eizaburo, Ishikawa, Takuya, Iida, Tadashi, Ishikawa, Eri, Furukawa, Kazuhiro, Nakamura, Masanao, Honda, Takashi, Shimoyama, Yoshie, Miyahara, Ryoji, Kawabe, Naoto, Kuzuya, Teiji, Hashimoto, Senju, Ishigami, Masatoshi, Hirooka, Yoshiki, Fujishiro, Mitsuhiro“…Insulin-like growth factor 2 mRNA protein 3 (IMP3) staining is reportedly associated with advanced disease stage and clinical outcomes in many carcinomas. The aim of this retrospective study was to investigate the ability of diagnosing sphincter of Oddi involvement in PT and predicting the prognoses using IMP3 immunohistochemistry. …”
Publicado 2021
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146852por Horváth, Angéla, Prekopp, Péter, Polony, Gábor, Székely, Eszter, Tamás, László, Dános, Kornél“…PURPOSE: The presence of cervical lymph node metastases is one of the most influential prognostic factors in head and neck squamous cell carcinomas. The management of clinically N0 neck in patients with head and neck cancer remains controversial: elective neck dissection has relatively high morbidity, adversely affecting the quality of life, however, abandoning elective neck dissection is known to compromise overall survival in numerous primaries. …”
Publicado 2020
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146853por Rakha, Emad A., Miligy, Islam M., Quinn, Cecily M., Provenzano, Elena, Shaaban, Abeer M., Marchiò, Caterina, Toss, Michael S., Gallagy, Grace, Murray, Ciara, Walshe, Janice, Katayama, Ayaka, Eldib, Karim, Badr, Nahla, Tanchel, Bruce, Millican-Slater, Rebecca, Purdie, Colin, Purnell, Dave, Pinder, Sarah E., Ellis, Ian O., Lee, Andrew H. S.“…Our data suggest that ASCO/CAP HER2 Group 2 carcinomas should be evaluated further with respect to eligibility for HER2 targeted therapy.…”
Publicado 2021
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146854por Lin, Xiaofeng, Zhou, Shoujun, Wen, Tiexiang, Jiang, Shenghao, Wang, Cheng, Chen, Jingtao“…PURPOSE: Radioactive seed implantation is an effective invasive treatment method for malignant liver tumors in hepatocellular carcinomas. However, challenges of the manual procedure may degrade the efficacy of the technique, such as the high accuracy requirement and radiation exposure to the surgeons. …”
Publicado 2021
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146855por Guimarães, Giuliana Gismonti, Perez, Danyel Elias da Cruz, Netto, Juliana de Noronha Santos, da Costa, Ana Camily Oliveira, Leonel, Augusto César Leal da Silva, de Castro, Jurema Freire Lisboa, Pires, Fábio Ramoa“…Malignant nonendodontic periapical lesions (8 cases, 1%) included carcinomas, adenocarcinomas, and melanoma. In general, nonendodontic periapical lesions were more common in males and in the posterior mandible (p>0.05). …”
Publicado 2021
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146856por Stratmann, Katharina, Czerwinska, Katarzyna, Filmann, Natalie, Tacke, Wolfgang, Weber, Christoph, Bock, Herbert, Blumenstein, Irina“…In total, six colorectal carcinomas (0.4%) were detected. There were no significant differences between men and women. …”
Publicado 2021
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146857por Li, Li-Yan, Yang, Qian, Jiang, Yan-Yi, Yang, Wei, Jiang, Yuan, Li, Xiang, Hazawa, Masaharu, Zhou, Bo, Huang, Guo-Wei, Xu, Xiu-E, Gery, Sigal, Zhang, Ying, Ding, Ling-Wen, Ho, Allen S., Zumsteg, Zachary S., Wang, Ming-Rong, Fullwood, Melissa J., Freedland, Stephen J., Meltzer, Stephen J., Xu, Li-Yan, Li, En-Min, Koeffler, H. Phillip, Lin, De-Chen“…Squamous cell carcinomas (SCCs) comprise one of the most common histologic types of human cancer. …”
Publicado 2021
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146858“…A total of 47,180 pituitary tumors were identified, including 47,030 typical adenomas, 111 uncertain behavior pituitary adenomas, and 39 pituitary carcinomas. The overall standardized incidence rate was 4.8 cases per 100,000 person-years and the annual incidence rate continually trended upwards, with a peak seen in 2015. …”
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146859por Haritha, Nair Hariprasad, Nawab, Akbar, Vijayakurup, Vinod, Anto, Nikhil Ponnoor, Liju, Vijayasteltar B., Alex, Vijai V., Amrutha, Areekkara Nisthul, Aiswarya, Sreekumar U., Swetha, Mundanattu, Vinod, Balachandran S., Sundaram, Sankar, Guijarro, Maria V., Herlevich, Thomas, Krishna, Archana, Nestory, Nesteena K., Bava, Smitha V., Sadasivan, Chittalakkottu, Zajac-Kaye, Maria, Anto, Ruby John“…CONCLUSION: This is the first-ever pre-clinical study portraying TS as the critical target of combinatorial therapy for mammary carcinomas and therefore we recommend its clinical validation, especially in TNBC patients, who currently have limited therapeutic options.…”
Publicado 2021
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146860“…Tumor-infiltrating CD1a(+) DCs have been reported to be associated with clinical outcomes in carcinomas of various organs, but the clinical impact of CD1a(+) DCs in laryngeal cancer remains to be unequivocally established. …”
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