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147401por Assidi, Mourad“…N-CAD protein has also been shown to be overexpressed in many advanced carcinomas. The aim of this study was to investigate the expression patterns of N-CAD protein, determine their correlations with the clinicopathological features of OC patients, and evaluate its prognostic value and involvement in EMT and metastasis. …”
Publicado 2022
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147402por Mansour, Mohammed S. I., Malmros, Karina, Mager, Ulrich, Ericson Lindquist, Kajsa, Hejny, Kim, Holmgren, Benjamin, Seidal, Tomas, Dejmek, Annika, Dobra, Katalin, Planck, Maria, Brunnström, Hans“…Adenocarcinomas exhibited lower PD-L1 expression than squamous cell carcinomas (p < 0.0001), while there was no difference between sample types, tumor locations, or between the two cohorts in multivariate analysis (all p ≥ 0.28). …”
Publicado 2022
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147403por Peltanová, Barbora, Holcová Polanská, Hana, Raudenská, Martina, Balvan, Jan, Navrátil, Jiří, Vičar, Tomáš, Gumulec, Jaromír, Čechová, Barbora, Kräter, Martin, Guck, Jochen, Kalfeřt, David, Grega, Marek, Plzák, Jan, Betka, Jan, Masařík, Michal“…ABSTRACT: Head and neck squamous cell carcinomas (HNSCC) belong among severe and highly complex malignant diseases showing a high level of heterogeneity and consequently also a variance in therapeutic response, regardless of clinical stage. …”
Publicado 2022
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147404por Topcu, Ramazan, Şahiner, İbrahim T., Kendirci, Murat, Erkent, Murathan, Sezikli, İsmail, Tutan, Mehmet B.“…OBJECTIVES: To investigate the influence of the metastatic lymph node/total lymph node ratio (N-ratio) on survival and prognosis in surgically treated gastric carcinomas. METHODS: A retrospective review of 73 patients who underwent curative resection at the Department of General Surgery, Hitit University Faculty of Medicine, Turkey. …”
Publicado 2022
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147405por Rano, Elodie, Lin, Lucien, Molinie, Vincent, Sulpicy, Caroline, Dorival, Marie-Josée, Drak Alsibai, Kinan, Nacher, Mathieu, Drame, Moustafa, Sabbah, Nadia“…The final histological examination revealed papillary microcarcinomas in 61% of cases and papillary carcinomas in 39% of cases. Thyroid cytology alone had a low sensitivity (22.2%) and positive predictive value (15.4%) for the diagnosis of malignancy, with a good specificity (91.1%) and negative predictive value (94.2%). …”
Publicado 2022
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147406“…Our results show how the distribution of E-cadherin adhesions, supported by actin density and architecture, is modulated by epithelial cell-like elasticity and have significant implications for disease states like carcinomas characterized by altered epithelial cell elasticity.…”
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147407por Boguszewicz, Łukasz“…This review focuses on the molecular biology of head and neck squamous cell carcinomas and presents current and emerging biomarkers of the response of patients to induction chemotherapy. …”
Publicado 2022
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147408por Guo, Wenjing, Gao, Huabin, Li, Hui, Ge, Songhan, Zhang, Fenfen, Wang, Liyuan, Shi, Huijuan, Han, Anjia“…[Image: see text] Compared with the traditional single therapy, nanomedicine has promoted a multimodal combination treatment for various carcinomas, especially the development of corresponding intelligent multifunctional biomaterials based on advanced DNA nanotechnology has great potential in cancer combination therapy. …”
Publicado 2022
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147409por Brown, Benjamin P., Zhang, Yun-Kai, Kim, Soyeon, Finneran, Patrick, Yan, Yingjun, Du, Zhenfang, Kim, Jiyoon, Hartzler, Abigail Leigh, LeNoue-Newton, Michele L., Smith, Adam W., Meiler, Jens, Lovly, Christine M.“…Oncogenic mutations within the epidermal growth factor receptor (EGFR) are found in 15 to 30% of all non–small-cell lung carcinomas. The term exon 19 deletion (ex19del) is collectively used to refer to more than 20 distinct genomic alterations within exon 19 that comprise the most common EGFR mutation subtype in lung cancer. …”
Publicado 2022
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147410“…Despite the notable clinical success of mTOR inhibitors in extending the overall survival of patients with certain malignancies including metastatic renal cell carcinomas (RCCs), the overall impact of mTOR inhibitors on cancers has been generally disappointing and attributed to various compensatory responses. …”
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147411por Cappelli, Katia, Ciucis, Chiara Grazia De, Mecocci, Samanta, Nervo, Tiziana, Crescio, Maria Ines, Pepe, Marco, Gialletti, Rodolfo, Pietrucci, Daniele, Migone, Laura Federica, Turco, Silvia, Mechelli, Luca, Passamonti, Fabrizio, Drago, Carlo, Donato, Gian Guido, Varello, Katia, Modesto, Paola, Chillemi, Giovanni, Ghelardi, Alessandro, Razzuoli, Elisabetta“…Equine Papillomavirus 2 (EcPV2) is responsible for squamous cell carcinomas (eSCCs) of external genitalia of both male and female horses. …”
Publicado 2022
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147412por Zhu, Dimin, Wang, Zongming, Tian, Tian, Wu, Xinyi, He, Dongsheng, Zhu, Yonghong, Liu, Dawei, Wang, Haijun“…The tumor recurrence rate was as high as 55.6%, with 6 cases progressing to pituitary carcinomas and 7.7% of tumor-related deaths. Our further integrated analysis of our center and reported cases revealed that gender, Cushing’s syndrome, visual dysfunction, hormonal disorders, and tumor growth characteristics were statistically different in different tumor categories. …”
Publicado 2022
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147413por Hofmann, Linda, Abou Kors, Tsima, Ezić, Jasmin, Niesler, Beate, Röth, Ralph, Ludwig, Sonja, Laban, Simon, Schuler, Patrick J., Hoffmann, Thomas K., Brunner, Cornelia, Medyany, Valentin, Theodoraki, Marie-Nicole“…Background: Head and neck squamous cell carcinomas (HNSCC) lack tumor-specific biomarkers. Exosomes from HNSCC patients carry immunomodulatory molecules, and correlate with clinical parameters. …”
Publicado 2022
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147414por Toraih, Eman A., Fawzy, Manal S., Ning, Bo, Zerfaoui, Mourad, Errami, Youssef, Ruiz, Emmanuelle M., Hussein, Mohammad H., Haidari, Muhib, Bratton, Melyssa, Tortelote, Giovane G., Hilliard, Sylvia, Nilubol, Naris, Russell, Jonathon O., Shama, Mohamed A., El-Dahr, Samir S., Moroz, Krzysztof, Hu, Tony, Kandil, Emad“…ABSTRACT: Papillary thyroid carcinomas (PTCs) account for most endocrine tumors; however, screening and diagnosing the recurrence of PTC remains a clinical challenge. …”
Publicado 2022
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147415“…RESULTS: Clinical measurement results for 99 skin pathologies, including basal cell carcinomas, melanoma, dermal nevi, combined nevi, junctional nevi, blue nevi, seborrheic keratosis, and hemangiomas. …”
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147416por Sharma, Rashim, Elhence, Poonam Abhay, Rao, Meenakshi, Khera, Sudeep, Vedant, Deepak, Chaudhary, Ramkaran, Pareek, Puneet, Vishnoi, Jeewan Ram, Misra, Sanjeev“…The present study aimed to assess Programmed Death Ligand-1 (PD-L1) expression in tumoral cells and tumor-infiltrating lymphocytes (TILs) and evaluate their correlations with the Ki-67 labelling index in invasive breast carcinomas (IBC). METHODS: This descriptive observational study was conducted during 2016-2018 and included all diagnosed cases of IBC. …”
Publicado 2022
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147417por Cometi, Laura, Bruni, Cosimo, Passavanti, Saverio, Tofani, Lorenzo, Bartoli, Francesca, Fiori, Ginevra, Nacci, Francesca, Lepri, Gemma, Orlandi, Martina, Melchiorre, Daniela, Antonuzzo, Lorenzo, Matucci-Cerinic, Marco, Moggi-Pignone, Alberto“…The most common malignancies that we found were lung cancers, ductal mammary carcinomas, melanomas, and lymphomas. The incidence rate (IR) of malignancies in our cohort was 3.47 per 1000 person-years (p-y); the higher IRs were in RA patients (5.13 per 1000 p-y), in males (4.21 per 1000 p-y), and in patients aged >70 years (10.14 per 1000 p-y). …”
Publicado 2020
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147418por Kuempers, Christiane, Jagomast, Tobias, Heidel, Carsten, Paulsen, Finn-Ole, Bohnet, Sabine, Schierholz, Stefanie, Dreyer, Eva, Kirfel, Jutta, Perner, Sven“…In this study, we aimed to investigate the protein expression of CDK7 in a large cohort of NSCLC incorporating adenocarcinomas (adNSCLC) and squamous cell carcinomas (sqNSCLC) and to correlate its expression with clinicopathological data. …”
Publicado 2022
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147419por Barba‐Montero, Catalina, Lorenzo‐Pouso, Alejandro Ismael, Gándara‐Vila, Pilar, Blanco‐Carrión, Andrés, Marichalar‐Mendía, Xabier, García‐García, Abel, Pérez‐Sayáns, Mario“…Eleven patients (32.4%) were affected by oral cancer during the follow‐up, developing a total of 15 carcinomas. The mean age of malignant transformation was 67.2 ± 12.9 years, particularly 8 ± 8.5 from the onset of the lesions. …”
Publicado 2022
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147420“…METHODS: Sixty‐nine HCP cases with surgical follow‐up were identified, including 35 NN, 20 adenomas, and 14 carcinomas. Ultrasound data were recorded utilizing Thyroid Imaging Reporting and Data System (TI‐RADS) and American Thyroid Association (ATA) scoring systems. …”
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