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147681por Xu, Song, Li, Xiongfei, Zhang, Hongyi, Zu, Lingling, Yang, Lingqi, Shi, Tao, Zhu, Shuai, Lei, Xi, Song, Zuoqing, Chen, Jun“…PURPOSE: Thymic epithelial tumors (TETs) are relatively rare neoplasms, including thymomas (types A, AB, B1, B2, and B3) and thymic carcinomas (TCs). The current knowledge about the biological properties of TETs is limited due to their low incidence. …”
Publicado 2021
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147682“…Compared to typical gastrointestinal carcinomas, GISTs exhibit unique malignant behaviors. …”
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147683por Wang, Shuangshuang, Qian, Hua, Zhang, Liwei, Liu, Panpan, Zhuang, Dexuan, Zhang, Qun, Bai, Fuxiang, Wang, Zhihong, Yan, Yonggan, Guo, Jing, Huang, Jun, Wu, Xunwei“…Mutations of H-Ras, a member of the RAS family, are preferentially found in cutaneous squamous cell carcinomas (SCCs). H-Ras has been reported to induce autophagy, which plays an essential role in tissue homeostasis in multiple types of cancer cells and in fibroblasts, however, the potential role of H-Ras in regulating autophagy in human keratinocytes has not been reported. …”
Publicado 2021
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147684por Martin, Benedikt, Greinacher, Andreas, Bülow, Robin, Hammer, Fabian, Hoene, Andreas, Burchardt, Martin, Zimmermann, Uwe“…Paraneoplastic syndromes (PNS) represent a frequent complication of renal cell carcinomas (RCC) and include different hematological symptoms in patients, whilst occlusion of arterial blood vessels displays a rare form of PNS accompanying renal tumors. …”
Publicado 2021
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147685“…None of the CHF-i patients had kidney disease, but 3 were associated with hepatic carcinomas. Histology analysis demonstrated characteristic triads (bile duct abnormalities, portal vein hypoplasia, and fibrosis) in all CHF cases. …”
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147686por Robbins, Yvette, Friedman, Jay, Clavijo, Paul E, Sievers, Cem, Bai, Ke, Donahue, Renee N, Schlom, Jeffrey, Sinkoe, Andrew, Abdul Sater, Houssein, Gulley, James L, Norberg, Scott, Hinrichs, Christian S, Allen, Clint“…Genomic alterations in TGF-b superfamily genes were infrequent in papillomas and normal mucosa but present in a significant fraction of head and neck carcinomas. CONCLUSIONS: Intact TGF-b signaling restrains proliferation within papillomas, and the use of clinical agents that abrogate this pathway should be avoided in patients with RRP. …”
Publicado 2021
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147687por Blundo, Concetta, Giroda, Massimo, Fusco, Nicola, Sajjadi, Elham, Venetis, Konstantinos, Leonardi, M. Cristina, Vicini, Elisa, Despini, Luca, Rossi, Claudia F., Runza, Letterio, Sfondrini, Maria S., Piciotti, Roberto, Di Loreto, Eugenia, Scarfone, Giovanna, Guerini-Rocco, Elena, Viale, Giuseppe, Veronesi, Paolo, Buonomo, Barbara, Peccatori, Fedro A., Galimberti, Viviana E.“…Among the study group, 4 (12.3%) patients experienced ILR or new carcinomas after 6-13 years, the same number (n=4) had metastatic dissemination after 3-7 years. …”
Publicado 2021
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147688por Li, Binghao, Qu, Hao, Zhang, Jing, Pan, Weibo, Liu, Meng, Yan, Xiaobo, Huang, Xin, He, Xuexin, Lin, Dong, Liu, Sisi, Guan, Ruting, Wu, Yong, Ou, Qiuxiang, Bao, Hua, Xu, Youbin, Wu, Xue, Shao, Yang, Lin, Nong“…A total of 1162 patients (6.66%; 1162/17,442) were identified as having kinase fusions, including 906 adenocarcinomas (ADCs) and 35 squamous cell carcinomas (SCCs). In ADC, 170 unique gene fusion pairs were observed, including rare kinase fusions, SLC12A2-ROS1, NCOA4-RET, and ANK3-RET. …”
Publicado 2021
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147689por Savall, Mathilde, Senni, Nadia, Lagoutte, Isabelle, Sohier, Pierre, Dentin, Renaud, Romagnolo, Beatrice, Perret, Christine, Bossard, Pascale“…CTNNB1 (catenin beta 1)–mutated hepatocellular carcinomas (HCCs) account for a large proportion of human HCCs. …”
Publicado 2021
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147690por Rubio, Teresa, Weyershaeuser, Judith, Montero, Marta G., Hoffmann, Andreas, Lujan, Pablo, Jechlinger, Martin, Sotillo, Rocio, Köhn, Maja“…Expression of the phosphatase of regenerating liver-3 (PRL-3) is known to promote tumor growth in gastrointestinal adenocarcinomas, and the incidence of tumor formation upon inflammatory events correlates with PRL-3 levels in mouse models. These carcinomas and their onset are associated with the impairment of intestinal cell homeostasis, which is regulated by a balanced number of Paneth cells and Lgr5 expressing intestinal stem cells (Lgr5+ ISCs). …”
Publicado 2021
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147691por Lin, Selena Y., Su, Yih‐Ping, Trauger, Evan R., Song, Benjamin P., Thompson, Emilie G.C., Hoffman, Malcolm C., Chang, Ting‐Tsung, Lin, Yih‐Jyh, Kao, Yu‐Lan, Cui, Yixiao, Hann, Hie‐Won, Park, Grace, Shieh, Fwu‐Shan, Song, Wei, Su, Ying‐Hsiu“…Integrated hepatitis B virus (HBV) DNA, found in more than 85% of HBV‐associated hepatocellular carcinomas (HBV‐HCCs), can play a significant role in HBV‐related liver disease progression. …”
Publicado 2021
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147692por Popa, Oana, Tăban, Sorina Maria, Dema, Alis Liliana Carmen, Plopeanu, Andrei Dorel, Barna, Robert Alexandru, Cornianu, Mărioara, Dema, Sorin“…A significant relationship was observed between the CXCR4 expression and the tumor grade (p=0.0216), and high IRS value was correlated with clinical stages III and IV (p=0.0142) and lympho-vascular invasion (p=0.0129). 74.1% of G1 neuroendocrine tumors (NETs) had a low IRS, G3 NETs showed minor differences between low (42.9%) and high (57.1%) expression and 66.7% of neuroendocrine carcinomas (NECs) presented high expression of CXCR4. …”
Publicado 2021
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147693por Lin, Xinqing, Peng, Muyun, Chen, Quanfang, Yuan, Mingming, Chen, Rongrong, Deng, Haiyi, Deng, Jiaxi, Liu, Ouqi, Weng, Yuqing, Chen, Mingjiu, Zhou, Chengzhi“…Five patients were diagnosed as multiple primary carcinomas. Family history was documented in 31.3% (20/64) of patients, 55% of which were diagnosed as lung cancer. …”
Publicado 2021
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147694por Greenland, Nancy Y., Cooperberg, Matthew R., Wong, Anthony C., Chan, Emily, Carroll, Peter R., Simko, Jeffry P., Stohr, Bradley A.“…CONCLUSIONS: Among Gleason 3+4=7 carcinomas, large cribriform was associated with higher Decipher scores and greater BCR risk. …”
Publicado 2022
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147695“…BACKGROUND: LncRNA POU3F3 (POU3F3) is overexpressed and plays oncogenic roles in esophageal squamous-cell carcinomas. LncRNA MEG3 (MEG3) has been characterized as a tumor suppressive lncRNA in different types of cancer. …”
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147696por Wedekind, Hanna, Walz, Kristina, Buchbender, Mayte, Rieckmann, Thorsten, Strasser, Erwin, Grottker, Fridolin, Fietkau, Rainer, Frey, Benjamin, Gaipl, Udo S, Rückert, Michael“…PURPOSE: The incidence of head and neck squamous cell carcinomas (HNSCC) is increasing worldwide, especially when triggered by the human papilloma virus (HPV). …”
Publicado 2021
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147697por Vitali, Francesco, Wein, Axel, Rath, Timo, Eckstein, Markus, Neufert, Clemens, Siebler, Jürgen, Atreya, Raja, Hartmann, Arndt, Hohenberger, Werner, Weber, Klaus, Neurath, Markus Friedrich, Grützmann, Robert, Merkel, Susanne“…CONCLUSION: IBD-CRC patients were younger and more frequently had right-sided carcinomas compared to sporadic CRC. CRC in IBD patients did not show survival difference compared to matched-pair sporadic CRC patients without distant metastases after curative resection. …”
Publicado 2021
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147698por Alva-Ruiz, Roberto, Yohanathan, Lavanya, Yonkus, Jennifer A., Abdelrahman, Amro M., Gregory, Lindsey A., Halfdanarson, Thorvadur R., Mahipal, Amit, McWilliams, Robert R., Ma, Wen Wee, Hallemeier, Christopher L., Graham, Rondell P., Grotz, Travis E., Smoot, Rory L., Cleary, Sean P., Nagorney, David M., Kendrick, Michael L., Truty, Mark J.“…Variant histologic exocrine carcinomas, intraductal papillary mucinous neoplasm-associated PDAC, and patients without research consent were excluded. …”
Publicado 2021
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147699“…P53 and DNA damage‐regulated gene1 (PDRG1) is overexpressed in diverse carcinomas. Here, we discover that PDRG1 is overexpressed in glioblastoma multiforme (GBM). …”
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147700por Cai, Shang, Ma, Jiayan, Wang, Yong, Cai, Yuxing, Xie, Liwei, Chen, Xiangying, Yang, Yingying, Peng, Qiliang“…BACKGROUND: MicroRNA (miRNA) has been reported to play a critical regulatory role in papillary thyroid carcinomas (PTC). However, the role of miR-221/222 in PTC remains unclear. …”
Publicado 2022
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