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147941por Hubackova, Sona, Pribyl, Miroslav, Kyjacova, Lenka, Moudra, Alena, Dzijak, Rastislav, Salovska, Barbora, Strnad, Hynek, Tambor, Vojtech, Imrichova, Terezie, Svec, Jiri, Vodicka, Pavel, Vaclavikova, Radka, Rob, Lukas, Bartek, Jiri, Hodny, Zdenek“…Importantly, SBSN expression was observed in human clinical specimens of colon and ovarian carcinomas, as well as in circulating tumour cells and metastases of the 4T1 mouse model. …”
Publicado 2019
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147942por Wei, Siliang, Zheng, Yuanyuan, Jiang, Yanru, Li, Xiaojun, Geng, Jian, Shen, Yuanbing, Li, Qin, Wang, Xiaojing, Zhao, Chengling, Chen, Yuqing, Qian, Zhongqing, Zhou, Jihong, Li, Wei“…BACKGROUND: Non-small cell lung carcinomas (NSCLC) are prevalent, lethal cancers with especially grim prospects due to late-stage detection and chemoresistance. …”
Publicado 2019
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147943por Yu, Yong-Bo, Wang, Yong-Hua, Yang, Xue-Cheng, Zhao, Yang, Wang, Mei-Lan, Liang, Ye, Niu, Hai-Tao“…The virus was relevantly associated with basaloid (85.5%, 95% CI: 77.2%–93.8%) and warty (50.0%, 95% CI: 35.2%–64.8%) carcinomas. The invasiveness of PeCa was not associated with HPV (χ(2) = 0.181, df = 1, P < 0.671). …”
Publicado 2019
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147944por Povsic, Manca, Enstone, Ashley, Wyn, Robin, Kornalska, Klaudia, Penrod, John R., Yuan, Yong“…OBJECTIVES: SCLC makes up approximately 15% of all lung carcinomas and is characterized by relatively aggressive spread and poorer prognosis compared to other lung cancers. …”
Publicado 2019
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147945“…Pancreatic ductal adenocarcinoma (PDAC) is a class of the commonest malignant carcinomas. The present study aimed to elucidate the potential biomarker and prognostic targets in PDAC. …”
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147946por Li, Meng, Li, Anqi, He, Ruiqing, Dang, Wenhui, Liu, Xinyu, Yang, Tian, Shi, Puyu, Bu, Xiang, Gao, Dan, Zhang, Ning, Du, Shuli, Jin, Tianbo, Chen, Mingwei“…Similar association of this variant was also found in the subgroups of male patients, cases in III‐IV stages, positive lymph node, squamous cell carcinomas and adenocarcinomas. Whereas rs1065852 was considered as protective factor in females (adjusted OR = 0.33, 95% CI = 0.16‐0.70, P = 0.004). …”
Publicado 2019
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147947“…Germline and somatic BRCA1/2 mutations have been widely studied in breast and ovarian carcinomas as they have been found to enhance the risk for disease progression. …”
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147948por Wang, Qing-Hua, Zhang, Min, Zhou, Ming-Hui, Gao, Xiao-Jiao, Chen, Fang, Yan, Xun, Lu, Feng“…Oncomine database analysis showed a higher expression of EIF3M expression in colon adenocarcinoma compared with normal colon tissues, colon squamous cell carcinomas or gastrointestinal stromal tumors. In conclusion, EIF3M expression was associated with tumor size and Dukes' stage in colon adenocarcinoma. …”
Publicado 2020
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147949“…INTRODUCTION: Intrahepatic cholangiocarcinoma (ICC) accounts for 10% to 15% of all primary hepatic carcinomas. However, there are no effective drug treatment strategies against ICC, and surgery is currently the only curative treatment. …”
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147950por Dong, Zhengwei, Liu, Yiwei, Jiang, Tao, Hou, Likun, Wu, Fengying, Gao, Guanghui, Li, Xuefei, Zhao, Chao, Wang, Yan, Yang, Shuo, Mao, Shiqi, Liu, Qian, Li, Yumei, Xu, Chuan, Wu, Chunyan, Ren, Shengxiang, Zhou, Caicun, Zhang, Jun, Hirsch, Fred R.“…Results: A total of 112 pairs of specimens were collected, including 68(60.7%) adenocarcinomas and 28(25.0%) squamous cell carcinomas. Based on a tumor proportion score (TPS) cutoff of 1% for the 28-8 and SP142 assays, PD-L1 expression was positive in 78.6% and 58.9% of surgical samples respectively, while PD-L1 expression was positive in 67.9% and 25.0% of cytological cell block samples. …”
Publicado 2020
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147951“…Lymphomas and sarcomas showed the lowest calculated mean ADC values, 0.7 and 0.79 × 10(−3) mm(2)/s, respectively. Adenoid cystic carcinomas had the highest ADC values (1.5 × 10(−3) mm(2)/s). …”
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147952por Cheng, Angela S., Leung, Samuel C. Y., Gao, Dongxia, Burugu, Samantha, Anurag, Meenakshi, Ellis, Matthew J., Nielsen, Torsten O.“…PURPOSE: Alterations to mismatch repair (MMR) pathways are a known cause of cancer, particularly colorectal and endometrial carcinomas. Recently, checkpoint inhibitors have been approved for use in MMR-deficient cancers of any type (Prasad et al. in JAMA Oncol 4:157–158, 2018). …”
Publicado 2019
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147953por Rangabashyam, Mahalakshmi, Wee, Hide E., Wang, Weining, Mueller, Stefan, Karim, Khairul A. B. A., Skanthakumar, Thakshayeni, Hariraman, Bhuvaneshwari, Sommat, Kiattisa, Soong, Yoke‐Lim, Chua, Melvin L. K., Tay, Gerald, Tan, Ngian ‐Chye, Tan, Hiang Khoon‐, Iyer, N. Gopalakrishna“…The most common cancers were squamous cell (523, 41%), thyroid (207, 16%), and nasopharyngeal (139, 11%) carcinomas. Importantly, this system has formed the basis for a number of clinical and translational research projects and audit outcomes. …”
Publicado 2020
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147954por Leiting, Jennifer L., Murphy, Stephen J., Bergquist, John R., Hernandez, Matthew C., Ivanics, Tommy, Abdelrahman, Amro M., Yang, Lin, Lynch, Isaac, Smadbeck, James B., Cleary, Sean P., Nagorney, David M., Torbenson, Michael S., Graham, Rondell P., Roberts, Lewis R., Gores, Gregory J., Smoot, Rory L., Truty, Mark J.“…RESULTS: Between October 2013 and January 2018, 87 patients with histologically confirmed biliary tract carcinomas were enrolled. Of the 87 patients, 47 validated PDX models were successfully generated. …”
Publicado 2020
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147955por Gaibar, Maria, Beltrán, Laura, Romero-Lorca, Alicia, Fernández-Santander, Ana, Novillo, Apolonia“…In one of every four or five cases of breast cancer, the human epidermal growth factor receptor-2 (HER2) gene is overexpressed. These carcinomas are known as HER2-positive. HER2 overexpression is linked to an aggressive phenotype and a lower rate of disease-free and overall survival. …”
Publicado 2020
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147956por Xu, Qian, Yuan, Jing-Ping, Chen, Yuan-Yuan, Zhang, Hong-Yan, Wang, Lin-Wei, Xiong, Bin“…BACKGROUND: Previous studies have demonstrated that the tumor-stromal ratio (TSR) was an independent prognostic factor in several types of carcinomas. This study aimed at exploring the prognostic significance of the TSR in invasive breast cancer using immunohistochemistry (IHC)-stained tissue microarrays (TMAs) and integrating the TSR into the traditional tumor-node-metastasis (TNM) staging system. …”
Publicado 2020
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147957por Ostorga, Antonio Dono, Hines, Gabriella, Moghadamtous, Soheil Zorofchian, Esquenazi, Yoshua, Ballester, Leomar Y“…We performed a retrospective review of genomic alterations in 154 patients with BM from various primary sites (80 Lung, 22 Breast, 16 Melanoma, 5 Kidney, 4 Colorectal, 4 Prostate, and 23 carcinomas from unknown primary (UP). All cases were analyzed by a next generation sequencing assay the detects mutations in the coding region of 327 genes and rearrangements involving 37 genes. …”
Publicado 2019
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147958por Lombardo, Roberta, Tosi, Federica, Nocerino, Annunziata, Bencardino, Katia, Gambi, Valentina, Ricotta, Riccardo, Spina, Francesco, Siena, Salvatore, Sartore-Bianchi, Andrea“…Background: Carcinomas of unknown primary (CUP) account for 3–5% of all malignancy and, despite a reduction in incidence, the overall survival has not improved over the last decade. …”
Publicado 2020
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147959por Gornjec, Andreja, Merlo, Sebastijan, Novakovic, Srdjan, Stegel, Vida, Gazic, Barbara, Perhavec, Andraz, Blatnik, Ana, Krajc, Mateja“…We identified four non-invasive serous intraepithelial tubal carcinomas (3 in BRCA1 carriers and 1 in a high-risk BRCA1/2 negative woman) and five invasive tubo-ovarian high grade serous cancers (all detected in BRCA1 carriers). …”
Publicado 2020
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147960por Tőkés, Tímea, Tőkés, Anna-Mária, Szentmártoni, Gyöngyvér, Kiszner, Gergő, Mühl, Dorottya, Molnár, Béla Ákos, Kulka, Janina, Krenács, Tibor, Dank, Magdolna“…We aimed to analyze the expression of cell-cycle regulation markers – minichromosome maintenance protein 2 (MCM2), Ki-67, Cyclin-A and phosphohistone-H3 (PHH3) − in pre-treatment core-biopsy samples of breast carcinomas in correlation with known predictive and prognostic factors. …”
Publicado 2019
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