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147961por Tinguely, Pascale, Frehner, Lorenz, Lachenmayer, Anja, Banz, Vanessa, Weber, Stefan, Candinas, Daniel, Maurer, Martin H.“…Results: Three hundred one lesions (174 hepatocellular carcinomas, 87 colorectal liver metastases, 17 neuroendocrine tumors, and 23 others) were targeted in 191 interventions in 153 patients. …”
Publicado 2020
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147962por Flammang, Isabelle, Reese, Moritz, Yang, Zixuan, Eble, Johannes A., Dhayat, Sameer A.“…Previous studies could demonstrate an involvement of miR-192-5p in epigenetic regulation of visceral carcinomas. Due to contradictory results, however, the clinical utility of miR-192-5p in PDAC has yet to be determined. …”
Publicado 2020
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147963por Schrenk, Dieter, Bignami, Margherita, Bodin, Laurent, Chipman, James Kevin, del Mazo, Jesús, Grasl‐Kraupp, Bettina, Hogstrand, Christer, Hoogenboom, Laurentius (Ron), Leblanc, Jean‐Charles, Nebbia, Carlo Stefano, Nielsen, Elsa, Ntzani, Evangelia, Petersen, Annette, Sand, Salomon, Schwerdtle, Tanja, Vleminckx, Christiane, Marko, Doris, Oswald, Isabelle P, Piersma, Aldert, Routledge, Michael, Schlatter, Josef, Baert, Katleen, Gergelova, Petra, Wallace, Heather“…Aflatoxins are genotoxic and AFB1 can cause hepatocellular carcinomas (HCCs) in humans. The CONTAM Panel selected a benchmark dose lower confidence limit (BMDL) for a benchmark response of 10% of 0.4 μg/kg body weight (bw) per day for the incidence of HCC in male rats following AFB1 exposure to be used in a margin of exposure (MOE) approach. …”
Publicado 2020
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147964Investigating split‐filter dual‐energy CT for improving liver tumor visibility for radiation therapypor DiMaso, Lianna D., Miller, Jessica R., Lawless, Michael J., Bassetti, Michael F., DeWerd, Larry A., Huang, Jessie“…METHODS: Split‐filter DECT contrast‐enhanced scans of 20 liver tumors including cholangiocarcinomas, hepatocellular carcinomas, and liver metastases were acquired. Analysis was performed on the arterial and venous phases of mixed 120 kVp‐equivalent images and VMIs at 57 keV and 40 keV gross target volume (GTV) contrast and CNR were calculated. …”
Publicado 2020
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147965por Gu, Weijie, Zhang, Peipei, Zhang, Guiming, Zhou, Jiaquan, Ding, Xuefei, Wang, Qifeng, Wang, Beihe, Wei, Yu, Jin, Shengming, Ye, Dingwei, Zhu, Yao“…Standardized HPV DNA detection and p16(INK4a) expression were used in a multi-center series of 340 penile squamous cell carcinomas diagnosed from 2006 to 2017. Materials and Methods: HPV DNA detection and genotyping were examined by a validated kit for 23 different HPV subtypes (PCR-RDB HPV test). …”
Publicado 2020
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147966por Zhang, Yuchen, Jiang, Chang, Trudeau, Stephen J., Narita, Yohei, Zhao, Bo, Teng, Mingxiang, Guo, Rui, Gewurz, Benjamin E.“…EBV is associated with endemic Burkitt lymphoma, Hodgkin lymphoma, posttransplant lymphomas, nasopharyngeal and gastric carcinomas. In these cancers and in most infected B-cells, EBV maintains a state of latency, where nearly 80 lytic cycle antigens are epigenetically suppressed. …”
Publicado 2020
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147967por Uhlig, Johannes, Leha, Andreas, Delonge, Laura M., Haack, Anna-Maria, Shuch, Brian, Kim, Hyun S., Bremmer, Felix, Trojan, Lutz, Lotz, Joachim, Uhlig, Annemarie“…In total, n = 201 patients were included (73.7% male; mean age 66 ± 11 years), with n = 131 clear cell renal cell carcinomas (ccRCC), n = 29 papillary RCC, n = 11 chromophobe RCC, n = 16 oncocytomas, and n = 14 angiomyolipomas (AML). …”
Publicado 2020
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147968KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profilingpor Gimeno, Lourdes, Serrano-López, Emilio M., Campillo, José A., Cánovas-Zapata, María A., Acuña, Omar S., García-Cózar, Francisco, Martínez-Sánchez, María V., Martínez-Hernández, María D., Soto-Ramírez, María F., López-Cubillana, Pedro, Martínez-Escribano, Jorge, Martínez-García, Jerónimo, Corbalan-García, Senena, Álvarez-López, María R., Minguela, Alfredo“…With this objective, frequencies of different KIR+ CD8+ T cell subsets are correlated with the overall survival of patients with melanoma, ovarian and bladder carcinomas. In addition, the gene expression profile of KIR+ CD8+ T cell subsets related to the survival of patients is studied with the aim of discovering new therapeutic targets, so that the outcome of patients with cancer can be improved. …”
Publicado 2020
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147969“…Among them, 41 were non-adenomas, 110 were low-risk adenomas, 139 were high-risk adenomas, and 5 were carcinomas. The differences in distribution were not statistically significant, with P values greater than 0.05. …”
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147970por Pellizzon, Antonio Cassio Assis, Fogaroli, Ricardo, Chen, Michael Jenwey, Maia, Polyana, Gondim, Guilherme, Guedes, Douglas de Castro, Ramos, Henderson, Silva, Maria Leticia Gobo“…We reviewed our single institutional experience using HDR to treat basal (BCC) and squamous cell (SCC) carcinomas. MATERIAL AND METHODS: A retrospective review of all patients treated with HDR and Leipzig-style applicators for NMSC at the Radiation Oncology Department, AC Camargo Cancer Center, from March 2013 to December 2018 was performed. …”
Publicado 2020
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147971por Shashi, Kumar K., Madan, Rachna, Hammer, Mark M., van Hedent, Steven, Byrne, Suzanne C., Schmidlin, Eric J., Mamon, Harvey, Hatabu, Hiroto, Enzinger, Peter C., Gerbaudo, Victor H.“…RESULTS: 79 patients (61 males and 18 females; median age, 61 years, range, 33–86) with esophageal cancer (53 adenocarcinomas and 26 squamous cell carcinomas) were included. The contribution of PET/CT-derived information was as follows: category I in 50 patients (63%); category II in 3 patients (4%); category III in 8 patients (10%), and category IV information in 18 patients (23%). …”
Publicado 2020
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147972por Harrandah, Amani M., Chukkapalli, Sasanka S., Bhattacharyya, Indraneel, Progulske-Fox, Ann, Chan, Edward K. L.“…Abbreviations: 4NQO, 4-nitroquinoline-1-oxide; ELISA, enzyme-linked immunosorbent assay; EMT, epithelial–mesenchymal transition; IL-8, interleukin-8; JAK1, Janus kinase 1; LPS, lipopolysaccharide; MMP, matrix metalloproteinase; OSCCs, oral squamous cell carcinomas; PK, proteinase K; PMB, Polymyxin B; qRT-PCR, quantitative real-time polymerase chain reaction; STAT3, signal transducer and activator of transcription 3; TGF-β, transforming growth factor beta; ZEB1, zinc finger E-Box binding homeobox 1…”
Publicado 2020
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147973por Vanni, Kathleen M.M., Berliner, Nancy, Paynter, Nina P., Glynn, Robert J., MacFadyen, Jean, Colls, Joshua, Lu, Fengxin, Xu, Chang, Ridker, Paul M., Solomon, Daniel H.“…We found more cases of skin cancer, particularly squamous cell carcinomas, in the LD‐MTX arm than the placebo arm.…”
Publicado 2020
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147974por Stanitsas, Panagiotis, Cherian, Anoop, Morellas, Vassilios, Tejpaul, Resha, Papanikolopoulos, Nikolaos, Truskinovsky, Alexander“…Material and Methods: We start with a patch level descriptor, termed Covariance-Kernel Descriptor (CKD), capable of compactly describing tissue architectures associated with carcinomas. To leverage the recognition capability of the CKDs to larger slide regions, we resort to a multiple instance learning framework. …”
Publicado 2020
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147975“…The most common malignancies were lung cancer (59.7%), melanoma (23.1%), renal cell and urothelial carcinomas (8.1%). OS and PFS were shorter, RR lower, and PD higher in patients receiving antibiotics, both in univariate analyses and after adjustment for other confounders. …”
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147976por Alldredge, Jill, Randall, Leslie, De Robles, Gabriela, Agrawal, Anshu, Mercola, Dan, Liu, Marisa, Randhawa, Pavneet, Edwards, Robert, McClelland, Michael, Rahmatpanah, Farah“…PURPOSE: Ovarian and uterine clear cell carcinomas (CCCs) are rare but associated with poor prognosis. …”
Publicado 2020
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147977por Zheng, Hua-chuan, Zhao, Shuang, Xue, Hang, Zhao, En-hong, Jiang, Hua-mao, Hao, Chang-lai“…Bioinformatics analysis showed higher Becn1 mRNA expression in intestinal- than diffuse-type carcinomas (P<0.05), and in male than female gastric cancer patients (P<0.05). …”
Publicado 2020
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147978por Nakata, Mio, Yoshida, Ken, Shimbo, Taiju, Yoshikawa, Nobuhiko, Yoshioka, Hiroto, Hori, Akihiro, Sato, Chikara, Uesugi, Yasuo, Kogata, Yuhei, Masui, Koji, Murakami, Naoya, Kashihara, Tairo, Akiyama, Hironori, Tselis, Nikolaos, Ohmichi, Masahide, Nihei, Keiji“…In order to improve oncologic outcomes in radiotherapy treatments of patients with unresectable pelvic sidewall recurrences of uterine cervical cancer, we combined high-dose-rate interstitial brachytherapy (HDR-ISBT) with newly tested hypoxic radiosensitizer Kochi oxydol-radiation therapy for unresectable carcinomas (KORTUC II), an enzyme-targeting radiosensitization treatment involving intra-tumoral injection of sodium hyaluronate mixed with hydrogen peroxide. …”
Publicado 2020
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147979por Garcia-Escolano, Marta, Montoyo-Pujol, Yoel G., Ortiz-Martinez, Fernando, Ponce, Jose J., Delgado-Garcia, Silvia, Martin, Tina A., Ballester, Hortensia, Aranda, F. Ignacio, Castellon-Molla, Elena, Sempere-Ortells, J. Miguel, Peiro, Gloria“…We studied the mRNA expression of all ID genes by q RT-PCR in BC cell lines and 307 breast carcinomas, including all BC subtypes. Our results showed that ID genes are highly expressed in all cell lines tested. …”
Publicado 2021
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147980por James, Claire D., Saini, Siddharth, Sesay, Fatmata, Ko, Kevin, Felthousen-Rusbasan, Jessica, Iness, Audra N., Nulton, Tara, Windle, Brad, Dozmorov, Mikhail G., Morgan, Iain M., Litovchick, Larisa“…ABSTRACT: High-risk (HR) human papillomaviruses are known causative agents in 5% of human cancers including cervical, ano-genital and head and neck carcinomas. In part, HR-HPV causes cancer by targeting host-cell tumor suppressors including retinoblastoma protein (pRb) and RB-like proteins p107 and p130. …”
Publicado 2021
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