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148001por Dunton, Charles J., Hutchcraft, Megan L., Bullock, Rowan G., Northrop, Lesley E., Ueland, Frederick R.“…The most common epithelial ovarian cancer subtypes in the study population were mucinous (25%) and serous (23%) carcinomas. Despite a low-risk CA125, OVA1 successfully detected 83% of serous, 58% of mucinous, and 50% of clear cell ovarian cancers. …”
Publicado 2021
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148002por Hu, Xiaofeng, Xing, Hongru, Wang, Xiaofeng, Du, Lei, Huang, Yihong, Hao, Youguo, Shen, Zhibin“…LncRNA SNHG1 (SNHG1) has been widely studied as the causative factor of angiogenesis and proliferative agent in gastric, lung, cervical, and hepatocellular carcinomas. However, its significance of angiogenesis and progression of corneal neovascularization (CRNV) is least understood. …”
Publicado 2021
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148003por Faron, Matthieu, Blanchard, Pierre, Ribassin-Majed, Laureen, Pignon, Jean-Pierre, Michiels, Stefan, Le Teuff, Gwénaël“…These models were applied to the NMA (Meta-analyses of Chemotherapy in Head and Neck Cancer [MACH-NC] and Radiotherapy in Carcinomas of Head and Neck [MARCH]), which compared the addition of chemotherapy or modified radiotherapy (mRT) to loco-regional treatment with two direct comparisons. …”
Publicado 2021
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148004por Ashourpour, Maryam, Mostafavi-Hosseini, Fatemeh, Amini, Mohsen, Saeedian Moghadam, Ebrahim, Kazerouni, Faranak, Arman, Seyed Yousef, Shahsavari, Zahra“…BACKGROUND: Triple-negative breast cancer accounts for approximately 15–20% of all breast carcinomas and is associated with earlier age of onset, aggressive clinical course, and dismal prognosis. …”
Publicado 2021
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148005“…Computer-assisted subjective interpretation using KSThR is more ideal for ruling out papillary thyroid carcinomas than CAD. Future larger multi-center and multi-rater prospective studies with a diverse representation of thyroid cancers are necessary to validate these findings.…”
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148006por Pellino, Antonio, Brignola, Stefano, Riello, Erika, Niero, Monia, Murgioni, Sabina, Guido, Maria, Nappo, Floriana, Businello, Gianluca, Sbaraglia, Marta, Bergamo, Francesca, Spolverato, Gaya, Pucciarelli, Salvatore, Merigliano, Stefano, Pilati, Pierluigi, Cavallin, Francesco, Realdon, Stefano, Farinati, Fabio, Dei Tos, Angelo Paolo, Zagonel, Vittorina, Lonardi, Sara, Loupakis, Fotios, Fassan, Matteo“…In this study, we aim to evaluate the immunohistochemical profile of CLDN18 in a real-world and mono-institutional series of gastric and gastroesophageal carcinomas. The association of CLDN18 expression with clinicopathological features and survival outcomes was investigated. …”
Publicado 2021
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148007por Neal, Adam, Lai, Tiffany, Singh, Tanya, Rahseparian, Neela, Grogan, Tristan, Elashoff, David, Scott, Peter, Pellegrini, Matteo, Memarzadeh, Sanaz“…High-grade serous ovarian carcinomas (HGSOCs), the most common ovarian cancer subtype, are aggressive tumors with poor outcomes. …”
Publicado 2021
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148008por Locati, Laura D., Cavalieri, Stefano, Bergamini, Cristiana, Resteghini, Carlo, Colombo, Elena, Calareso, Giuseppina, Mariani, Luigi, Quattrone, Pasquale, Alfieri, Salvatore, Bossi, Paolo, Platini, Francesca, Capone, Iolanda, Licitra, Lisa“…The activity of androgen-deprivation therapy (ADT) in androgen receptor–positive (AR+) salivary gland carcinomas (SGCs) has been established in the past few years. …”
Publicado 2021
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148009por Li, Junjie, Wang, Jing, Su, Dan, Nie, Xiu, Liu, Yueping, Teng, Lianghong, Pang, Junyi, Wu, Huanwen, Liang, Zhiyong“…RESULTS: The cohort included 35 well-differentiated neuroendocrine tumors and 57 poorly differentiated neuroendocrine carcinomas. Gene sequencing revealed 38 wild-type TP53 and 54 TP53 mutations. p53 expression was interpreted as follows: pattern A, p53 was absent from all tumor cells; pattern B, scattered and weak p53 expression in 1-20% of tumor cells; and pattern C was subclassified as pattern C1: variable p53 staining intensity in 21-60% of tumor cells and tumor cell nests with focal strong positive p53 staining and pattern C2: strong p53 staining in more than 60% of tumor cells. p53 IHC patterns were evaluated as a binary classifier where pattern B predicted wild-type TP53, and patterns A and C predicted TP53 mutations. …”
Publicado 2021
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148010por Lampe, Björn, Luengas-Würzinger, Verónica, Weitz, Jürgen, Roth, Stephan, Rawert, Friederike, Schuler, Esther, Classen-von Spee, Sabrina, Fix, Nando, Baransi, Saher, Dizdar, Anca, Mallmann, Peter, Schaser, Klaus-Dieter, Bogner, Andreas“…Results: A complete tumour resection (R0) often represents the only curative option for advanced pelvic carcinomas and their recurrences. A recent systematic review showed significant symptom relief in 80% of palliative patients after pelvic exenteration. …”
Publicado 2021
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148011“…Using TCGA and METABRIC microarray expression data from invasive breast cancer carcinomas, we also observed that higher levels of ER-beta were associated with higher levels of IGF-IR. …”
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148012por Johnson, Kelsey S., Hussein, Shaimaa, Chakraborty, Priyanka, Muruganantham, Arvind, Mikhail, Sheridan, Gonzalez, Giovanny, Song, Shuxuan, Jolly, Mohit Kumar, Toneff, Michael J., Benton, Mary Lauren, Lin, Yin C., Taube, Joseph H.“…ABSTRACT: Epithelial–mesenchymal transition (EMT) and its reversal, mesenchymal–epithelial transition (MET) drive tissue reorganization critical for early development. In carcinomas, processing through EMT, MET, or partial states promotes migration, invasion, dormancy, and metastatic colonization. …”
Publicado 2022
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148013por Wang, Jiaqi, Yokoyama, Yuhki, Hirose, Haruka, Shimomura, Yuki, Bonkobara, Saki, Itakura, Hiroaki, Kouda, Shihori, Morimoto, Yoshihiro, Minami, Kazumasa, Takahashi, Hidekazu, Shibata, Satoshi, Kobayashi, Shogo, Uemura, Mamoru, Tanaka, Susumu, Wu, Xin, Tanaka, Shinji, Mori, Masaki, Yamamoto, Hirofumi“…miR-1291 exerts an anti-tumor effect in a subset of human carcinomas, including pancreatic cancer. However, its role in colorectal cancer (CRC) is largely unknown. …”
Publicado 2022
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148014por Mustufa, Muhammad Ayaz, Zia, Zubia, Ilyas, Rabia, Khan, Rehan, Naqvi, Syed Naim Ul Hasan, Ali, Firdous Imran“…A literature review of recent studies has revealed that a number of hepatocellular carcinomas (HCC) cases are markedly increased in Pakistan, where one of the potential causes of HCC is hepatitis C virus. …”
Publicado 2021
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148015por Tham, Marius, Stark, Hans-Jürgen, Jauch, Anna, Harwood, Catherine, Pavez Lorie, Elizabeth, Boukamp, Petra“…The BRAF inhibitor vemurafenib, approved for treating patients with BRAF V600E-mutant and unresectable or metastatic melanomas, rapidly induces cutaneous adverse events, including hyperkeratotic skin lesions and cutaneous squamous cell carcinomas (cSCC). To determine, how vemurafenib would provoke these adverse events, we utilized long-term in vitro skin equivalents (SEs) comprising epidermal keratinocytes and dermal fibroblasts in their physiological environment. …”
Publicado 2022
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148016“…In univariate analyses, Ki67 expression ≥20%, HR negative, neuroendocrine carcinomas (NECs) were associated with decreased OS and DFS (P < 0.05). …”
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148017por Weber, Jean-Philip Daniel, Spiro, Judith Eva, Scheffler, Matthias, Wolf, Jürgen, Nogova, Lucia, Tittgemeyer, Marc, Maintz, David, Laue, Hendrik, Persigehl, Thorsten“…DCE-MRI allowed a quantitative measurement of K(trans) in 107 tumors where 91 were primary carcinomas or intrapulmonary metastases and 16 were extrapulmonary metastases. …”
Publicado 2022
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148018por Ayyad, Sarah M., Badawy, Mohamed A., Shehata, Mohamed, Alksas, Ahmed, Mahmoud, Ali, Abou El-Ghar, Mohamed, Ghazal, Mohammed, El-Melegy, Moumen, Abdel-Hamid, Nahla B., Labib, Labib M., Ali, H. Arafat, El-Baz, Ayman“…The dataset presented in the paper includes 80 biopsy confirmed patients, with a mean age of 65.7 years (43 benign prostatic hyperplasia, 37 prostatic carcinomas). Experiments were conducted using different well-known machine learning approaches including support vector machines (SVM), random forests (RF), decision trees (DT), and linear discriminant analysis (LDA) classification models to study the impact of different feature sets that lead to better identification of prostatic adenocarcinoma. …”
Publicado 2022
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148019“…Muscle-invasive lethal carcinomas traverse into and through this specialized biophysical and growth factor enriched microenvironment. …”
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148020“…BACKGROUND: The expression of calcium signaling pathway molecules is altered in various carcinomas, which are related to the proliferation and altered characteristics of cancer cells. …”
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