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Mostrando 221 - 240 Resultados de 7,810 Para Buscar '"cassette"', tiempo de consulta: 0.10s Limitar resultados
  1. 221
    “…Among the various types of transporters, ATP-binding cassette (ABC) importers are essentially unique to bacteria, accessible as drug targets without penetrating the cytoplasmic membrane, and offer an ATP-dependent gateway into the cell by mimicking substrates of the importer and designing inhibitors against substrate-binding proteins, ABC importers endeavour for the development of successful drug candidates and antibiotics. …”
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    ATP-binding cassette (ABC) import systems of Mycobacterium tuberculosis: target for drug and vaccine development
  2. 222
    “…Moreover, other, not carried by gene cassettes, aminoglycoside resistance genes, strA-strB and aph(3’)-IIIa, were also detected. …”
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    New Determinants of Aminoglycoside Resistance and Their Association with the Class 1 Integron Gene Cassettes in Trueperella pyogenes
  3. 223
    por Zhang, Zhaoxi, Wang, Juan, Liu, Jiameng
    Publicado 2021
    “…ATP-binding cassette (ABC) transporters can promote cells to absorb nutrients and excrete harmful substances. …”
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    DeepRTCP: Predicting ATP-Binding Cassette Transporters Based on 1-Dimensional Convolutional Network
  4. 224
    “…In the present study, we identified a novel regulatory protein SRSF9 for AS of Caspase-2 cassette exon 9. Knock-down (KD) of SRSF9 increased inclusion of cassette exon and on the other hand, overexpression of SRSF9 decreased inclusion of this exon. …”
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    SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon
  5. 225
    “…We explored the potential clinical significance for LUAD of ATP-binding cassette (ABC), sub-family C, consisting of ABCC1–6, 8–12, and cystic fibrosis transmembrane conductance regulator (CFTR). …”
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    Varied clinical significance of ATP-binding cassette C sub-family members for lung adenocarcinoma
  6. 226
    “…RESULTS: Sequence analysis revealed a new staphylococcal cassette chromosome mec (SCCmec) structure in isolate UMCG335. …”
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    Staphylococcal cassette chromosome mec containing a novel mec gene complex, B4
  7. 227
    “…Transfer of the cloned ars cassette to X. oryzae pv. oryzae BXO512, which lacks the cassette, confers an arsenic-resistance phenotype. …”
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    Discerning the role of a functional arsenic-resistance cassette in the evolution and adaptation of a rice pathogen
  8. 228
    “…In this study, an ATP-binding cassette (ABC) transporter from Lycoris aurea (L’Hér) Herb., namely LaABCB11, was cloned and functionally characterized. …”
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    An ATP-Binding Cassette Transporter, LaABCB11, Contributes to Alkaloid Transport in Lycoris aurea
  9. 229
    “…All cassettes included nisin promoter, protein encoding gene and transcription terminator. …”
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    Introduction of Modified BglBrick System in Lactococcus lactis for Straightforward Assembly of Multiple Gene Cassettes
  10. 230
    “…The toxicity of aluminum (Al) in acidic soil limits global crop yield. The ATP-binding cassette (ABC) transporter-like gene superfamily has functions and structures related to transportation, so it responds to aluminum stress in plants. …”
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    Identification of an ATP-Binding Cassette Transporter Implicated in Aluminum Tolerance in Wild Soybean (Glycine soja)
  11. 231
    “…The purpose of this investigation was to assess the diagnostic and prognostic significance of ATP binding cassette subfamily C (ABCC) genes in hepatocellular carcinoma (HCC). …”
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    Clinical Significance and Potential Mechanisms of ATP Binding Cassette Subfamily C Genes in Hepatocellular Carcinoma
  12. 232
    “…We report that the human malaria parasite Plasmodium falciparum (Pf) expresses a C-type ATP-binding cassette transporter, Pf ABCC2, which marks the transition from invasive sporozoite to intrahepatocytic early liver stage. …”
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    A Plasmodium falciparum ATP-binding cassette transporter is essential for liver stage entry into schizogony
  13. 233
    “…Multitarget datasets that correlate bioactivity landscapes of small-molecules toward different related or unrelated pharmacological targets are crucial for novel drug design and discovery. ATP-binding cassette (ABC) transporters are critical membrane-bound transport proteins that impact drug and metabolite distribution in human disease as well as disease diagnosis and therapy. …”
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    A curated binary pattern multitarget dataset of focused ATP-binding cassette transporter inhibitors
  14. 234
    “…The human brain is highly enriched in lipids and increasing evidence indicates that dysregulation of lipids in the brain is associated with neurodegeneration. ATP-binding cassette subfamily A (ABCA) transporters control the movement of lipids across cellular membranes and are implicated in a number of neurodegenerative diseases. …”
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    ATP-binding cassette transporter expression is widely dysregulated in frontotemporal dementia with TDP-43 inclusions
  15. 235
    “…Chemotherapy resistance is the main cause of treatment failure in acute myeloid leukemia (AML) and has been related to ATP-binding cassette (ABC) transporter activity. However, the links between ABC activity, immunophenotype, and molecular AML parameters have been poorly evaluated. …”
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    Clinical and biological impact of ATP-binding cassette transporter activity in adult acute myeloid leukemia
  16. 236
    “…Down-regulation of SRSF6 is achieved through inclusion of a poison cassette exon (PCE) promoted by SRSF4. Removing the PCE 3′ splice site using CRISPR/Cas9 abolishes SRSF6 reduction in hypoxia. …”
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    Poison cassette exon splicing of SRSF6 regulates nuclear speckle dispersal and the response to hypoxia
  17. 237
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    TLN1 contains a cancer-associated cassette exon that alters talin-1 mechanosensitivity
  18. 238
    “…A mutation in the ambiguous lysis cassette (ALC) region abolished exoprotein release and caused cell elongation, a phenotype able to be restored through trans-complementation with an intact ALC region. …”
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    Lysis Cassette-Mediated Exoprotein Release in Yersinia entomophaga Is Controlled by a PhoB-Like Regulator
  19. 239
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    A Widely Distributed Biosynthetic Cassette Is Responsible for Diverse Plant Side Chain Cross‐Linked Cyclopeptides
  20. 240
    “…Short interrupted repeat cassette (SIRC)—a novel DNA element found throughout the A. thaliana nuclear genome. …”
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    Short Interrupted Repeat Cassette (SIRC)—Novel Type of Repetitive DNA Element Found in Arabidopsis thaliana
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