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581“…Taking advantage of these aspects, chemists and chemical engineers have capitalized on expanding the chemical space available to synthetic organic chemists using this technology. …”
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582“…Of interest for lecturers in physics, theoretical physicists and chemists, as well as chemical engineers.…”
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583por March, N H“…This reference describes the latest research on correlation effects in the multicenter problems of atoms, molecules, and solids The author utilizes first- and second-order matrices, including the important observable electron density rho(r), and the Green function for discussing quantum computer simulations With its focus on concepts and theories, this volume will benefit experimental physicists, materials scientists, and physical and inorganic chemists as well as graduate students…”
Publicado 1996
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584“…Of interest for lecturers in physics, theoretical physicists and chemists, as well as chemical engineers.…”
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585“…These molecules have therefore attracted the attention of chemists and biologists for their further studies towards potential drug leads. …”
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586“…The 25th Conference of GP2A was held on 31 August and 1 September 2017 in Liverpool, UK, with the aim of exchange of ideas and experience, particularly amongst young medicinal chemists. Topics included bioactive compounds from plants and lichens, and design and development of drugs. …”
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587por Martinand-Lurin, Elodie, Dos Santos, Aurélie, Robineau, Emmanuelle, Retailleau, Pascal, Dauban, Philippe, Grimaud, Laurence, El Kaïm, Laurent“…Initial conditions disclosed for the Passerini-Smiles reaction are associated with a lack of efficiency that has prevented chemists from using it since its discovery. We wish to report herein our thorough study in the development of new experimental conditions for this coupling between electron-poor phenols, isocyanides, and carbonyl derivatives. …”
Publicado 2016
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588“…They recently developed an interpretable framework to quantitatively assess the interpretability of Graph Neural Network (GNN) and made comparison with medicinal chemists. Their meaningful benchmarking and rigorous framework would greatly benefit development of new interpretable methods in GNNs.…”
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589por Kalaba, Predrag, Pacher, Katharina, Neill, Philip John, Dragacevic, Vladimir, Zehl, Martin, Wackerlig, Judith, Kirchhofer, Michael, Sartori, Simone B., Gstach, Hubert, Kouhnavardi, Shima, Fabisikova, Anna, Pillwein, Matthias, Monje-Quiroga, Francisco, Ebner, Karl, Prado-Roller, Alexander, Singewald, Nicolas, Urban, Ernst, Langer, Thierry, Pifl, Christian, Lubec, Jana, Leban, Johann Jakob, Lubec, Gert“…Ligand design itself is also rather limited, as many chemists, fully aware of the synthetic and analytical challenges, tend to modify lead compounds in a way that reduces the number of chiral centers and hence limits the potential chemical space of synthetic ligands. …”
Publicado 2023
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590por Huang, Zhimin, Zhu, Liang, Cao, Yan, Wu, Geng, Liu, Xinyi, Chen, Yingyi, Wang, Qi, Shi, Ting, Zhao, Yaxue, Wang, Yuefei, Li, Weihua, Li, Yixue, Chen, Haifeng, Chen, Guoqiang, Zhang, Jian“…Therefore, ASD could be a platform and a starting point for biologists and medicinal chemists for furthering allosteric research. ASD is freely available at http://mdl.shsmu.edu.cn/ASD/.…”
Publicado 2011
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591por Dockrey, Summer A. Baker, Suh, Carolyn E., Benítez, Attabey Rodríguez, Wymore, Troy, Brooks, Charles L., Narayan, Alison R. H.“…Proven strategies exist for optimizing the performance of a biocatalyst toward unnatural substrates, including protein engineering; however, these methods can be time intensive and require specialized equipment that renders these approaches inaccessible to synthetic chemists. Strategies accessible to chemists for the expansion of a natural enzyme’s substrate scope, while maintaining high levels of site- and stereoselectivity, remain elusive. …”
Publicado 2019
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592“…We believe this deep learning-based web server will benefit to both biologists and chemists for probes or drugs discovery.…”
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593por Kim, Hyun Woo, Choi, Seong Yeon, Jang, Hyeon Seok, Ryu, Byeol, Sung, Sang Hyun, Yang, Heejung“…Many natural product chemists are working to identify a wide variety of novel secondary metabolites from natural materials and are eager to avoid repeatedly discovering known compounds. …”
Publicado 2019
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594por Hoang Thi, Thai Thanh, Pilkington, Emily H., Nguyen, Dai Hai, Lee, Jung Seok, Park, Ki Dong, Truong, Nghia P.“…To achieve asatisfactory alternative, further joint efforts of polymer chemists and scientists in related fields are urgently needed to design, synthesize and evaluate new alternatives to PEG.…”
Publicado 2020
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595por Hagarová, Ingrid“…The results presented herein show the great analytical potential of MSPE procedures in connection with spectrometric methods used in these fields and can be helpful in guiding analytical chemists who aim to work on this subject.…”
Publicado 2020
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596“…The chemistry and biology of this group have attracted the attention of chemists, medicinal chemists, and professionals in health sciences. …”
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597“…Therefore, medicinal chemists working to design an integrated and developing system that portends an era of novel and safe tailored drugs either by synthesizing new pharmaceuticals or to improving the processes by which existing pharmaceuticals are made. …”
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598por Xing, Junfei, Takeuchi, Keishi, Kamei, Ko, Nakamuro, Takayuki, Harano, Koji, Nakamura, Eiichi“…The molecular models will stimulate the imaginations of chemists planning to use AR-TEM for their research.…”
Publicado 2022
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599por Arshad, Mohammed F., Alam, Aftab, Alshammari, Abdullah Ayed, Alhazza, Mohammed Bader, Alzimam, Ibrahim Mohammed, Alam, Md Anish, Mustafa, Gulam, Ansari, Md Salahuddin, Alotaibi, Abdulelah M., Alotaibi, Abdullah A., Kumar, Suresh, Asdaq, Syed Mohammed Basheeruddin, Imran, Mohd., Deb, Pran Kishore, Venugopala, Katharigatta N., Jomah, Shahamah“…Therefore, medicinal chemists have been focusing their efforts on thiazole-bearing compounds in order to develop novel therapeutic agents for a variety of pathological conditions. …”
Publicado 2022
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600por Silver, LynnEnlace del recurso
Publicado 2022
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