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701“…There are three groups of scientists dominating the search for the origin of life: the organic chemists (the Soup), the molecular biologists (RNA world), and the inorganic chemists (metabolism and transient-state metal ions), all of which have experimental adjuncts. …”
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702The importance of neopterin in COVID-19: The prognostic value and relation with the disease severitypor Rasmi, Yousef, Heidari, Nadia, Kübra Kırboğa, Kevser, Hatamkhani, Shima, Tekin, Burcu, Alipour, Shahryar, Naderi, Roya, Farnamian, Yeghaneh, Akca, IlknurEnlace del recurso
Publicado 2022
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703por Huang, Zhimin, Jiang, Haiming, Liu, Xinyi, Chen, Yingyi, Wong, Jiemin, Wang, Qi, Huang, Wenkang, Shi, Ting, Zhang, Jian“…CONCLUSIONS: HEMD could be a platform and a starting point for biologists and medicinal chemists for furthering research on epigenetic therapeutics. …”
Publicado 2012
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704por Kojima, Ryosuke, Ishida, Shoichi, Ohta, Masateru, Iwata, Hiroaki, Honma, Teruki, Okuno, Yasushi“…To leverage the power of GCN to benefit various users from chemists to cheminformaticians, an open-source GCN tool, kGCN, is introduced. …”
Publicado 2020
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705por Kumar, Devendra, Chauhan, Gaurav, Kalra, Sourav, Kumar, Bhupinder, Gill, Manjinder Singh“…These targets have attracted attention of the medicinal chemists working on computer-aided drug design in developing new small molecules that might inhibit these targets for combating COVID-19 disease. …”
Publicado 2020
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706“…Physicists and physical chemists have made great strides understanding the basic principles involved, and engineers have discovered a wide variety of new uses for fluid metals. …”
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707por Bernetti, Mattia, Aguti, Riccardo, Bosio, Stefano, Recanatini, Maurizio, Masetti, Matteo, Cavalli, Andrea“…Here, we embrace the perspective of computational chemists who use these traditional approaches, and we discuss the challenges of extending these methods to target RNA molecules. …”
Publicado 2022
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708“…Using digital cameras connected to computer vision algorithms, camera-enabled apparatus can perform some of these processes in an automated fashion, allowing skilled chemists to spend their time more productively. In this review we describe recent advances in this field of chemical synthesis and discuss how they will lead to advanced synthesis laboratories of the future.…”
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709“…This article examines the relationship between Research & Development (R&D) funding and the production of knowledge by academic chemists. Using articles published, either raw counts or adjusted for quality, we find a strong, positive causal effect of funding on knowledge production. …”
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710por Lécuyer, Thomas, Teston, Eliott, Ramirez-Garcia, Gonzalo, Maldiney, Thomas, Viana, Bruno, Seguin, Johanne, Mignet, Nathalie, Scherman, Daniel, Richard, Cyrille“…The optical activities of nanoprobes can be tuned on demand by chemists by engineering their composition, size and surface nature. …”
Publicado 2016
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711por Skoraczyński, G., Dittwald, P., Miasojedow, B., Szymkuć, S., Gajewska, E. P., Grzybowski, B. A., Gambin, A.“…As machine learning/artificial intelligence algorithms are defeating chess masters and, most recently, GO champions, there is interest – and hope – that they will prove equally useful in assisting chemists in predicting outcomes of organic reactions. …”
Publicado 2017
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712por Ramsay, Rona R., Popovic-Nikolic, Marija R., Nikolic, Katarina, Uliassi, Elisa, Bolognesi, Maria Laura“…This Perspective will focus on the molecular and computational approaches that underpin drug design by medicinal chemists to promote understanding and collaboration with clinical scientists.…”
Publicado 2018
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713“…[Image: see text] Pan-Assay Interference Compounds (PAINS) are very familiar to medicinal chemists who have spent time fruitlessly trying to optimize these nonprogressible compounds. …”
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714“…Some of these metabolites, with novel structures and promising biological activities, have attracted a lot of attention from chemists seeking to perform their total synthesis in parallel to intensive biological studies towards new drug leads. …”
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715“…The enormous challenge of moving our societies to a more sustainable future offers several exciting opportunities for computational chemists. The first principles approach to “catalysis by design” will enable new and much greener chemical routes to produce vital fuels and fine chemicals. …”
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716“…These models will help chemists understand the orbital interactions involved in these compounds so that they can approach their synthetic goals most effectively. …”
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717“…Photochemistry, the use of light to promote organic transformations, has been known for more than a century but only recently has revolutionized the way modern chemists are thinking. Except from transition metal-based complexes, small organic molecules have been introduced as catalysts or initiators. …”
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718“…Defining analytical chemistry as the measurement of isolated compositional features in a selected study object ignores the unique perspective that analytical chemists bring to twenty-first century science and society. …”
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719“…To achieve this goal, chemists traditionally choose the correct starting materials and reaction conditions, but it often lacks selectivity and efficiency. …”
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720“…[Image: see text] This contribution highlights a number of approaches developed by coordination and organometallic chemists that go beyond mainstream inorganic reactivity. …”
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