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961“…To address this issue, we present mofdscribe, a software ecosystem tailored to novice and seasoned digital chemists that streamlines the ideation, modeling, and publication process. …”
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962por Fernandes, Guilherme Felipe Santos, Scarim, Cauê Benito, Kim, Seong-Heun, Wu, Jingyue, Castagnolo, Daniele“…Therefore, this review article aims to compile the efforts of medicinal chemists who have explored this scaffold over the past decades and highlight the potential of the class for medicinal chemistry.…”
Publicado 2023
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963“…Inspired by multimetallic assemblies and their role in enzyme catalysis, chemists have developed a plethora of heterobimetallic complexes for application in homogeneous catalysis. …”
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964“…We hope that this Review may help chemists, biologists and immunologists to design the next generation of molecular imaging probes for T cells and anti-cancer immunotherapies.…”
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965“…An efficient and economical electrocatalyst as kinetic support is key to electrochemical reactions. For this reason, chemists have been working to investigate the basic changing of chemical principles when the system is confined in limited space with nanometer‐scale dimensions or sub‐microliter volumes. …”
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966“…Marine microbial natural products (MMNPs) have attracted increasing attention from microbiologists, taxonomists, ecologists, agronomists, chemists and evolutionary biologists during the last few decades. …”
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967“…We thus demonstrate that biosynthetic considerations and the joint effort of synthetic and natural product chemists can result in the identification of new members of a rare class of natural products.…”
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968“…[Image: see text] The ability to convert simple and common substrates into fluoroalkyl derivatives under mild conditions remains an important goal for medicinal and agricultural chemists. One representative example of a desirable transformation involves the conversion of aromatic and heteroaromatic ketones and aldehydes into aryl and heteroaryl β,β,β-trifluoroethylarenes and -heteroarenes. …”
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969“…Our mapping may also be of interest to chemists directly as it defines a dictionary from electronic structure to spin Hamiltonians with physical interactions.…”
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970por Qin, Tian, Skraba-Joiner, Sarah L., Khalil, Zeinab G., Johnson, Richard P., Capon, Robert J., Porco, John A.“…Chiral, dimeric natural products containing complex structures and interesting biological properties have inspired chemists and biologists for decades. A seven step total synthesis of the axially chiral, dimeric tetrahydroxanthone natural product rugulotrosin A is described. …”
Publicado 2015
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971“…In the last 20 years or so, chemists and molecular biologists have synthesized some novel DNA polyhedra. …”
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972por BÂRSU, CRISTIAN“…The historical value of this amphitheatre was completed in 1957 with bass relief carvings, representing important pharmacists and chemists, such as Carol Davila, Ştefan Minovici, Constantin I. …”
Publicado 2013
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973“…Our hope is that, by placing such compounds in the minds of the chemical community, they may gain more traction in drug discovery and inspire more synthetic chemists to develop methods for selective halogenation.…”
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974“…These recent breakthroughs greatly enhanced the efficiency of the tethering approach for olefin functionalization, and will make it even more attractive for synthetic chemists in the future.…”
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975por Thomas, Brian F“…The wide anatomical distribution and functional complexity of the cannabinoid system continue to indicate potential for both therapeutic and side effects, which offers challenges and opportunities for medicinal chemists involved in drug discovery and development.…”
Publicado 2017
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976por Mukhi, Priyabrata, Mohapatra, Swapna Sarita, Bhattacharjee, M., Ray, K.K., Muraleedharan, T.S., Arun, A., Sathyavathi, R., Juluri, R.R., Satyam, P.V., Panda, Alok K., Biswas, Ashis, Nayak, S., Bojja, Sreedhar, Pratihar, S., Roy, Sujit“…Mercury is one of the elements which had attracted the attention of the chemists and physicians of ancient India and China. …”
Publicado 2017
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977“…It is fascinating but challenging for nanoscientists to organize nanoparticles (NPs) into ordered architectures just as it is for chemists to manipulate atoms and molecules to form functional molecules and supramolecules. …”
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978Advanced Energy Storage Devices: Basic Principles, Analytical Methods, and Rational Materials Designpor Liu, Jilei, Wang, Jin, Xu, Chaohe, Jiang, Hao, Li, Chunzhong, Zhang, Lili, Lin, Jianyi, Shen, Ze Xiang“…Therefore, the underlying mechanisms and the electrochemical processes occurring upon charge storage may be confusing for researchers who are new to the field as well as some of the chemists and material scientists already in the field. …”
Publicado 2017
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979“…In this context, synthetic chemists have developed novel protein synthetic tools and state-of-the-art chemical ligation strategies for the preparation of homologous modified histones. …”
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980“…The current theory of catalyst activity in heterogeneous catalysis is mainly obtained from the study of catalysts with mono-phases, while most catalysts in real systems consist of multi-phases, the understanding of which is far short of chemists' expectation. Density functional theory (DFT) and micro-kinetics simulations are used to investigate the activities of six mono-phase and nine bi-phase catalysts, using CO hydrogenation that is arguably the most typical reaction in heterogeneous catalysis. …”
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