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1061“…However, incorporating fluorescent markers (FM) into BCPs can appear tricky; we thus intend to help chemists in this endeavor by reviewing recent advances made in the last 10 years. …”
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1065por Altshuler, Heinrich, Ostapova, Elena, Altshuler, Olga, Shkurenko, Galina, Malyshenko, Natalya, Lyrschikov, Sergey, Parshkov, RomanEnlace del recurso
Publicado 2018
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1067
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1068“…The diversity of microfluidic devices discourages biologists and chemists from applying this technique in their laboratories. …”
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1069por Dimiza, Filitsa, Barmpa, Amalia, Chronakis, Antonios, Hatzidimitriou, Antonios G., Sanakis, Yiannis, Papadopoulos, Athanasios N., Psomas, George“…One the main research goals of bioinorganic chemists is the synthesis of novel coordination compounds possessing biological potency. …”
Publicado 2023
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1070por Zhang, Shuo‐Qing, Xu, Li‐Cheng, Li, Shu‐Wen, Oliveira, João C. A., Li, Xin, Ackermann, Lutz, Hong, Xin“…By merging organic synthesis tactics and chemical informatics, we hope this Review can provide a guide map and intrigue chemists to revisit the digitalization and computerization of organic chemistry principles.…”
Publicado 2022
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1071por Brehmer, Tillman, Duong, Benny, Marquart, Manuela, Friedemann, Luise, Faust, Peter J., Boeker, Peter, Wüst, Matthias, Leppert, Jan“…This standardized procedure of measurements and calculations, presented in this work, have a useful benefit for all chromatographers, analytical chemists, and method developers because it can be used in their own laboratories to simplify the method development. …”
Publicado 2023
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1072“…The accumulated spectral and chromatographical data, as well as the established correlation between RI values and structures of regioisomeric hexanoates, provide (phyto)chemists with a tool that will make future identification of related natural compounds a straightforward task.…”
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1073por Hartung, Ingo V., Rudolph, Joachim, Mader, Mary M., Mulder, Monique P. C., Workman, Paul“…[Image: see text] Within druggable target space, new small-molecule modalities, particularly covalent inhibitors and targeted degraders, have expanded the repertoire of medicinal chemists. Molecules with such modes of action have a large potential not only as drugs but also as chemical probes. …”
Publicado 2023
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1074por Radwan, Mohamed O., Abd-Alla, Howaida I., Alsaggaf, Azhaar T., El-Mezayen, Hatem, Abourehab, Mohammed A. S., El-Beeh, Mohamed E., Tateishi, Hiroshi, Otsuka, Masami, Fujita, Mikako“…In the last decade, gypsogenin has attracted widespread attention from medicinal chemists by virtue of its prominent anti-cancer potential. …”
Publicado 2023
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1075“…The high reactivity and tendency to undergo various rearrangements have piqued the interest of synthetic chemists in heterocycles with N-oxide fragments. Quinoxaline 1,4-dioxides are an example of an important class of heterocyclic N-oxides, whose wide range of biological activity determines the prospects of their practical use in the development of drugs of various pharmaceutical groups. …”
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1076por Zhan, Faqiang, Shunthirasingham, Chubashini, Li, Yuening, Oh, Jenny, Lei, Ying Duan, Ben Chaaben, Amina, Dalpé Castilloux, Abigaëlle, Lu, Zhe, Lee, Kelsey, Gobas, Frank A. P. C., Alexandrou, Nick, Hung, Hayley, Wania, Frank“…Long ignored by environmental chemists because of their predominantly natural origin—namely, synthesis by terrestrial wood-rotting fungi, marine algae, and invertebrates—knowledge of their environmental pathways remains limited. …”
Publicado 2023
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1077“…These synthetic studies, as well as syntheses of the discorhabdins by various chemists to-date, are reviewed here.…”
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1078“…The activating effect of an allylic hydroxy group in metathesis has been known for more than 10 years, and many organic chemists have taken advantage of this positive influence for efficient synthesis of natural products. …”
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1079“…Through controlled synthesis and molecular assembly, biological systems are able to organize molecules into supramolecular structures that carry out sophisticated processes. Although chemists have reported a few examples of supramolecular assembly in water, the controlled covalent synthesis of large molecules and structures in vivo has remained challenging. …”
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1080por Strobelt, Hendrik, Bertini, Enrico, Braun, Joachim, Deussen, Oliver, Groth, Ulrich, Mayer, Thomas U, Merhof, Dorit“…We describe the requirements we collected during our collaboration with biologists and chemists, the design rationale behind the tool, and two case studies on different datasets. …”
Publicado 2012
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