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1701por Lambert, Christopher, Schweizer, Lena, Matio Kemkuignou, Blondelle, Anoumedem, Elodie Gisèle M., Kouam, Simeon F., Marin-Felix, Yasmina“…Their relevance for biotechnology and agriculture attracts the attention of taxonomists and natural product chemists alike in context of plant protection and exploitation for their potential to produce bioactive secondary metabolites. …”
Publicado 2023
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1702por Rowbotham, Jack S., Nicholson, Jake H., Ramirez, Miguel A., Urata, Kouji, Todd, Peter M. T., Karunanithy, Gogulan, Lauterbach, Lars, Reeve, Holly A., Baldwin, Andrew J., Vincent, Kylie A.“…To demonstrate the benefits of the approach for enabling the workflow of protein NMR chemists, we prepared l-[α-(2)H,(15)N, β-(13)C]-alanine and integrated it into a large (>400 kDa) heat-shock protein oligomer, which was subsequently analysable by methyl-TROSY techniques, revealing new structural information.…”
Publicado 2023
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1703“…Laboratory analysis was done using the methods described by the Association of Official Analytical Chemists AOAC (1995 and 2000). The amount of protein was 7.13 ± 0.04% and 21.73 ± 0.02% in V. doniana fruits while the fat contents were 2.4 ± 0.00% and 1.9 ± 0.10% in V. doniana fruits. …”
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1704“…Modelling procedures generally require significant training and computing resources, which is often impractical for most experimental chemists and biologists. Shape has been developed to improve the availability of modelling in this field. …”
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1705“…We checked the microbial load and nutrient values (using International Standard IS and Association of Official Analytical chemists AOAC methods) RESULTS: The powdered form of Saubhagya Shunthi Churna yielded a weight loss of approximately 17.64% of the total weight of ingredients. …”
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1706“…The highly formulaic style of writing most chemists adopt make their contributions well suited to high-throughput Natural Language Processing (NLP) approaches. …”
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1707“…There have been many efforts made to create sets of 'rules' or 'filters' which, it is hoped, will help chemists to identify 'drug-like' molecules from 'non-drug' molecules. …”
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1708por Kapoor, Sunil K., Raman, A. Venkat, Sachdeva, Kuldeep Singh, Satyanarayana, Srinath“…The study showed that informal providers and retail chemists were the first point of contact and source of clinical advice for two-third of the patients, while the rest sought medical care from qualified providers directly. …”
Publicado 2012
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1709por Martin, Elyette, Monge, Aurélien, Duret, Jacques-Antoine, Gualandi, Federico, Peitsch, Manuel C, Pospisil, Pavel“…In the UCD, each molecule is registered only once (uniqueness), structures with alternative representations are entered in a uniform way (normalization), and the chemical structure drawings are recognizable to chemists and to a cartridge. In brief, structural molecules are entered as neutral entities which can be associated with a salt. …”
Publicado 2012
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1710por Moldovan, Carmen, Iosub, Rodica, Codreanu, Cecilia, Firtat, Bogdan, Necula, Daniel, Brasoveanu, Costin, Stan, Ion“…The target of the research is to develop a new and reconfigurable platform according to the particular applications needs, as a tool for the biologist, chemists and medical doctors working is the field of cell culture monitoring in terms of growth, maintenance conditions, reaction to electrical or chemical stimulation (drugs, toxicants, etc.). …”
Publicado 2012
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1711por Qandil, Amjad M.“…The design and the synthesis of prodrugs for nonsteroidal anti-inflammatory drugs (NSAIDs) have been given much attention by medicinal chemists, especially in the last decade. As a therapeutic group, NSAIDs are among the most widely used prescribed and over the counter (OTC) medications. …”
Publicado 2012
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1712“…A number of historical texts are investigated to ascertain the optimum conditions for the preparation of synthetic ultramarine, using preparative methods that would have been available to alchemists and colour chemists of the nineteenth century. The effect of varying the proportion of sulphur in the starting material on the colour of the final product is investigated. …”
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1713por Silverio, Daniel L., Torker, Sebastian, Pilyugina, Tatiana, Vieira, Erika M., Snapper, Marc L., Haeffner, Fredrik, Hoveyda, Amir H.“…The discovery of new catalysts that can generate complex organic compounds via enantioselective transformations is central to advances in the life sciences;(i) for this reason, many chemists try to discover catalysts that can be used to produce chiral molecules with a strong preference for one mirror image isomer.…”
Publicado 2013
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1714“…In Australia and increasingly worldwide, methamphetamine is one of the most commonly seized drugs analysed by forensic chemists. The current well-established GC/MS methods used to identify and quantify methamphetamine are lengthy, expensive processes, but often rapid analysis is requested by undercover police leading to an interest in developing this new analytical technique. …”
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1715por Azam, Faizul, Abugrain, Ismaiel Mohamed, Sanalla, Mohamed Hussin, Elnaas, Radwan Fatahalla, Rajab, Ibrahim Abdassalam Ibn“…In this regard, computational tools have helped medicinal chemists modify and optimize molecules to potent drug candidates with better pharmacokinetic profiles, and guiding biologists and pharmacologists to explore new disease genes as well as novel drug targets. …”
Publicado 2013
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1716por Hilbig, Matthias, Urbaczek, Sascha, Groth, Inken, Heuser, Stefan, Rarey, Matthias“…Working with small‐molecule datasets is a routine task for cheminformaticians and chemists. The analysis and comparison of vendor catalogues and the compilation of promising candidates as starting points for screening campaigns are but a few very common applications. …”
Publicado 2013
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1717“…EU-OPENSCREEN integrates high-capacity screening platforms throughout Europe, which share a rationally selected compound collection comprising up to 300,000 (commercial and proprietary compounds collected from European chemists). By testing systematically this chemical collection in hundreds of assays originating from very different biological themes, the screening process generates enormous amounts of information about the biological activities of the substances and thereby steadily enriches our understanding of how and where they act.…”
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1718por Mussarat, Sakina, Amber, Rahila, Tariq, Akash, Adnan, Muhammad, AbdElsalam, Naser M., Ullah, Riaz, Bibi, Roqaia“…We invite the attention of pharmacologists and chemists for further exploration of plants having high Fic, FL, and PR values in the present study. …”
Publicado 2014
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1719“…These therapeutically important secondary metabolites are assembled and modified by dedicated biosynthetic pathways in their host living organisms. Traditionally, chemists have attempted to synthesize natural product analogs that are important sources of new drugs. …”
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1720por Duan, Xiaoyue, Yang, Feifei, Antono, Erin, Yang, Wenge, Pianetta, Piero, Ermon, Stefano, Mehta, Apurva, Liu, Yijin“…Our approach can rapidly provide a concise representation of a large and complex dataset to materials scientists and chemists. For example, it shows that the surface of common Nd(2)Fe(14)B magnet is chemically and structurally very different from the bulk, suggesting a possible surface alteration effect possibly due to the corrosion, which could affect the material’s overall properties.…”
Publicado 2016
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