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  1. 1721
    “…The accuracy, precision, and stability met with the acceptance criteria of the AOAC (Association of Official Analytical Chemists) International. According to these results, the described HPLC-MS/MS method is adequately sensitive, repeatable and suitable for the large-scale analysis of compounds in biological fluids.…”
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    Development of an Advanced HPLC–MS/MS Method for the Determination of Carotenoids and Fat-Soluble Vitamins in Human Plasma
  2. 1722
    “…Hydroacylation reactions and aza-benzoin reactions have attracted considerable attention from experimental chemists. Recently, Wang et al. reported an interesting reaction of N-heterocyclic carbene (NHC)-catalyzed addition of aldehyde to enamide, in which both hydroacylation and aza-benzoin reactions may be involved. …”
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    Insights into the Competing Mechanisms and Origin of Enantioselectivity for N-Heterocyclic Carbene-Catalyzed Reaction of Aldehyde with Enamide
  3. 1723
    por Fürstner, Alois
    Publicado 2016
    “…The challenges are significant, not least at the analytical frontier; their mastery mandates a mindset that differs from the routines that most organic chemists interested in (noble metal) catalysis tend to cultivate. …”
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    Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion
  4. 1724
    “…Unveiling the determinants for transferase and hydrolase activity in glycoside hydrolases would allow using their vast diversity for creating novel transglycosylases, thereby unlocking an extensive toolbox for carbohydrate chemists. Three different amino acid substitutions at position 220 of a GH1 β-glucosidase from Thermotoga neapolitana caused an increase of the ratio of transglycosylation to hydrolysis (r (s)/r (h)) from 0.33 to 1.45–2.71. …”
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    Eliminating hydrolytic activity without affecting the transglycosylation of a GH1 β-glucosidase
  5. 1725
    por Gürsoy, Oya, Smieško, Martin
    Publicado 2017
    “…In order to enable computational chemists and modelers to efficiently use available software tools, we have additionally performed several focused analyses on ligands, grouped according to descriptors most relevant for the rational drug design. …”
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    Searching for bioactive conformations of drug-like ligands with current force fields: how good are we?
  6. 1726
    por Lichtman, Marshall A.
    Publicado 2017
    “…Alfred Nobel was one of the most successful chemists, inventors, entrepreneurs, and businessmen of the late nineteenth century. …”
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    Alfred Nobel and His Prizes: From Dynamite to DNA
  7. 1727
    “…Since its discovery in the 1920s, physicists and chemists have used Raman scattering to investigate the chemical composition of a vast range of both liquid and solid materials. …”
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    Raman spectroscopy and regenerative medicine: a review
  8. 1728
    “…The PAMBD and its future iterations will provide a valuable resource to biologists, natural product chemists and clinicians in identifying active compounds, potential biomarkers and clinical diagnostics.…”
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    PAMDB: a comprehensive Pseudomonas aeruginosa metabolome database
  9. 1729
    “…However, the high cost of noble metals and poor recycling performance provides an opportunity for chemists to look for alternate options. Herein, we present the use of Lanthanum hydroxide as support for loading ultra-low amount of Pd for hydrogenation and cross-coupling reactions. …”
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    Interfacial Phenomenon and Nanostructural Enhancements in Palladium Loaded Lanthanum Hydroxide Nanorods for Heterogeneous Catalytic Applications
  10. 1730
    “…This work provides an important step toward developing both a fundamental conceptual picture and a practical experimental handle with which synthetic chemists, spectroscopists, and theoreticians may collaborate to engineer cheap and efficient photocatalytic materials capable of performing coulombically demanding chemical transformations.…”
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    Excited state electron and energy relays in supramolecular dinuclear complexes revealed by ultrafast optical and X-ray transient absorption spectroscopy
  11. 1731
    por Feng, Fan, Lai, Luhua, Pei, Jianfeng
    Publicado 2018
    “…Up to now, however, these methods still cannot replace experienced human organic chemists due to their relatively low accuracies. Future new algorithms with the aid of powerful computational hardware will make this topic promising and with good prospects.…”
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    Computational Chemical Synthesis Analysis and Pathway Design
  12. 1732
    “…ProTox-II provides a freely available webserver for in silico toxicity prediction for toxicologists, regulatory agencies, computational and medicinal chemists, and all users without login at http://tox.charite.de/protox_II. …”
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    ProTox-II: a webserver for the prediction of toxicity of chemicals
  13. 1733
    por Rowe, Walter
    Publicado 2001
    “…Gross’s manual for examining magistrates suggests ways in which the expertise of chemists, biologists, geologists, and other natural scientists could contribute to investigations. …”
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    Founding Editorial – Forensics and TheScientificWorld
  14. 1734
    “…The test flours were analyzed using the Association of the Official Analytical Chemists (AOAC) methods to determine their nutrient composition before preparation of the porridges. …”
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    Influence of maturity, smoking, and drying of fresh maize on sensory acceptability and nutritional content of the developed porridges
  15. 1735
    “…We hope this review not only provides a comprehensive summary of aptamer selection and aptasensor development for marine biotoxins, but also arouses a broad readership amongst academic researchers and industrial chemists.…”
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    Aptamers and Aptasensors for Highly Specific Recognition and Sensitive Detection of Marine Biotoxins: Recent Advances and Perspectives
  16. 1736
    “…Modified Association of Official Analytical Chemists (AOAC) proximate and mineral analyses were carried out on the insect’s third instar larvae, pupal, and adult stages to determine the nutritional composition. …”
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    The Diet for Edible-Nest Swiftlets: Nutritional Composition and Cost of Life Stages of Megaselia scalaris Loew (Diptera: Phoridae) Bred on 3 Commercial Breeding Materials
  17. 1737
    “…Moreover, exogenous AR agonists, antagonists, or allosteric modulators can be applied for therapeutic benefit, and medicinal chemists working toward that goal have reported thousands of such agents. …”
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    Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
  18. 1738
    “…The DFT is the most accurate way in which chemists may address the behavior of the molecular world through large models mimicking chemical complexity. …”
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    Role of Mineral Surfaces in Prebiotic Chemical Evolution. In Silico Quantum Mechanical Studies
  19. 1739
    “…Development of new calcium chelators with two-photon absorption (TPA) properties is a state-of-the-art challenge for chemists. In this study, we report the first and efficient synthesis of 5-bromo-2-nitrobenzyl-substituted ethylene glycol tetraacetic acid (EGTA) as a platform for a new generation of calcium chelators with TPA properties in the near-infrared region. …”
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    Design and Synthesis of a 4-Nitrobromobenzene Derivative Bearing an Ethylene Glycol Tetraacetic Acid Unit for a New Generation of Caged Calcium Compounds with Two-Photon Absorption Properties in the Near-IR Region and Their Application in Vivo
  20. 1740
    “…However, due to its extensive bioactivities, some scientists hold a skeptical point of view toward curcumin and described curcumin as a “deceiver” to chemists. The objective of this study was to explore curcumin's another possibility as a potential supplementary leading compound to cancer treatments. …”
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    Curcumin: From a controversial “panacea” to effective antineoplastic products
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